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Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis)

An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111)
Also Known As:
Streptococcus pneumoniae Meningitis; Meningitis, Pneumococcal; Experimental Pneumococcal Meningitis; Meningitis, Pneumococcal, Experimental; Meningitis, Pneumococcal, Penicillin-Resistant; Meningitis, Pneumococcal, Recurrent; Experimental Pneumococcal Meningitides; Meningitides, Streptococcus pneumoniae; Meningitis, Experimental Pneumococcal; Pneumococcal Meningitides; Pneumococcal Meningitides, Experimental; Pneumococcal Meningitis, Experimental; Streptococcus pneumoniae Meningitides; Meningitis, Streptococcus pneumoniae
Networked: 690 relevant articles (65 outcomes, 87 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Meningitis
2. Infection
3. Hearing Loss (Hearing Impairment)
4. Inflammation
5. Pneumonia (Pneumonitis)

Experts

1. Leib, Stephen L: 26 articles (01/2015 - 09/2002)
2. Koedel, Uwe: 20 articles (04/2014 - 01/2002)
3. Barichello, Tatiana: 19 articles (08/2015 - 12/2009)
4. van de Beek, Diederik: 17 articles (01/2015 - 11/2002)
5. Generoso, Jaqueline S: 16 articles (08/2015 - 06/2010)
6. Pfister, Hans-Walter: 16 articles (04/2014 - 01/2002)
7. Quevedo, João: 15 articles (08/2015 - 12/2009)
8. Grandgirard, Denis: 12 articles (01/2015 - 05/2003)
9. Comim, Clarissa M: 12 articles (01/2015 - 12/2009)
10. Nau, Roland: 12 articles (01/2013 - 12/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pneumococcal Meningitis:
1. Ceftriaxone (Ceftriaxon)FDA LinkGeneric
2. Dexamethasone (Maxidex)FDA LinkGeneric
3. VancomycinFDA LinkGeneric
4. Penicillins (Penicillin)FDA Link
5. Rifampin (Rifampicin)FDA LinkGeneric
6. DaptomycinFDA Link
7. Ciprofloxacin (Cipro)FDA LinkGeneric
8. meropenem (Merrem)FDA LinkGeneric
9. TeicoplaninIBA
10. clinafloxacinIBA

Therapies and Procedures

1. Cochlear Implantation
2. Splenectomy
3. Catheters
4. Intramuscular Injections
5. Cochlear Implants (Cochlear Implant)