Avian Malaria

Any of a group of infections of fowl caused by protozoa of the genera PLASMODIUM, Leucocytozoon, and Haemoproteus. The life cycles of these parasites and the disease produced bears strong resemblance to those observed in human malaria.

Also Known As:

Networked: 132 relevant articles (7 outcomes, 13 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Malaria
2.	Infections
3.	Parasitemia
4.	Coinfection
5.	Psychomotor Agitation (Akathisia)

Experts

1.	Valkiūnas, Gediminas: 11 articles (05/2022 - 05/2007)
2.	Palinauskas, Vaidas: 9 articles (01/2022 - 12/2011)
3.	Bensch, Staffan: 8 articles (06/2014 - 07/2004)
4.	Hellgren, Olof: 7 articles (06/2021 - 07/2004)
5.	Gandon, Sylvain: 3 articles (01/2018 - 12/2010)
6.	Nicot, Antoine: 3 articles (01/2018 - 12/2010)
7.	Patra, Kailash P: 3 articles (01/2018 - 09/2005)
8.	Rivero, Ana: 3 articles (01/2018 - 12/2010)
9.	Vinetz, Joseph M: 3 articles (01/2018 - 09/2005)
10.	Pattaradilokrat, Sittiporn: 3 articles (01/2017 - 11/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Avian Malaria:

1.	ArtesunateIBA 11/08/2013 - "In vivo transmission blocking activities of artesunate on the avian malaria parasite Plasmodium gallinaceum." 01/15/2017 - "Artesunate-tafenoquine combination therapy promotes clearance and abrogates transmission of the avian malaria parasite Plasmodium gallinaceum." 01/15/2017 - "The objectives of this study were to evaluate the efficacy of a relatively new antimalarial compound, tafenoquine (TQ), and a combination of TQ and a low dose of artesunate (ATN) on the in vivo blood stage multiplication, gametocyte development and transmission of the avian malaria parasite Plasmodium gallinaceum to the vector Aedes aegypti. " 06/01/2014 - "The efficacy of artesunate, chloroquine, doxycycline, primaquine and a combination of artesunate and primaquine against avian malaria in broilers."
2.	DNA (Deoxyribonucleic Acid)IBA 05/01/2011 - "Entomological study on transmission of avian malaria parasites in a zoological garden in Japan: bloodmeal identification and detection of avian malaria parasite DNA from blood-fed mosquitoes." 07/05/2017 - "Following DNA extraction, all samples were screened for the presence of DNA of filarioid helminths and avian malaria agents by PCR techniques. " 12/01/2016 - "Acquiring genomic material from avian malaria parasites for genome sequencing has proven problematic due to the nucleation of avian erythrocytes, which produces a large ratio of host to parasite DNA (∼1 million to 1 bp). " 10/01/2013 - "Penguins were also tested for the prevalence of avian malaria parasite DNA using a polymerase chain reaction (PCR) screening. " 09/01/2009 - "To indicate the competent vectors of avian malaria parasite, we collected mosquitoes at a zoological garden in Japan and examined for the avian malaria parasite DNA. "
3.	Antimalarials (Antimalarial Agents)IBA 02/01/1955 - "Chemotherapy of avian malarias: III. Trial of certain standard antimalarials on Plasmodium hexamerium and P. " 01/15/2017 - "The objectives of this study were to evaluate the efficacy of a relatively new antimalarial compound, tafenoquine (TQ), and a combination of TQ and a low dose of artesunate (ATN) on the in vivo blood stage multiplication, gametocyte development and transmission of the avian malaria parasite Plasmodium gallinaceum to the vector Aedes aegypti. " 11/01/1966 - "Effect of the antimalarial chloroquine on the phospholipid metabolism of avian malaria and heart tissue."
4.	DNA VaccinesIBA 06/01/2004 - "Preliminary results of an anticircumsporozoite DNA vaccine trial for protection against avian malaria in captive African black-footed penguins (Spheniscus demersus)."
5.	tafenoquineIBA 01/15/2017 - "Artesunate-tafenoquine combination therapy promotes clearance and abrogates transmission of the avian malaria parasite Plasmodium gallinaceum." 01/15/2017 - "The objectives of this study were to evaluate the efficacy of a relatively new antimalarial compound, tafenoquine (TQ), and a combination of TQ and a low dose of artesunate (ATN) on the in vivo blood stage multiplication, gametocyte development and transmission of the avian malaria parasite Plasmodium gallinaceum to the vector Aedes aegypti. "
6.	Chloroquine (Aralen)FDA LinkGeneric 11/01/1966 - "Effect of the antimalarial chloroquine on the phospholipid metabolism of avian malaria and heart tissue." 11/01/2006 - "All animals had been prophylactically treated for avian malaria, aspergillosis, and possible bacterial infections with chloroquine, itraconazole, and enrofloxacin. " 06/01/2014 - "The efficacy of artesunate, chloroquine, doxycycline, primaquine and a combination of artesunate and primaquine against avian malaria in broilers."
7.	PrimaquineFDA Link 06/01/2014 - "The efficacy of artesunate, chloroquine, doxycycline, primaquine and a combination of artesunate and primaquine against avian malaria in broilers."
8.	Formaldehyde (Formol)FDA Link 09/17/1976 - "Gametocyte infectivity and oocyst development of the avian malaria parasite, Plasmodium gallinaceum, can be reduced or eliminated in mosquitoes by immunizing the chickens on which the mosquitoes feed with infected red blood cells that have been treated with formalin or x-rays. "
9.	Doxycycline (Periostat)FDA LinkGeneric 06/01/2014 - "The efficacy of artesunate, chloroquine, doxycycline, primaquine and a combination of artesunate and primaquine against avian malaria in broilers."
10.	proguanil drug combination atovaquone (malarone)FDA Link 11/09/2023 - "A Safe and Effective Atovaquone-Proguanil Therapeutic Protocol for the Treatment of Avian Malaria by Plasmodium relictum in Snowy Owl (Bubo scandiacus)."

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 08/01/1948 - "The chemotherapy and immunology of preerythrocytic stages in avian malaria." 12/01/1947 - "The chemotherapy and immunology of pre-erythrocytic stages in avian malaria." 12/01/1946 - "The use of avian malaria for the discovery of drugs effective in the treatment and prevention of human malaria; drugs for causal prophylaxis and radical cure or the chemotherapy of exo-erythrocytic forms." 02/01/1955 - "Chemotherapy of avian malarias: III. Trial of certain standard antimalarials on Plasmodium hexamerium and P. "
2.	Therapeutics 07/01/1985 - "The correlation of this symptom with haemolytic or other secondary anaemia is discussed and its value in field outbreaks of avian malaria as an indicator of the need for immediate therapy is emphasised." 01/15/2017 - "Artesunate-tafenoquine combination therapy promotes clearance and abrogates transmission of the avian malaria parasite Plasmodium gallinaceum."
3.	Lasers (Laser) 12/01/2016 - "Laser capture microdissection microscopy and genome sequencing of the avian malaria parasite, Plasmodium relictum."
4.	Diet Therapy (Therapy, Diet) 10/01/1946 - "A comparison of drug-diet therapy with single daily oral dosage in avian malaria."
5.	Decompression 08/01/1979 - "Surface membrane vesicles of red cells infected with the avian malaria Plasmodium lophurae were produced by nitrogen decompression. "