Lymecycline

A semisynthetic antibiotic related to TETRACYCLINE. It is more readily absorbed than TETRACYCLINE and can be used in lower doses.

Also Known As:

Lymecycline Hydrochloride; Tetracyclinemethylene Lysine; Hydrochloride, Lymecycline; Lysine, Tetracycline-L-Methylene; Lysine, Tetracyclinemethylene; N Lysinomethyltetracycline; Tetracycline L Methylene Lysine; N-Lysinomethyltetracycline; Tetracycline-L-Methylene Lysine; L-Lysine, N6-((((4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenyl)carbonyl)amino)methyl)-, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-

Networked: 67 relevant articles (9 outcomes, 20 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Alirezai, Mohsen: 3 articles (01/2007 - 01/2003)
2.	Ochsendorf, Falk: 2 articles (03/2010 - 10/2006)
3.	Coutts, Ian: 2 articles (01/2007 - 09/2003)
4.	George, Sheru A: 2 articles (01/2007 - 09/2003)
5.	Roseeuw, Diane I: 2 articles (01/2007 - 09/2003)
6.	Sidou, Farzaneh: 2 articles (01/2007 - 09/2003)
7.	Soto, Pascale: 2 articles (01/2007 - 09/2003)
8.	Castelli, Riccardo: 1 article (05/2022)
9.	Cozzani, Emanuele: 1 article (05/2022)
10.	Micalizzi, Claudia: 1 article (05/2022)

Related Diseases

1.	Acne Vulgaris 01/01/2003 - "Lymecycline 300 mg od is as effective and safe as lymecycline 150 mg bid in the treatment of moderate to severe acne. " 05/01/2022 - "We consider our case to be of particular interest not only because of the very rare concomitant presence of AF and HS but also because AF was induced by lymecycline, a drug commonly used to treat both acne and HS, and described only once as a drug responsible for AF, so it is an aspect that deserves to be considered by the clinician dealing with similar conditions." 01/01/2018 - "Acne fulminans associated with lymecycline intake: a case report." 08/01/2011 - "These results demonstrate the clinical benefit of combining A/BPO with lymecycline in the treatment of moderate to severe acne vulgaris." 01/01/2003 - "We compared the efficacy and safety of lymecycline 300 mg od vs lymecycline 150 mg bid or placebo in the treatment of moderate to severe acne. "
2.	Infections 04/01/1985 - "A clinical, controlled trial was performed to study the effect of prophylaxis with lymecycline and the role of Chlamydia trachomatis and Mycoplasma hominis in postabortal genital infection. " 04/01/1985 - "A clinical, controlled trial was performed to study the effect of prophylaxis with lymecycline and the role of Chlamydia trachomatis and Mycoplasma hominis in postabortal genital infection. " 01/01/1996 - "Of the 51 patients who had clinical signs and symptoms of genital infection at enrolment, 96% (22/23) of those in the azithromycin group were considered cured (n = 18) or improved (n = 4), as compared with 100% (28/28) of those considered cured (n = 22) or improved (n = 6) in the lymecycline group. " 01/01/1996 - "To compare the clinical and microbiological efficacy of azithromycin in curing chlamydial infections in women with that of lymecycline, and with a view of the possibility of minimizing the problem of compliance by means of single-dose administration, 146 women with culture-positive Chlamydia trachomatis infections were randomly assigned to treatment with a 1 g bolus dose of azithromycin or a 10-day course of lymecycline 300 mg twice daily. " 07/01/1986 - "Seventy-five men with gonococcal urethritis were treated with a single oral dose of thiamphenicol, and 88 men with this infection were treated with two 1.5-g oral doses of lymecycline taken 12 hr apart. "
3.	Arthritis (Polyarthritis) 07/01/2003 - "The results of the initial study showed that long term treatment with lymecycline in patients with acute ReA decreased the duration of arthritis in those with Chlamydia trachomatis triggered ReA, but not in other patients with ReA. " 04/01/1978 - "The effect of lymecycline treatment on arthritis in C3H mice produced 5 months previously by i.v. inoculation of Mycoplasma pulmonis was examined. " 04/01/1978 - "Effects of lymecycline on Mycoplasma pulmonis-induced arthritis in mice." 01/01/1991 - "Double-blind, placebo-controlled study of three-month treatment with lymecycline in reactive arthritis, with special reference to Chlamydia arthritis." 07/01/2003 - "No statistically significant differences were found between placebo and lymecycline groups in the development of chronic arthritis, sacroiliitis, or AS. "
4.	Pelvic Inflammatory Disease (Pelvic Inflammatory Diseases) 07/01/1988 - "In a clinical, controlled trial 55 women with a history of pelvic inflammatory disease (PID) undergoing first-trimester abortion were randomized to either lymecycline therapy or placebo. " 07/01/1988 - "Preventive lymecycline therapy in women with a history of pelvic inflammatory disease undergoing first-trimester abortion: a clinical, controlled trial." 07/01/1988 - "To assess the efficacy of prophylactic antibiotics on postabortal infection in women with a history of pelvic inflammatory diseases (PID), 55 such women undergoing 1st-trimester pregnancy termination were randomly assigned to receive either lymecycline therapy or placebo. "
5.	Melkersson-Rosenthal Syndrome 05/01/2004 - "Successful treatment of Melkersson-Rosenthal Syndrome with lymecycline." 05/01/2004 - "We report the case of a 31-year-old woman affected by Melkersson-Rosenthal syndrome, who has been successfully treated with lymecycline, after variable results with steroids alone or combined with antihistamines, sulphasalazine and clofazimine."

Related Drugs and Biologics

1.	Minocycline (Cyclops)
2.	Doxycycline (Periostat)
3.	Tetracycline (Achromycin)
4.	Tetracyclines
5.	Erythromycin (Erycette)
6.	Rifampin (Rifampicin)
7.	Anti-Bacterial Agents (Antibiotics)
8.	Azithromycin (Zithromax)
9.	Steroids
10.	Sulfasalazine (Azulfidine)

Related Therapies and Procedures

1.	Therapeutics
2.	Photochemotherapy (Photodynamic Therapy)
3.	Aftercare (After-Treatment)