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Meningomyelocele (Myelomeningocele)

Congenital, or rarely acquired, herniation of meningeal and spinal cord tissue through a bony defect in the vertebral column. The majority of these defects occur in the lumbosacral region. Clinical features include PARAPLEGIA, loss of sensation in the lower body, and incontinence. This condition may be associated with the ARNOLD-CHIARI MALFORMATION and HYDROCEPHALUS. (From Joynt, Clinical Neurology, 1992, Ch55, pp35-6)
Also Known As:
Myelomeningocele; Acquired Meningomyelocele; Myelomeningocele, Acquired; Acquired Meningomyeloceles; Acquired Myelomeningocele; Acquired Myelomeningoceles; Meningomyelocele, Acquired; Meningomyeloceles; Meningomyeloceles, Acquired; Myeloceles; Myelomeningoceles; Myelomeningoceles, Acquired; Myelocele
Networked: 776 relevant articles (33 outcomes, 71 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hydrocephalus (Hydrocephaly)
2. Neurogenic Urinary Bladder (Bladder, Neurogenic)
3. Abnormal Reflex (Hyperreflexia)
4. Meningitis
5. Infection

Experts

1. Adzick, N Scott: 10 articles (12/2015 - 11/2002)
2. Au, Kit Sing: 9 articles (06/2015 - 08/2010)
3. Northrup, Hope: 9 articles (06/2015 - 08/2010)
4. Flake, Alan W: 9 articles (12/2013 - 09/2003)
5. Nejat, Farideh: 8 articles (08/2013 - 06/2006)
6. Johnson, Mark P: 6 articles (12/2015 - 11/2002)
7. Wilson, R Douglas: 6 articles (01/2009 - 04/2002)
8. Rendeli, C: 4 articles (01/2014 - 01/2006)
9. Ausili, E: 4 articles (01/2014 - 01/2006)
10. Fletcher, Jack M: 4 articles (10/2012 - 08/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Meningomyelocele:
1. Type A Botulinum Toxins (Botulinum A Toxin)FDA Link
2. Botulinum Toxins (Botulinum Toxin)IBA
3. cytidylyl-(3'-5')-cytidine (CpC)IBA
4. glutaraldehyde-cross-linked collagenIBA
5. Congenital diaphragmatic herniaIBA
6. OxygenIBA
7. onabotulinumtoxinA (Botox)FDA Link
8. Folic Acid (Vitamin M)FDA LinkGeneric
9. CollagenIBA
10. CosmeticsIBA

Therapies and Procedures

1. Ventriculoperitoneal Shunt
2. Injections
3. Transplants (Transplant)
4. Orthotic Devices (Orthosis)
5. Intermittent Urethral Catheterization