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Liposarcoma

A malignant tumor derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (LIPOSARCOMA, MYXOID), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces. (From Dorland, 27th ed; Stedman, 25th ed)
Also Known As:
Dedifferentiated Liposarcoma; Dedifferentiated Liposarcomas; Liposarcomas; Liposarcomas, Dedifferentiated; Liposarcomas, Pleomorphic; Pleomorphic Liposarcoma; Pleomorphic Liposarcomas; Liposarcoma, Dedifferentiated; Liposarcoma, Pleomorphic
Networked: 909 relevant articles (32 outcomes, 89 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Leiomyosarcoma
2. Neoplasms (Cancer)
3. Sarcoma (Soft Tissue Sarcoma)
4. Lipoma (Lipomata)
5. Hemangiosarcoma (Angiosarcoma)

Experts

1. Singer, Samuel: 13 articles (01/2015 - 10/2002)
2. Lazar, Alexander J: 8 articles (08/2015 - 03/2011)
3. Lev, Dina: 8 articles (04/2015 - 03/2010)
4. Antonescu, Cristina R: 8 articles (06/2013 - 08/2003)
5. Mechtersheimer, Gunhild: 7 articles (11/2014 - 06/2002)
6. Coindre, Jean-Michel: 6 articles (11/2015 - 09/2003)
7. Pedeutour, Florence: 6 articles (11/2015 - 07/2004)
8. Pilotti, S: 6 articles (10/2014 - 09/2000)
9. Demetri, George D: 6 articles (09/2014 - 09/2002)
10. Kurokawa, Riki: 6 articles (01/2014 - 07/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Liposarcoma:
1. trabectedin (ecteinascidin 743)IBA
2. IfosfamideFDA LinkGeneric
3. Doxorubicin (Adriamycin)FDA LinkGeneric
4. Dermatofibrosarcoma protuberansIBA
5. TaxoidsIBA
6. zoledronic acid (zoledronate)FDA Link
7. PPAR gammaIBA
8. MicroRNAs (MicroRNA)IBA
9. troglitazone (Rezulin)FDA Link
10. DNA (Deoxyribonucleic Acid)IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Radiotherapy
3. Adjuvant Chemotherapy
4. Combination Drug Therapy (Combination Chemotherapy)
5. Heterologous Transplantation (Xenotransplantation)