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Waldenstrom Macroglobulinemia (Macroglobulinemia)

A lymphoproliferative disorder characterized by pleomorphic B-LYMPHOCYTES including PLASMA CELLS, with increased levels of monoclonal serum IMMUNOGLOBULIN M. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include ANEMIA; HEMORRHAGES; and hyperviscosity.
Also Known As:
Macroglobulinemia; Waldenstrom's Macroglobulinemia; Familial Waldenstrom's Macroglobulinaemia; Lymphoma, Lymphocytic, Plasmacytoid; Primary Macroglobulinemia; Waldenstrom's Macroglobulinaemia; Familial Waldenstrom Macroglobulinaemia; Familial Waldenstroms Macroglobulinaemia; Lymphomas, Lymphoplasmacytoid; Lymphoplasmacytoid Lymphoma; Lymphoplasmacytoid Lymphomas; Macroglobulinaemia, Familial Waldenstrom's; Macroglobulinaemia, Waldenstrom's; Macroglobulinemia, Primary; Macroglobulinemia, Waldenstrom; Macroglobulinemia, Waldenstrom's; Waldenstrom Macroglobulinaemia; Waldenstrom's Macroglobulinaemia, Familial; Waldenstroms Macroglobulinaemia; Waldenstroms Macroglobulinemia; Lymphoma, Lymphoplasmacytoid
Networked: 1173 relevant articles (63 outcomes, 101 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Multiple Myeloma
2. Lymphoma (Lymphomas)
3. Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
4. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
5. Hairy Cell Leukemia

Experts

1. Treon, Steven P: 72 articles (08/2015 - 04/2003)
2. Ghobrial, Irene M: 54 articles (09/2015 - 11/2003)
3. Leleu, Xavier: 32 articles (11/2015 - 05/2006)
4. Patterson, Christopher J: 29 articles (07/2014 - 03/2005)
5. Gertz, Morie A: 27 articles (10/2015 - 01/2002)
6. Hunter, Zachary R: 27 articles (10/2014 - 03/2005)
7. Roccaro, Aldo M: 26 articles (02/2015 - 03/2008)
8. Sacco, Antonio: 25 articles (06/2014 - 08/2007)
9. Anderson, Kenneth C: 25 articles (08/2013 - 04/2003)
10. Dimopoulos, Meletios A: 23 articles (11/2015 - 05/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Waldenstrom Macroglobulinemia:
1. rituximab (Mabthera)FDA Link
2. fludarabineIBA
3. Cyclophosphamide (Cytoxan)FDA LinkGeneric
4. Dexamethasone (Maxidex)FDA LinkGeneric
5. CladribineFDA LinkGeneric
6. bortezomib (Velcade)FDA Link
7. Chlorambucil (Leukeran)FDA Link
8. Prednisone (Sone)FDA LinkGeneric
9. Pentostatin (Nipent)FDA LinkGeneric
10. Prednisolone (Predate)FDA LinkGeneric

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Plasmapheresis
3. Stem Cell Transplantation
4. Splenectomy
5. Plasma Exchange