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Metformin (Glucophage)

A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)
Also Known As:
Glucophage; Dimethylbiguanidine; Dimethylguanylguanidine; Imidodicarbonimidic diamide, N,N-dimethyl-
Networked: 5682 relevant articles (774 outcomes, 1406 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Diabetes Prevention Program Research Group: 32 articles (04/2015 - 02/2002)
2. Ibáñez, Lourdes: 29 articles (11/2015 - 06/2002)
3. Palomba, Stefano: 29 articles (05/2014 - 10/2004)
4. Falbo, Angela: 26 articles (05/2014 - 10/2004)
5. Orio, Francesco: 26 articles (05/2014 - 10/2004)
6. Scheen, A J: 25 articles (09/2015 - 03/2000)
7. Menendez, Javier A: 24 articles (05/2015 - 02/2008)
8. Zullo, Fulvio: 24 articles (02/2012 - 10/2004)
9. Derosa, Giuseppe: 22 articles (11/2015 - 05/2005)
10. Nestler, John E: 22 articles (06/2012 - 02/2002)

Related Diseases

1. Insulin Resistance
2. Type 2 Diabetes Mellitus (MODY)
3. Neoplasms (Cancer)
4. Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
5. Weight Loss (Weight Reduction)

Related Drugs and Biologics

1. Insulin (Novolin)
2. Glucose (Dextrose)
3. pioglitazone (Actos)
4. Clomiphene (Clomifene)
5. rosiglitazone (Avandia)
6. Thiazolidinediones
7. Glyburide (Glibenclamide)
8. Acarbose
9. vildagliptin
10. sitagliptin (Januvia)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Oral Administration
4. Chemoprevention
5. Aftercare (After-Treatment)