Lymphocytosis

08/01/1999 - "Detection of lymphocytosis in peripheral blood, heterophilic antibodies, and the characteristic mononuclear cells by means of specialized blood counters, together with the clinical signs, have improved the quality of diagnosis in emergency services (93% sensitivity and 97.2% specificity). "
06/08/2021 - "The NCWS group showed a longer duration of symptoms, a higher frequency of positive serum anti-nuclear antibodies than CD and IBS patients, and a higher frequency of DQ2/DQ8 haplotypes and duodenal mucosa lymphocytosis than IBS controls. "
12/21/2015 - "Bronchoalveolar lavage differential cell count showed 35% lymphocytosis, and precipitating antibodies for Wallemia sebi, Trichoderma species and Cladosporium sphaerospermum were identified. "
06/01/2002 - "The diagnosis is established by documented exposure, compatible clinical presentation, and consistent radiologic features; it is supported by positive precipitating antibodies, lymphocytosis in bronchoalveolar lavage fluid, and characteristic histologic changes on lung biopsy. "
03/01/1995 - "CSF examination showed lymphocytosis with blastic cells and antibodies against HTLV-I/II."

07/01/2014 - "Clinically, the furthest in development is ibrutinib (trade name, Imbruvica), an irreversible BTKi, which has shown spectacular preliminary efficacy, with rapid reductions in lymph nodes accompanied by peripheral blood lymphocytosis. "
01/01/2019 - "In patients with CLL treated with single-agent ibrutinib in two multicenter, open-label, randomized, phase 3 studies (RESONATE-2, NCT01722487; RESONATE, NCT01578707), lymphocytosis was observed in 77 of 136 (57%) patients treated in first-line and 133 of 195 (69%) relapsed/refractory patients. "
01/01/2019 - "Our findings support that mutational analysis should be considered in patients receiving ibrutinib who have residual clonal lymphocytosis, and that clinical trials are needed to evaluate whether patients with a BTK mutation may benefit from an early switch to another treatment."
01/01/2016 - "In a previous phase 2 study with single-agent ibrutinib, the proportion of patients who achieved an objective response was 68%; 38 (34%) of 111 patients had transient lymphocytosis. "
05/31/2022 - "Recent evidence suggests T-cell enhanced expansion, rather than increased egress from secondary lymphoid organs (SLO), as a root cause for ibrutinib-induced lymphocytosis. "

01/01/2022 - "The BAL lymphocytosis consisted of T cells, while the mean CD4/CD8 ratio was 1.80 in non-steroid- treated patients and 1.14 in steroid-treated patients. "
07/01/2006 - "There were, however, two statistically significant differences between the two groups: (1) only patients with BAL lymphocytosis had to be treated with steroids (5/12 vs. 0/10, P < 0.05) and (2) only patients with BAL lymphocytosis had died in the mean time (6/12 vs. 0/10, P < 0.01). "
08/01/2003 - "Lymphocytosis did not recur after the discontinuation of steroids. "
07/01/1995 - "After steroid treatment almost all these findings returned to normal; only lymphocytosis remained. "
07/01/1993 - "Despite the absence of respiratory symptoms and disappearance of chest radiographic abnormalities on prolonged steroid treatment, we found slow improvement of pulmonary functions associated with persistence of BAL lymphocytosis and elevated CD4+/CD8+ ratios. "

08/01/2002 - "This preliminary study shows that the association of NTX further amplifies the lymphocytosis obtained by IL-2 plus MLT. "
08/01/2002 - "This preliminary study was carried out to evaluate whether the association of NTX may further enhance the lymphocytosis induced by the neuroimmunotherapy with IL-2 plus MLT. "
09/01/2007 - "In order to obtain activated lymphocytosis at the time of operation administration of IL-2 (6 million I.U. "
12/01/2004 - "High-dose, continuous infusion interleukin-2 (IL-2) regimens generate greater Lymphokine Activated Killer cell (LAK) cytotoxicity in vitro and a higher rebound lymphocytosis in vivo than do bolus IL-2 regimens. "
05/01/1999 - "The pretreatment excess of these serum inflammatory markers seems to negatively influence both the host and tumour response to IL-2 administration, by preventing the IL-2-induced lymphocytosis and resulting in tumour progression. "

08/08/2023 - "In this study, we determined if B lymphocytosis may serve as a JDM biomarker for disease activity. "
12/01/2007 - "Monoclonal B-cell lymphocytosis as a biomarker in environmental health studies."
04/20/2021 - "BAL lymphocytosis may provide a predictive biomarker for identifying patients with iNSIP, iPPFE and unclassifiable IIP who are likely to benefit from anti-inflammatory drugs."
11/01/2017 - "However, biomarkers to predict lymphocytosis or successful TFR are not well characterized. "
01/01/2016 - "Reduced blood CD4/CD8 ratio, increased blood CD8 count, and lymphocytosis were additional biomarkers highly correlated with flow cytometry-measured large granular lymphocyte expansions. "

10/01/2002 - "In this study, we showed that administration of neutralizing anti-TRAIL mAb markedly increased serum auto-Ab levels, particularly of IgG1 subclass, in autoimmune-prone C3H/HeJ gld/gld mice without affecting lymphocytosis and lymphocytes populations. "
05/01/2006 - "A diagnosis of EAA was made on finding a restrictive lung function pattern with gas exchange abnormalities, a predominant lymphocytosis in the bronchoalveolar lavage, diffuse ground-glass opacities in the lower lobes on high-resolution computer tomography, and specific IgG antibody activity to the swimming pool water. "
01/14/1995 - "There was a positive correlation (P < 0.05) between the IgG1 levels and the lymphocyte counts of the seropositive cattle with persistent lymphocytosis."
01/14/1995 - "In addition, the seropositive cattle with persistent lymphocytosis had higher IgG1 levels (P < 0.001), total leucocyte counts (P < 0.001) and lymphocyte counts (P < 0.001), than the cattle in the seropositive group without persistent lymphocytosis and the cattle in the seronegative group. "
08/01/1987 - "Granulocyte-binding IgG was measured in 34 patients with CLL, 13 patients with hairy cell leukaemia, one patient with prolymphocytic leukaemia, two patients with Sézary cell leukaemia, and seven patients with chronic T-cell lymphocytosis who had a predominance of circulating large granular lymphocytes. "

01/01/2019 - "Cerebrospinal fluid studies reveal a lymphocytosis and elevated protein. "
03/01/2022 - "Elevated protein (42.42%) and lymphocytosis (24.24%) were found in the cerebrospinal fluid. "
04/01/2021 - "In CSF mild lymphocytosis (14/16, 87.5%) with low cellularity (40.9±49.7/μL) and elevated proteins (11/16, 77.8%, mean 145.0 mg±159.0/dL) were frequent. "
12/01/2020 - "CSF examination revealed lymphocytosis and elevated protein levels. "
01/01/2020 - "The cerebrospinal fluid (CSF) had lymphocytosis in 5 cases and increased protein in 12 cases. "

02/01/1982 - "After 36 months the DNA binding activity spontaneously improved and the lymphocytosis disappeared. "
10/01/1974 - "In the leukotic cattle these studies were limited to the terminal stages of the disease.A positive correlation was noted between the number of DNA synthesizing lymphocytes and lymphocytosis. "
01/30/2023 - "Diagnosis was confirmed through cerebrospinal fluid (CSF) analysis which revealed lymphocytosis and the presence of VZV DNA on PCR analysis. "
01/01/2023 - "Donor-derivation of the patient's post-transplant clonal lymphocytosis was confirmed by serial chimerism analyses of recipient's blood specimens demonstrating 100% donor DNA. "
07/01/2008 - "The results show that in cattle with BLV-induced leukosis as well as in cattle, which were clinically healthy and unsuspicious at slaughter or at post-mortem, either with persistent lymphocytosis (PL) or without, BLV proviral DNA could be detected easily in samples of lymphatic tissues and in high concordance with serological data. "

01/01/2021 - "We report in this work the efficacy of highly active antiretrovirals (ARVs) alone in the treatment of diffuse infiltrative lymphocytosis syndrome (DILS) without the use of corticosteroids, which appears risky in patients living with HIV. "
05/01/1977 - "Effect of corticosteroids on exercise-induced lymphocytosis."
01/01/1977 - "The possibility is pointed out that a CLL in progress must be suspected when persistent lymphocytosis occurs in a patient with typical PMR, even if initially the response to treatment with corticosteroids suggests that PMR is the sole disorder."
01/01/2020 - "Impact of BAL lymphocytosis and presence of honeycombing on corticosteroid treatment effect in fibrotic hypersensitivity pneumonitis: a retrospective cohort study."
01/01/1989 - "Administration of corticosteroids resulted in reduction of cerebrospinal fluid albumin content and of lymphocytosis in bronchoalveolar lavage. "

12/01/1990 - "We reported a prednisolone effective case of T 8 lymphocytosis. "
03/09/2022 - "Treatment with prednisolone induced lymphocytosis with immunophenotypic and genetic features of mantle cell lymphoma. "
09/01/2021 - "Monoclonal B-cell Lymphocytosis Exacerbated by Prednisolone Therapy for Dermatomyositis."
09/01/2021 - "We experienced a case of non-chronic lymphocytic leukemia type monoclonal B-cell lymphocytosis (MBL) that was exacerbated by increasing prednisolone for dermatomyositis and then improved by decreasing the dosage. "
01/01/2007 - "High-dose prednisolone therapy improved the hemolytic anemia and thrombocytopenia, but not the CD16(+) CD56(-) NK lymphocytosis completely. "

11/01/1999 - "A significant reduction of lymphocytosis, lymphoadenomegaly, and organomegaly was obtained within one month of therapy. "
04/20/2021 - "Conversely, for patients managed without anti-inflammatory therapy (n = 63), the presence or absence of BAL lymphocytosis had no prognostic value. "
04/20/2021 - "Eligible patients were stratified into four groups with and without BAL lymphocytosis and anti-inflammatory therapy to compare overall survival (OS) and changes in lung function. "
04/20/2021 - "However, the impact of bronchoalveolar lavage (BAL) lymphocytosis on the effects of anti-inflammatory therapy has never been evaluated. "
04/01/2021 - "Duodenal lymphocytosis decreases significantly after successful eradication therapy but remains elevated when treatment fails."

04/01/2003 - "Lymphocytosis after the splenectomy was not observed. "
06/01/1997 - "Splenectomy impairs lymphocytosis during maximal exercise."
01/01/1996 - "Spurious post-splenectomy CD4 and CD8 lymphocytosis in HIV-infected patients."
12/01/1995 - "The lymphocytosis was noted 4-242 (median 70) months after splenectomy and persisted almost unchanged in most patients on prolonged follow up (median 50 months). "
12/01/1995 - "Post-splenectomy lymphocytosis."

07/13/2021 - "Thereafter, chemotherapy was initiated, which improved the lymphocytosis. "
01/02/2013 - "Eight months later, general symptoms occurred along with lymphocytosis and exacerbation of lesions in lymph nodes, and therefore, chemotherapy was started according to COP regimen. "
08/07/2008 - "Among 185 subjects presenting with lymphocytosis, progressive lymphocytosis occurred in 51 (28%), progressive CLL developed in 28 (15%), and chemotherapy was required in 13 (7%). "
01/01/1999 - "Non-chemotherapy modulation of malignant lymphocytosis."
08/01/1997 - "After the first course of chemotherapy, the lymphocytosis showed a sharp decline to normal absolute cell numbers and subsequently remained at normal levels. "

02/01/2022 - "Although reactive large granular lymphocytosis due to diverse etiologies is not an uncommon finding in clinical practice, isolated natural killer (NK)-cell lymphocytosis is unusual and its association with immunotherapy has not been described thus far. "
09/01/1998 - "The absence of prior treatment with immunotherapy, the total dose of IL-2 administered, and the maximal rebound lymphocytosis after cessation of IL-2 correlated with achieving a complete response. "
08/01/2002 - "Since the lymphocytosis represents the most important favourable prognostic variable predicting the anticancer efficacy of IL-2 immunotherapy, it is probable that a cancer neuroimmunotherapy with IL-2 plus both MLT and NTX to activate TH1 and suppress TH2 cells respectively, may deserve more promising results in the treatment of human neoplasms according to the psychoneuroimnunological knowledge."
01/01/2020 - "We report a fatal immune-mediated adverse events' storm in a thymoma patient treated with Pembrolizumab, leading to hepatotoxicity accompanied by lymphocytosis, thrombocytopenia, and thyroid dysfunction, unveiling a novel potential pathophysiological effect of immunotherapy. "
01/01/2000 - "Lymphocytosis is the main biomarker predicting the efficacy of subcutaneous IL-2 anticancer immunotherapy. "

04/01/2008 - "Therefore, evidence of brain irradiation-induced lymphocytosis may predict the efficacy of radiotherapy."
12/01/1987 - "This treatment is most advisable for elderly patients with predominant bone marrow lymphocytosis, for patients with previous extensive chemotherapy or radiotherapy, and for patients with poor marrow reserve. "
10/01/1976 - "Although a group of 26 patients in continuous complete remission from 12 to 111 mo after radiation treatment regained normal total numbers of lymphocytes and monocytes, they exhibited a striking T lymphocytopenia and B lymphocytosis. "
01/01/2019 - "Monoclonal B-cell lymphocytosis and prostate cancer: incidence and effects of radiotherapy."
08/19/2016 - "T-cell lymphocytosis was relived after surgical and radiation therapy to the metastasis. "