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Maprotiline (Ludiomil)

A bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, including side effects associated with its use.
Also Known As:
Ludiomil; Deprilept; Maprotilin; Psymion; Ba-34,276; Declimed Brand of Maprotiline Hydrochloride; Dibencycladine; Dolorgiet Brand of Maprotiline Hydrochloride; Hexal Brand of Maprotiline Mesylate; Holsten Brand of Maprotiline Hydrochloride; Lundbeck Brand of Maprotiline Hydrochloride; Maprolu; Maprotilin Holsten; Maprotilin-TEVA; Maprotilin-neuraxpharm; Maprotilin-ratiopharm; Maprotiline Hydrochloride; Maprotiline Mesylate; Mirpan; N-Methyl-9,10-ethanoanthracene-9(10H)-propylamine; Novartis Brand of Maprotiline Hydrochloride; Novo-Maprotiline; Novopharm Brand of Maprotiline Hydrochloride; Teva Brand of Maprotiline Hydrochloride; ct-Arzneimittel Brand of Maprotiline Hydrochloride; maprotilin von ct; neuraxpharm Brand of Maprotiline Hydrochloride; ratiopharm Brand of Maprotiline Hydrochloride; Ba34,276; Hydrochloride, Maprotiline; Maprotilin TEVA; Maprotilin neuraxpharm; Maprotilin ratiopharm; Mesylate, Maprotiline; Novo Maprotiline; 9,10-Ethanoanthracene-9(10H)-propanamine, N-methyl-
Networked: 251 relevant articles (16 outcomes, 26 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Hajhashemi, Valiollah: 2 articles (08/2015 - 01/2011)
2. Minaiyan, Mohsen: 2 articles (08/2015 - 03/2013)
3. Cloonan, Suzanne M: 2 articles (04/2011 - 03/2010)
4. Skoromets, A A: 2 articles (01/2007 - 01/2000)
5. Amelin, A V: 2 articles (01/2007 - 01/2000)
6. Jiann, Bang-Ping: 2 articles (07/2004 - 07/2004)
7. Jan, Chung-Ren: 2 articles (07/2004 - 07/2004)
8. Yeh, Jeng-Hsien: 2 articles (07/2004 - 07/2004)
9. Huang, Jong-Khing: 2 articles (07/2004 - 07/2004)
10. Chen, Wei-Chuan: 2 articles (07/2004 - 07/2004)

Related Diseases

1. Depressive Disorder (Melancholia)
2. Pain (Aches)
3. Neuralgia (Stump Neuralgia)
4. Major Depressive Disorder (Major Depressive Disorders)
5. Dysthymic Disorder
01/01/1991 - "In a six-week double-blind randomized trial, preceded by a one-week period of single-blind placebo treatment, the efficacy and the side-effects of fluvoxamine (100-300 mg/d) (n = 24) and maprotiline (50-150 mg/d) (n = 24) were compared in moderately depressed outpatients with DSM-III Major Depression (n = 22) or Dysthymic Disorder (n = 26). "
01/01/1984 - "Maprotiline hydrochloride tablets were given to 266 patients with either a dysthymic disorder or a major depressive disorder. "
01/01/1985 - "The authors present a pilot study utilizing the anti-depressant, maprotiline hydrochloride (Ludiomil) to determine its effects on the mental depression and immune reactions of T&B lymphocytes in patients with neurotic depression (dysthymic disorder by DSM III). "
03/01/1995 - "In patients with major depression without melancholia or psychotic features, depressed bipolar disorder or dysthymic disorder, the antidepressant efficacy of short term (4 weeks to 3 months) tianeptine therapy appears to be similar to that of amitriptyline, imipramine and fluoxetine and may be superior to that of maprotiline in patients with coexisting depression and anxiety. "
04/01/2011 - "We defined antidepressants as those with a letter of approval by the US, Canadian, or European Union drug regulatory agencies for treatment of MDD or dysthymic disorder, which included the following: amitriptyline, nortriptyline, imipramine, desipramine, clomipramine, trimipramine, protriptyline, dothiepin, doxepin, lofepramine, amoxapine, maprotiline, amineptine, nomifensine, bupropion, phenelzine, tranylcypromine, isocarboxazid, moclobemide, brofaromine, fluoxetine, sertraline, paroxetine, citalopram, escitalopram, fluvoxamine, zimelidine, tianeptine, ritanserin, trazodone, nefazodone, agomelatine, venlafaxine, desvenlafaxine, duloxetine, milnacipran, reboxetine, mirtazapine, and mianserin. "

Related Drugs and Biologics

1. Antidepressive Agents (Antidepressants)
2. Amitriptyline (Elavil)
3. Norepinephrine (Noradrenaline)
4. Serotonin (5 Hydroxytryptamine)
5. Fluoxetine (Prozac)
6. Paroxetine (Paxil)
7. Bupropion (Wellbutrin)
8. mirtazapine (Rexer)
9. Clomipramine (Anafranil)
10. Trazodone (Trittico)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Hemoperfusion
3. Intensive Care (Surgical Intensive Care)
4. Traction
5. Intravenous Infusions