|1.||Reiser, Georg: 3 articles (03/2013 - 10/2011)|
|2.||Stricker, Rolf: 3 articles (03/2013 - 10/2011)|
|3.||Love, Seth: 2 articles (01/2012 - 01/2008)|
|4.||Borrmann, Claudia: 2 articles (11/2011 - 10/2011)|
|5.||Li, Hongzhe: 2 articles (01/2008 - 04/2007)|
|6.||Sharma, Avadhesh C: 2 articles (10/2004 - 10/2003)|
|7.||Gupta, Akanksha: 2 articles (10/2004 - 10/2003)|
|8.||Kelwick, Richard: 1 article (01/2015)|
|9.||Wheeler, Grant N: 1 article (01/2015)|
|10.||Edwards, Dylan R: 1 article (01/2015)|
|1.||Hypertension (High Blood Pressure)
10/01/2001 - "1. The aim of the present study was to determine the effects of the metalloendopeptidase (EP) 24.15 and 24.16 inhibitor N-[1-(R,S)-carboxy-3-phenylpropyl]-Ala-Aib-Tyr-p-aminobenzoate (JA-2) on haemodynamics and renal function in conscious rabbits with two-kidney, two-wrapped hypertension. "
10/01/2001 - "Metalloendopeptidases EC 126.96.36.199 and EC 188.8.131.52 and bradykinin B2 receptors do not play important roles in renal wrap hypertension in rabbits."
01/01/1995 - "Pharmacokinetic-pharmacodynamic (PK-PD) modeling for a new antihypertensive agent (neutral metalloendopeptidase inhibitor SCH 42354) in patients with mild to moderate hypertension."
07/01/2003 - "Metalloendopeptidases of the M13 family were shown to play critical roles in normal physiological processes such as pain control, hypertension and phosphate metabolism, and in pathological states such as Alzheimer's disease. "
04/01/2000 - "We have found statistically significant increases (P < 0.001) in the activity of both lysosomal and ET-1 peptidase in the urine in patients with hypertension and in children with chronic renal failure compared with healthy subjects or children with stable renal allograft Human kidney contains an acidic, highly specific endothelin-1 inactivating metalloendopeptidase that may have a key role in the regulation of concentrations of renal and circulating endothelins. "
10/01/2004 - "Despite minimal hemodynamic alterations endotoxemia modulates NOS and p38-MAPK phosphorylation via metalloendopeptidases."
10/01/2003 - "We concluded that inhibition of metalloendopeptidases during early endotoxemia not only decreased the biosynthesis of ET-1 in heart locally but also simultaneously down-regulated myocardial protein expression of iNOS and p38-MAPK phosphorylation in the later stage of endotoxemia."
10/01/2003 - "These results indicated that inhibition of metalloendopeptidase during induction of endotoxemia could regulate the phosphorylation of myocardial p38-MAPK and iNOS protein expression at 24-h post endotoxemia. "
10/01/2004 - "In the present study, we hypothesized that endotoxemia produces metalloendopeptidase (MEPD)-dependent generation of endothelin-1 (ET-1) and alters NOS expression correlating with p38-mitogen-activated protein kinase (MAPK) phosphorylation in thoracic aorta. "
10/01/2003 - "Metalloendopeptidase inhibition regulates phosphorylation of p38-mitogen-activated protein kinase and nitric oxide synthase in heart after endotoxemia."
|4.||Periodontal Diseases (Periodontal Disease)
10/01/2013 - "The present study suggests that the severity of periodontal disease may be associated with the expression of metalloendopeptidase genes, including NEP, ECE1 and ADAM17, in the buccal mucosal epithelium."
10/01/2013 - "This study focused on three metalloendopeptidases - NEP, ECE-1 and ADAM17 - in the oral buccal mucosal epithelium of patients with periodontal diseases and investigated the relationship between their gene-expression levels and periodontal disease. "
10/01/2013 - "Periodontal disease and gene-expression levels of metalloendopeptidases in human buccal mucosal epithelium."
|5.||Migraine Disorders (Migraine)
|2.||Endothelin-1 (Endothelin 1)
|3.||Protein Kinases (Protein Kinase)
|4.||Pancreatic Elastase (Elastase)
|6.||Neprilysin (Neutral Endopeptidase)
|9.||Amyloid (Amyloid Fibrils)
|1.||Homologous Transplantation (Allograft)