A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. HDL lipoproteins, synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport). Their major protein component is APOLIPOPROTEIN A-I. HDL also shuttle APOLIPOPROTEINS C and APOLIPOPROTEINS E to and from triglyceride-rich lipoproteins during their catabolism. HDL plasma level has been inversely correlated with the risk of cardiovascular diseases.
Also Known As:
Lipoproteins, HDL; Heavy Lipoproteins; alpha-1 Lipoprotein; Density Lipoprotein, High; High Density Lipoproteins; Lipoprotein, High Density; Lipoprotein, High-Density; Lipoproteins, Heavy; Lipoproteins, High-Density; alpha Lipoprotein; alpha Lipoproteins; High Density Lipoprotein; High-Density Lipoprotein; High-Density Lipoproteins; alpha-Lipoprotein; alpha-Lipoproteins