Lymphatic Diseases (Lymphadenopathy)

1.	Rodríguez, Xavier: 1 article (09/2008)
2.	Tortajada, Lidia: 1 article (09/2008)
3.	González, Guadalupe: 1 article (09/2008)
4.	Sentís, Melcior: 1 article (09/2008)
5.	Ganau, Sergi: 1 article (09/2008)
6.	Kocjan, G I: 1 article (08/2008)
7.	Austin, O: 1 article (08/2008)
8.	Lowe, S M: 1 article (08/2008)
9.	Miller, R F: 1 article (08/2008)
10.	Edwards, S G: 1 article (08/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lymphatic Diseases:

1.	Prednisolone (Predate)FDA LinkGeneric 01/01/2006 - "The liver lesions and the lymphadenopathy repeatedly disappeared completely in response to prednisolone pulse therapy while the lesions in the spleen remained practically unchanged. " 09/01/2004 - "With the administration of prednisolone, her symptom and bilateral hilar lymphadenopathy disappeared, and serum ACE level became normal. " 05/01/2004 - "Two months later a cervical lymphadenopathy occurred while recieving treatment with prednisolone. " 05/01/1995 - "Corticosteroid therapy (prednisolone 40 mg/day) resulted in reduction of the cavitary lesions and the lymphadenopathy. " 11/01/1992 - "At 2 months patients who had received prednisolone showed a greater improvement in generalized lymphadenopathy and cough. " Order ALL the reference details at left...
2.	DNA (Deoxyribonucleic Acid)IBA 05/01/1991 - "Previous studies in lupus-prone MRL-lpr/lpr mice treated with 1% DFMO in drinking water have been associated with improved lifespan, and reduced anti-DNA antibody production, lymphadenopathy, and splenic polyamine levels. " 09/15/2002 - "henselae DNA was detected in extirpated lymph nodes only during the first 6 weeks of lymphadenopathy, which indicates that the results of polymerase chain reaction strongly depend on the duration of illness. " 08/01/2000 - "CpG-DNA injection led to local lymphadenopathy characterized by maintenance of cellular composition with some biasing toward elevated dendritic cell composition. " 05/01/2000 - "Comparison of in house polymerase chain reaction with conventional techniques for the detection of Mycobacterium tuberculosis DNA in granulomatous lymphadenopathy." 02/01/1996 - "Diagnostic value of different PCR assays for the detection of mycobacterial DNA in granulomatous lymphadenopathy." Order ALL the reference details at left...
3.	AntibodiesIBA 05/01/1999 - "Dogs were included in the study if they had hilar lymphadenopathy documented radiographically and bronchoscopically, had serum antibodies against Histoplasma capsulatum, and did not have organisms in any cytologic or histologic samples. " 01/01/2004 - "MATERIALS AND METHODS: Sera of 820 persons, including 765 healthy forest workers (group I) and 55 patients with lymphadenopathy (group II) admitted to the Department of Infectious and Neuroinfectious Diseases, Medical Academy, Białystok, were diagnosed for antibodies against F. " 01/01/2002 - "Bartonella henselae specific antibodies were detected in 146 (57.0%) patients with lymphadenopathy. " 08/01/2000 - "Immunoblotting with 724 sera of patients suffering from lymphadenopathy and 100 healthy controls indicated specific FlaA antibodies in 3.9% of the patients' sera but in none of the controls. " 05/05/1997 - "It is recommended that examination for chronic lymphadenopathy includes questions about cat contact and testing for antibodies against Bartonella henselae." Order ALL the reference details at left...
4.	AutoantibodiesIBA 08/01/2004 - "As expected, deficiency for IFN-RII protected MRL/lpr mice from the development of significant autoimmune-associated lymphadenopathy, autoantibodies, and renal disease. " 06/15/1996 - "Our results show that the MRL-lpr beta transgenic strain has increased survival, lower titers of autoantibodies, and decreased lymphadenopathy compared with nontransgenic littermates. " 06/15/1996 - "The lpr mutation, a disruption of the fas gene, induces spontaneous autoimmunity characterized by high titers of autoantibodies, lymphadenopathy, autoreactive T cells, and early mortality. " 12/01/1995 - "Compared with bcl-2-/lpr mice, bcl-2+/lpr showed dramatic increases in lymphadenopathy and T cell accumulation, but not in autoantibodies or B cell numbers. " 12/01/1995 - "The lpr gene encodes a defective form of the fas gene that mediates apoptosis, and its expression results in autoantibodies and massive lymphadenopathy. " Order ALL the reference details at left...
5.	Immunoglobulin G (IgG)IBA 05/01/2008 - "We also report 6 cases of primary lymphadenopathy characterized by increased IgG4+/IgG+plasma cells (mean 58%). " 12/01/2006 - "Patients with hilar lymphadenopathy or lachrymal and salivary gland lesions were found to have significantly higher IgG4 levels than those without (P = 0.0042 and 0.0227, respectively). " 10/01/2004 - "In contrast, high IgG avidity test results were observed only in patients who had developed lymphadenopathy at least 4 months earlier. " 10/01/2004 - "IgG avidity test titers were noted to be time dependent from the clinical onset of lymphadenopathy. " 10/01/2004 - "Evaluation of the immunoglobulin G avidity test for diagnosis of toxoplasmic lymphadenopathy." Order ALL the reference details at left...
6.	Hemoglobins (Hemoglobin)IBA 06/15/1991 - "No significant differences were observed between conventional and aberrant ALL in the distribution of sex, age, leukocyte count, hemoglobin concentration, platelet count, blast count, French-American-British (FAB) type, lymphadenopathy, organomegaly, rate or duration of remission, or survival. " 04/15/1980 - "Factors found to be independently associated with an increased risk of testicular relapse during maintained remission included pretreatment lymphadenopathy, and to a lesser extent, initial hemoglobin level and initial platelet count. " 04/01/2000 - "Univariate analyses showed that presenting features were similar between My+B and My-B with regard to age, sex, race, FAB morphology, white cell count, hemoglobin level, platelet count, liver/spleen size, central nervous system or mediastinal involvement, presence of lymphadenopathy, and proportion of blast cells detected in the marrow. " 02/01/1986 - "However, the E-PT+ patients were also significantly different from the more traditionally-defined E+ patients in that they had lower WBCs and hemoglobin levels, and less frequent lymphadenopathy or mediastinal mass. " 10/01/2000 - "Complete remission is defined as the condition when signs of activity of the disease are absent, splenomegaly and lymphadenopathy are absent, the hemoglobin concentration is > or = 120 g/l, the absolute number of granulocytes is > or = 1.5 x 10(9)/l and the number of thrombocytes is > or = 100 x 10(9)/l. " Order ALL the reference details at left...
7.	Immunoglobulins (Immunoglobulin)IBA 03/01/1984 - "During steroid treatment the general condition improved remarkably and the lymphadenopathy and hepatosplenomegaly decreased, but the T-cell subset proportions and the serum immunoglobulin levels remained unchanged." 04/01/2006 - "The plasma cell variant (10 % of cases), localised or multicentric, is generally aggressive, and occurs in older patients with generalised lymphadenopathy, hepatosplenomegaly, systemic symptoms, anaemia, elevated inflammatory indices, and a polyclonal rise in immunoglobulins. " 03/01/2001 - "Further, HMG reduced significantly the degree of lymphadenopathy and the serum level of immunoglobulin (Ig) G2a anti-dsDNA specific auto-antibody, even at 12 weeks of age. " 07/01/1998 - "Hepatosplenomegaly, chronic lymphadenopathy, and elevated levels of immunoglobulins G and M were also present. " 01/06/1991 - "Lymphadenopathy, the decrease of the immunoglobulin levels and autoantibody titer in the serum, as well as the predominance of monoclonal immunoglobulins point to the possibility of malignant transformation. " Order ALL the reference details at left...
8.	Prednisone (Sone)FDA LinkGeneric 06/01/1986 - "Each patient was treated with prednisone, with improvement or resolution of pulmonary symptoms, hepatosplenomegaly, lymphadenopathy, and growth failure. " 12/01/1981 - "Both are alive at 5.5 and 2.5 years, respectively, after diagnosis, although the latter patient has required intermittent prednisone for recurrent lymphadenopathy. " 11/01/1975 - "Costal cartilage (biopsy) from a 13-year-old boy receiving prolonged prednisone treatment (discontinuously from 2 6/12 to 13 11/12 years) for hepatosplenomegaly and lymphadenopathy has been studied and compared with costal cartilage from untreated individuals. " 02/27/2002 - "RESULTS: Six months after the transplant, the patient developed non-tender cervical lymphadenopathy 2 days after a reduction in prednisone dosage. " 05/01/2002 - "Hodgkin's lymphadenopathy developed 2 wk after prednisone therapy for the nephrotic syndrome had been discontinued. " Order ALL the reference details at left...
9.	Cyclophosphamide (Cytoxan)FDA LinkGeneric 06/01/1984 - "Sinus histiocytosis with massive lymphadenopathy: response to cyclophosphamide therapy." 07/01/2008 - "BACKGROUND: A 74-year-old woman with a history of type I cryoglobulinemia with glomerulonephritis that had been successfully treated with plasmapheresis and cyclophosphamide approximately 9 years earlier presented with hemoptysis and mediastinal lymphadenopathy. " 01/01/1983 - "The PAN was cured with corticosteroids and cyclophosphamide and the lymphadenopathy regressed. " 10/01/1985 - "Both lpr/lpr and gld/gld mice and an AILD patient with lymphadenopathy and high myb RNA in peripheral blood cells were treated with cyclophosphamide (CY). " 11/01/1986 - "The effects of LS-2616 on longevity, as well as on development of lymphadenopathy, splenomegaly, glomerulonephritis, and vasculitis, were pronounced and were comparable with those of cyclophosphamide. " Order ALL the reference details at left...
10.	Dexamethasone (Maxidex)FDA LinkGeneric 05/01/2008 - "Here, we present a case report of SHML causing isolated hilar lymphadenopathy with complete remission for more than 6 years, after a short course of high dose steroid (dexamethasone 20 mg daily for 3 days)." 12/01/2008 - "Although the patient had received treatment with dexamethasone for 5 weeks and antibiotic drugs for 6 weeks, the lymphadenopathy and the associated malaise had not improved. " 06/01/2000 - "Initial treatment with intravenous dexamethasone improved the level of consciousness and decreased the facial edema, mediastinal lymphadenopathy, and the effusions on computed tomography of the chest. " 01/01/2005 - "Sinus histiocytosis with massive lymphadenopathy (SHML) prednisone resistant but dexamethasone sensitive." Order ALL the reference details at left...

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 02/15/1989 - "All 3 were female children who had peripheral lymphadenopathy without organomegaly and underwent complete remission with or without chemotherapy. " 10/01/1976 - "The pulmonary lesions, which were thin walled cavities, and the lymphadenopathy resolved completely after two courses of chemotherapy. " 09/01/2001 - "With a diagnosis of ATL-L stage IV, chemotherapy was commenced, which was effective in reducing the generalized lymphadenopathy as well as the cervical mass and restoring the CSF findings to normality. " 01/01/2007 - "The lymphadenopathy and musculoskeletal manifestations all responded well to chemotherapy. " 05/01/1996 - "During the chemotherapy, his lymphadenopathy subsided and his neurologic and mental status improved. " Order ALL the reference details at left...
2.	Aftercare (After-Treatment) 11/01/2006 - "Two months after treatment, the patient showed near complete remission of the lymphadenopathy. " 12/01/1996 - "A complete tumour response was seen in only one patient who presented with midline lymphadenopathy and remains disease-free 46 months after treatment. " 01/01/2009 - "CONCLUSIONS: Lymphadenopathy after treatment of malignancy is not a definitive sign of recurrence. " 01/01/1994 - "Three years after treatment, there was no evidence of recurrence or lymphadenopathy. " 11/01/1992 - "In the patients with SCC, only a few had metastatic lymphadenopathy, and no recalcification occurred after treatment. " Order ALL the reference details at left...
3.	Amputation 02/01/2009 - "A 54-year-old man presented 3 years after digit amputation for ADPAca with new blue nodules on his arm, lymphadenopathy, and a lung nodule; he was diagnosed with and treated for metastatic ADPAca. " 12/01/1976 - "Regional lymphadenopathy persisting for six to twelve weeks after amputation warrants surgical intervention. " 06/01/1995 - "Management by amputation of the distal phalanx of the ring finger, debulking of the axillary lymphadenopathy with adjunctive radiotherapy to the axilla and chemotherapy, have been successful in achieving a prolonged disease free interval and satisfactory hand function." 11/01/2004 - "Routine regional lymphadenectomy at the time of amputation seems unnecessary, but regional lymphadenopathy persisting for 3 months after amputation warrants surgical intervention." 05/01/2009 - "In this study, disabilities of the upper extremities were evaluated according to the following conditions: 1) amputation, 2) joint contracture, 3) diseases of upper extremity, 4) weakness, 5) sensory loss of the finger tips, and 6) vascular and lymphatic diseases. " Order ALL the reference details at left...
4.	Renal Dialysis (Hemodialysis) 10/01/2003 - "A 78-year-old man who was undergoing hemodialysis therapy was admitted to our hospital because of sore throat, remittent cervical lymphadenopathy, and polyarthritis over the preceding 4 weeks. " 01/01/2002 - "[Thoracic lymphadenopathy due to vascular transformation of lymph node sinuses associated with upper limb edema in a chronic hemodialysis patient with congestive heart failure]" 03/01/1999 - "RESULTS: Atelectasis (60%), cardiomegaly (60%), pleural effusion (51%), vascular congestion (44%), parenchymal consolidation (38%), parenchymal scarring-fibrosis (31%), and lymphadenopathy (29%) were the most common CT findings in the thoraces of the long-term hemodialysis patients. " 01/01/2000 - "We believe that amyloid lymphadenopathy is common in uremic patients, and thus designed this study to determine the frequency of this condition in hemodialysis patients, and to assess its types and patterns. " 07/01/1991 - "Both lymphadenopathy and renal failure were improved by successful administration of prednisolone and hemodialysis. " Order ALL the reference details at left...
5.	X-Ray Film 03/01/1982 - "Chemotaxis of PMNs was significantly suppressed by sera from patients with hilar lymphadenopathy and/or pulmonary infiltration compared with those from healthy subjects (P less than 0.001), whereas there was no significant difference between healthy subjects and patients who revealed complete remission on the chest X-ray films. " 09/01/2006 - "A chest X-ray film showed bilateral hilar lymphadenopathy. " 05/01/2005 - "Chest X-ray film showed bilateral hilar lymphadenopathy and multiple nodules in both lungs. " 04/01/2000 - "Chest X-ray films and computed tomographic (CT) scans showed bilateral hilar lymphadenopathy, nodules, multiple small opacities, and reticulo-linear opacities. " 01/01/2000 - "A chest X-ray film and computed tomographic scans disclosed ground-glass shadows in the lower fields of both lungs with mediastinal lymphadenopathy. " Order ALL the reference details at left...

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