|4.||Lymphatic Diseases (Lymphadenopathy)
|1.||Langerak, Anton W: 6 articles (01/2015 - 06/2007)|
|2.||Orfao, Alberto: 6 articles (01/2015 - 06/2007)|
|3.||Almeida, Julia: 6 articles (01/2015 - 10/2004)|
|4.||Morabito, Fortunato: 4 articles (03/2015 - 01/2008)|
|5.||Molica, Stefano: 4 articles (03/2015 - 07/2004)|
|6.||González, Marcos: 4 articles (01/2015 - 06/2007)|
|7.||Balanzategui, Ana: 4 articles (01/2015 - 10/2004)|
|8.||Troussard, X: 4 articles (10/2011 - 01/2001)|
|9.||Ruiz-Cabello, Francisco: 4 articles (03/2011 - 06/2007)|
|10.||Lima, Margarida: 4 articles (02/2008 - 06/2002)|
08/01/1999 - "Detection of lymphocytosis in peripheral blood, heterophilic antibodies, and the characteristic mononuclear cells by means of specialized blood counters, together with the clinical signs, have improved the quality of diagnosis in emergency services (93% sensitivity and 97.2% specificity). "
01/01/2015 - "Bronchoalveolar lavage differential cell count showed 35% lymphocytosis, and precipitating antibodies for Wallemia sebi, Trichoderma species and Cladosporium sphaerospermum were identified. "
12/01/2002 - "Anti-phospholipid/cofactor antibodies in three cases of persistent polyclonal B lymphocytosis."
06/01/2002 - "The diagnosis is established by documented exposure, compatible clinical presentation, and consistent radiologic features; it is supported by positive precipitating antibodies, lymphocytosis in bronchoalveolar lavage fluid, and characteristic histologic changes on lung biopsy. "
03/01/1995 - "CSF examination showed lymphocytosis with blastic cells and antibodies against HTLV-I/II."
08/01/2002 - "This preliminary study shows that the association of NTX further amplifies the lymphocytosis obtained by IL-2 plus MLT. "
08/01/2002 - "This preliminary study was carried out to evaluate whether the association of NTX may further enhance the lymphocytosis induced by the neuroimmunotherapy with IL-2 plus MLT. "
09/01/2007 - "In order to obtain activated lymphocytosis at the time of operation administration of IL-2 (6 million I.U. "
12/01/2004 - "High-dose, continuous infusion interleukin-2 (IL-2) regimens generate greater Lymphokine Activated Killer cell (LAK) cytotoxicity in vitro and a higher rebound lymphocytosis in vivo than do bolus IL-2 regimens. "
05/01/1999 - "The pretreatment excess of these serum inflammatory markers seems to negatively influence both the host and tumour response to IL-2 administration, by preventing the IL-2-induced lymphocytosis and resulting in tumour progression. "
07/01/2006 - "There were, however, two statistically significant differences between the two groups: (1) only patients with BAL lymphocytosis had to be treated with steroids (5/12 vs. 0/10, P < 0.05) and (2) only patients with BAL lymphocytosis had died in the mean time (6/12 vs. 0/10, P < 0.01). "
08/01/2003 - "Lymphocytosis did not recur after the discontinuation of steroids. "
01/01/2013 - "With initiation of steroids, the transaminitis improved despite increasing eosinophilia and development of an atypical lymphocytosis. "
05/01/1989 - "One patient treated with steroid therapy had reversal of lymphocytosis and severe neutropenia, which both recurred after steroids were withdrawn. "
08/01/1985 - "The lymphocytosis and neutropenia recurred when steroids were withdrawn. "
|4.||Immunoglobulin G (IgG)IBA
10/01/2002 - "In this study, we showed that administration of neutralizing anti-TRAIL mAb markedly increased serum auto-Ab levels, particularly of IgG1 subclass, in autoimmune-prone C3H/HeJ gld/gld mice without affecting lymphocytosis and lymphocytes populations. "
05/01/2009 - "Selective defect of anti-pneumococcal IgG in a patient with persistent polyclonal B cell lymphocytosis."
05/01/2006 - "A diagnosis of EAA was made on finding a restrictive lung function pattern with gas exchange abnormalities, a predominant lymphocytosis in the bronchoalveolar lavage, diffuse ground-glass opacities in the lower lobes on high-resolution computer tomography, and specific IgG antibody activity to the swimming pool water. "
01/14/1995 - "There was a positive correlation (P < 0.05) between the IgG1 levels and the lymphocyte counts of the seropositive cattle with persistent lymphocytosis."
01/14/1995 - "In addition, the seropositive cattle with persistent lymphocytosis had higher IgG1 levels (P < 0.001), total leucocyte counts (P < 0.001) and lymphocyte counts (P < 0.001), than the cattle in the seropositive group without persistent lymphocytosis and the cattle in the seronegative group. "
|5.||DNA (Deoxyribonucleic Acid)IBA
02/01/1982 - "After 36 months the DNA binding activity spontaneously improved and the lymphocytosis disappeared. "
10/01/1974 - "In the leukotic cattle these studies were limited to the terminal stages of the disease.A positive correlation was noted between the number of DNA synthesizing lymphocytes and lymphocytosis. "
07/01/2008 - "The results show that in cattle with BLV-induced leukosis as well as in cattle, which were clinically healthy and unsuspicious at slaughter or at post-mortem, either with persistent lymphocytosis (PL) or without, BLV proviral DNA could be detected easily in samples of lymphatic tissues and in high concordance with serological data. "
07/01/2005 - "BAL analysis showed hypercellularity (n = 6) and/or lymphocytosis (n = 6), and human herpesvirus-8 DNA was detected in two out of two cases. "
02/01/2005 - "These findings suggest that pulmonary lymphocytosis can occur in a subset of HTLV-I carriers without HAM/TSP and that the increased HTLV-I proviral DNA load may be implicated in the pathogenesis of pulmonary involvement in HTLV-I carriers."
|6.||dasatinib (BMS 354825)FDA Link
07/01/2014 - "In order to answer this question, the aim of our study was to determine the frequency of PE and lymphocytosis among our CML patients receiving second-line dasatinib, and to compare the responses and outcomes between patients with or without PE. "
09/01/2013 - "The present study suggested that lymphocytosis in dasatinib-treated CML patients is at least partly associated with a direct effect of dasatinib to stimulate the proliferation of NK cells. "
01/01/2009 - "In summary, the present study suggests that natural killer or natural killer/T cell lineage large granular lymphocyte lymphocytosis develops in association with dasatinib therapy and that large granular lymphocyte might have a therapeutic effect on Ph(+) leukemic cells."
10/01/2015 - "These results demonstrate that immunological condition at diagnosis may affect LGL lymphocytosis in some dasatinib-treated patients. "
10/01/2015 - "LGL lymphocytosis was observed in half of the dasatinib-treated cases (LGL+ group), showing a relation to increased achievement of complete cytogenetic response within 6 months. "
|7.||T-Cell Antigen Receptors (T-Cell Receptor)IBA
02/01/1988 - "[T8 lymphocytosis with rearrangement of the gene for the beta chain of the T cell receptor is found in a case of AMMoL in remission]."
12/01/2008 - "Recent studies suggest the potential involvement of common antigenic stimuli on the ontogeny of monoclonal T-cell receptor (TCR)-alphabeta(+)/CD4(+)/NKa(+)/CD8(-/+dim) T-large granular lymphocyte (LGL) lymphocytosis. "
05/01/1994 - "To examine persistent CD3-large granular lymphocytosis (LGL) cases for clonality, both by lineage specific (T cell receptor) and lineage independent (X-inactivation) molecular methods; and to find out whether X-inactivation studies are more appropriate than gene rearrangement studies for this subset of LGL disorders. "
01/01/2009 - "Further laboratory examination revealed severe neutropaenia, relative lymphocytosis and a clonally rearranged T-cell receptor. "
02/01/2006 - "No T-cell receptor (TCR) genes rearrangement; (5) EB virus antibody usually positive; (6) No unique karyotypic abnormality, sometimes del (6) (q21q25); (7) Exclusion of other diseases with large granular lymphocytosis."
03/01/2000 - "To study the association of polyclonal B-cell lymphocytosis with binucleated lymphocytes with clinical manifestations suggesting the existence of an immunodeficiency, to evaluate the effect of cigarette smoking on this 'benign lymphoid proliferation', to analyze the clonality of lymphocytes, to determine the levels of immunoglobulins (Ig) G, A, M. "
07/02/2009 - "MBL in subjects with lymphocytosis require treatment at a rate of 1.1% per year and present immunoglobulin (IG) gene features and similar to good prognosis CLL. "
06/01/1990 - "Expansion of B lymphocytes with an unusual immunoglobulin rearrangement associated with atypical lymphocytosis and cigarette smoking."
11/30/1989 - "Direct immunofluorescence and fluorescence-activated cell sorter techniques were used for the detection of surface immunoglobulin positive (SIg+) cells in peripheral blood lymphocytes (PBL's) of bovine leukaemia virus (BLV) infected cattle with or without persistent lymphocytosis (PL+, PL-) and in BLV-free cattle. "
12/01/1988 - "Based on the widely believed notion that depression of suppressor T lymphocyte functions is one of the important mechanisms underlying systemic JRA, the activated T lymphocytosis with the suppressor phenotype and suppressive function on the immunoglobulin production may have been related to the improvement of active JRA in the patient."
|9.||Epinephrine (Adrenaline)FDA LinkGeneric
12/01/2000 - "In the present study, epinephrine infusion was used to induce lymphocytosis before immunomagnetic methods were applied to isolate CD16+/-CD56+ and CD16+CD56- CD3- NK cells. "
01/01/2016 - "HIGH caused the greatest lymphocytosis, adrenaline and cardiovascular response (P < 0.05). "
07/01/1992 - "An elevated serum concentration of adrenaline is followed by lymphocytosis in peripheral blood even in splenectomized patients. "
06/01/1990 - "Findings in both groups of patients mimicked the results of parenteral epinephrine administration: a pan-B and -T lymphocytosis with marked increase in CD56 (fourfold to fivefold) and CD8 cells (threefold to fourfold) as well as moderate increases in CD20 and CD4 cells (twofold), resulting in a decrease in the CD4/CD8 ratio compared with control values. "
08/01/1987 - "The lymphocytosis in those not receiving epinephrine may have represented a physiologic reaction to severe stress."
|10.||rituximab (Mabthera)FDA Link
11/01/2001 - "The purpose of this study was to evaluate the AE occurring in patients with malignant B-cell lymphocytosis who received rituximab. "
06/01/2015 - "Recurrence of persistent polyclonal B lymphocytosis (PPBL) after rituximab treatment."
09/01/2002 - "A progressive lymphocytosis developed, which responded to rituximab. "
11/01/2001 - "Rituximab toxicity in patients with peripheral blood malignant B-cell lymphocytosis."
12/01/2013 - "Prompt efficacy of very low-dose rituximab on monoclonal B lymphocytosis in a rheumatoid arthritis patient."
08/01/2014 - "In this large retrospective cohort, we confirmed that splenectomy as first-line treatment in patients with SMZL corrected cytopenias and lymphocytosis within the first year and was associated with a good PFS."
03/01/1986 - "Following splenectomy (without further therapy) the blood lymphocytosis gradually decreased to normal and the patient entered a remission, assigned 42 months after splenectomy by immunological and cytogenetic studies that revealed no cells of clonal origin in blood or bone marrow. "
04/01/2003 - "Lymphocytosis after the splenectomy was not observed. "
06/01/1997 - "Splenectomy impairs lymphocytosis during maximal exercise."
01/01/1996 - "Spurious post-splenectomy CD4 and CD8 lymphocytosis in HIV-infected patients."
|2.||Drug Therapy (Chemotherapy)
01/01/2014 - "Lymphocytosis (>20%) at end of induction chemotherapy had better survival and longer remission.Risk"
01/01/2013 - "Eight months later, general symptoms occurred along with lymphocytosis and exacerbation of lesions in lymph nodes, and therefore, chemotherapy was started according to COP regimen. "
11/01/2011 - "After chemotherapy, the lymphocytosis and the adenopathies disappear and the renal function improve. "
08/07/2008 - "Among 185 subjects presenting with lymphocytosis, progressive lymphocytosis occurred in 51 (28%), progressive CLL developed in 28 (15%), and chemotherapy was required in 13 (7%). "
05/16/2003 - "Because of its benign and indolent course without the need for chemotherapy, it is important to discriminate the disorder of persistent polyclonal B-cell lymphocytosis from other malignant lymphoproliferative diseases."
01/01/2002 - "Not a single histological study of the fetal brain tissues after removal from the axilla showed any signs of graft vs. host or inflammatory reaction (Figures 1-9) but there were features of growth of the transplanted cortical brain tissue along with its different components like neurogenesis, gliogenesis, early neovascularisation and angiogenesis, etc. There was also no systemic leucocytosis or lymphocytosis. "
01/01/2004 - "At 1 month post transplant, asymptomatic large granular lymphocytosis developed. "
01/01/2002 - "There was no unusual leucocytosis, lymphocytosis and the retrieved graft tissue did not suggest transplant rejection. "
12/01/1997 - "Immunological recovery showed persistent CD8+ HLA-DR+ lymphocytosis 8 months after transplant. "
04/01/1995 - "Indications for 27 late OLBs (> 45 days postoperative) included progressive radiologic disease with clinical findings or progressive loss of pulmonary function (18), persistent poor graft function (3), mass or nodules (3), persistent infiltrates without functional loss (2), and persistent lymphocytosis in bronchoalveolar lavage (1). "
09/01/1998 - "The absence of prior treatment with immunotherapy, the total dose of IL-2 administered, and the maximal rebound lymphocytosis after cessation of IL-2 correlated with achieving a complete response. "
08/01/2002 - "Since the lymphocytosis represents the most important favourable prognostic variable predicting the anticancer efficacy of IL-2 immunotherapy, it is probable that a cancer neuroimmunotherapy with IL-2 plus both MLT and NTX to activate TH1 and suppress TH2 cells respectively, may deserve more promising results in the treatment of human neoplasms according to the psychoneuroimnunological knowledge."
01/01/2006 - "This study would suggest that chemotherapy itself may paradoxically act, at least in part, as a cancer immunotherapy by inducing lymphocytosis, as well as previously demonstrated for the only immunotherapy with IL-2, probably by modulating the cytokine network and correcting the altered endogenous production of cytokines, responsible for cancer-related immunodeficiency."
04/01/2008 - "Therefore, evidence of brain irradiation-induced lymphocytosis may predict the efficacy of radiotherapy."
12/01/1987 - "This treatment is most advisable for elderly patients with predominant bone marrow lymphocytosis, for patients with previous extensive chemotherapy or radiotherapy, and for patients with poor marrow reserve. "
01/01/1988 - "The parameters which were measured (body weight, muscular measurement, triceps skinfold creatinine/height index, albumin, transferrin, cholesterol, lymphocytosis), were all significantly lower in patients with radiotherapy enteritis. "