Van der Woude syndrome

An autosomal dominant hereditary developmental disorder characterized by pits and/or sinuses of the lower lip, and cleft lip and/or cleft palate (CL/P, CP). It is the most common cleft syndrome. Mutations in the IRF6 gene have been identified. OMIM: 119300

Also Known As:

Cleft lip and-or palate with mucous cysts of lower lip; Lip pit syndrome; Lip-Pit Syndrome

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Multiple Abnormalities: 211
    - Van der Woude syndrome: 54
  - Musculoskeletal Abnormalities: 43
    - Craniofacial Abnormalities: 203
      - Maxillofacial Abnormalities: 10
        Jaw Abnormalities: 10
        Cleft Palate: 2757
        Van der Woude syndrome: 54
  - Stomatognathic System Abnormalities
    - Maxillofacial Abnormalities: 10
      - Jaw Abnormalities: 10
        Cleft Palate: 2757
        Van der Woude syndrome: 54
    - Mouth Abnormalities: 1
      - Cleft Lip: 3330
        Van der Woude syndrome: 54
      - Cleft Palate: 2757
        Van der Woude syndrome: 54
Stomatognathic Diseases: 705
- Mouth Diseases: 98
  - Lip Diseases: 3
    - Cleft Lip: 3330
      - Van der Woude syndrome: 54
  - Mouth Abnormalities: 1
    - Cleft Lip: 3330
      - Van der Woude syndrome: 54
    - Cleft Palate: 2757
      - Van der Woude syndrome: 54
- Jaw Diseases: 15
  - Jaw Abnormalities: 10
    - Cleft Palate: 2757
      - Van der Woude syndrome: 54
- Stomatognathic System Abnormalities
  - Maxillofacial Abnormalities: 10
    - Jaw Abnormalities: 10
      - Cleft Palate: 2757
        Van der Woude syndrome: 54
  - Mouth Abnormalities: 1
    - Cleft Lip: 3330
      - Van der Woude syndrome: 54
    - Cleft Palate: 2757
      - Van der Woude syndrome: 54
Musculoskeletal Diseases: 719
- Musculoskeletal Abnormalities: 43
  - Craniofacial Abnormalities: 203
    - Maxillofacial Abnormalities: 10
      - Jaw Abnormalities: 10
        Cleft Palate: 2757
        Van der Woude syndrome: 54
- Jaw Diseases: 15
  - Jaw Abnormalities: 10
    - Cleft Palate: 2757
      - Van der Woude syndrome: 54
Neoplasms: 1324753
- Cysts: 25757
  - Van der Woude syndrome: 54
Signs and Symptoms Pathological Conditions
- Anatomical Pathological Conditions
  - Cysts: 25757
    - Van der Woude syndrome: 54
Body Regions
- Head
  - Face
    - Mouth
      - Lip
        Van der Woude syndrome: 54
Stomatognathic System
- Mouth
  - Lip
    - Van der Woude syndrome: 54

Lip

Context: Research Results