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Lichen Planus (Lichen Ruber Planus)

An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a "saw-tooth" pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.
Also Known As:
Lichen Ruber Planus; Lichen Rubra Planus
Networked: 1278 relevant articles (85 outcomes, 140 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Psoriasis (Pustulosis Palmaris et Plantaris)
2. Atopic Dermatitis (Atopic Eczema)
3. Pyoderma Gangrenosum
4. Vitiligo
5. Skin Diseases

Experts

1. Ruzicka, Thomas: 5 articles (11/2014 - 07/2003)
2. Wojnarowska, F: 5 articles (06/2010 - 03/2004)
3. Parodi, Aurora: 4 articles (09/2008 - 08/2002)
4. Goh, Chee Leok: 3 articles (09/2014 - 06/2004)
5. Siadat, Amir Hossein: 3 articles (01/2013 - 06/2010)
6. Iraji, Fariba: 3 articles (01/2013 - 06/2010)
7. Asilian, Ali: 3 articles (01/2013 - 06/2010)
8. Hashimoto, Takashi: 3 articles (01/2013 - 01/2012)
9. Ebrahimi, Majid: 3 articles (10/2012 - 07/2010)
10. Nylander, Elisabet: 3 articles (10/2012 - 07/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lichen Planus:
1. Tacrolimus (Prograf)FDA LinkGeneric
2. Cyclosporine (Ciclosporin)FDA LinkGeneric
3. Adrenal Cortex Hormones (Corticosteroids)IBA
4. Thalidomide (Thalomid)FDA Link
5. Enoxaparin (Lovenox)FDA LinkGeneric
6. Griseofulvin (Grifulvin V)FDA LinkGeneric
7. Betamethasone (Celestone)FDA Link
8. AntigensIBA
9. AntibodiesIBA
10. pimecrolimus (Elidel)FDA Link

Therapies and Procedures

1. Transplants (Transplant)
2. Photopheresis
3. Photochemotherapy (Photodynamic Therapy)
4. PUVA Therapy
5. Homologous Transplantation (Allograft)