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Medulloblastoma

A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
Also Known As:
Medulloblastoma, Adult; Medulloblastoma, Childhood; Melanocytic Medulloblastoma; Adult Medulloblastoma; Adult Medulloblastomas; Childhood Medulloblastoma; Childhood Medulloblastomas; Desmoplastic Medulloblastoma; Desmoplastic Medulloblastomas; Medulloblastoma, Melanocytic; Medulloblastomas; Medulloblastomas, Adult; Medulloblastomas, Childhood; Medulloblastomas, Desmoplastic; Medulloblastomas, Melanocytic; Medullomyoblastomas; Melanocytic Medulloblastomas; Arachnoidal Cerebellar Sarcoma, Circumscribed; Medulloblastoma, Desmoplastic; Medullomyoblastoma; Sarcoma, Cerebellar, Circumscribed Arachnoidal
Networked: 2504 relevant articles (132 outcomes, 380 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Primitive Neuroectodermal Tumors (PNET)
3. Brain Neoplasms (Brain Tumor)
4. Astrocytoma (Pilocytic Astrocytoma)
5. Neoplasm Metastasis (Metastasis)

Experts

1. Taylor, Michael D: 63 articles (11/2015 - 09/2003)
2. Northcott, Paul A: 38 articles (06/2015 - 04/2009)
3. Kool, Marcel: 37 articles (05/2015 - 02/2006)
4. Gajjar, Amar: 37 articles (03/2015 - 08/2002)
5. Rutkowski, Stefan: 36 articles (11/2015 - 03/2005)
6. Eberhart, Charles G: 34 articles (03/2014 - 08/2002)
7. Korshunov, Andrey: 32 articles (02/2015 - 05/2004)
8. Remke, Marc: 30 articles (11/2015 - 04/2009)
9. Pfister, Stefan M: 30 articles (06/2015 - 10/2010)
10. Clifford, Steven C: 27 articles (11/2015 - 10/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Medulloblastoma:
1. Vincristine (Oncovin)FDA LinkGeneric
2. Cisplatin (Platino)FDA LinkGeneric
3. Etoposide (VP 16)FDA LinkGeneric
4. Cyclophosphamide (Cytoxan)FDA LinkGeneric
5. Methotrexate (Mexate)FDA LinkGeneric
6. Lomustine (CCNU)FDA Link
7. Procarbazine (Matulane)FDA Link
8. Carboplatin (JM8)FDA LinkGeneric
9. DNA (Deoxyribonucleic Acid)IBA
10. resveratrolIBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Radiotherapy
3. Heterologous Transplantation (Xenotransplantation)
4. Adjuvant Chemotherapy
5. Combination Drug Therapy (Combination Chemotherapy)