Leukocyte Disorders

Disordered formation of various types of leukocytes or an abnormal accumulation or deficiency of these cells.

Also Known As:

Disorder, Leukocyte; Disorders, Leukocyte; Leukocyte Disorder

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Sepsis (Septicemia)
2.	Thrombocytopenia (Thrombopenia)
3.	Scleredema Adultorum
4.	Peritonitis
5.	Infections

Experts

1.	Asens, Marc Llort: 1 article (01/2019)
2.	Fagerholm, Susanna Carola: 1 article (01/2019)
3.	Faisal, Imrul: 1 article (01/2019)
4.	Guenther, Carla: 1 article (01/2019)
5.	Harjunpää, Heidi: 1 article (01/2019)
6.	Morris, Stephan W: 1 article (01/2019)
7.	Moser, Markus: 1 article (01/2019)
8.	Savinko, Terhi: 1 article (01/2019)
9.	Tojkander, Sari: 1 article (01/2019)
10.	Uotila, Liisa M: 1 article (01/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Leukocyte Disorders:

1.	IntegrinsIBA 01/01/2019 - "Consequently, a loss of β2-integrin expression or function causes the immunodeficiency disorders, Leukocyte Adhesion Deficiency (LAD) type I and III. LAD-III is caused by mutations in an important integrin regulator, kindlin-3, but exactly how kindlin-3 regulates leukocyte adhesion has remained incompletely understood. " 06/10/2010 - "In the disorder leukocyte adhesion deficiency III (LAD-III), integrins on platelets and leukocytes are expressed but fail to function and this leads to severe bleeding and infections at an early age. "
2.	Losartan (Cozaar)FDA LinkGeneric 03/01/2000 - "Conversely, AT1 receptor inhibition with losartan proved to be ineffective at attenuating postischemic microcirculatory disorders (leukocyte-endothelial interactions, microvascular perfusion failure) and aggravated cellular injury. "
3.	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/01/1992 - "Levels of serum granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with various leukocyte disorders were estimated by enzyme-linked immunosorbent assay (ELISA). "
4.	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/01/1992 - "Levels of serum granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with various leukocyte disorders were estimated by enzyme-linked immunosorbent assay (ELISA). "
5.	Superoxides (Superoxide)IBA 07/01/2001 - "A novel, multifaceted leukocyte disorder-distinguished by defects in shape change, chemotaxis, ingestion, degranulation, superoxide anion production, and bactericidal activity-was established secondary to a defect in Rac2."
6.	Retinaldehyde (Retinal)IBA 11/01/1988 - "Retinal blood velocity in patients with leukocyte disorders."
7.	Proteins (Proteins, Gene)FDA Link 06/01/1989 - "A rare disorder, leukocyte adhesion deficiency, has provided a model for establishing the relationship between the several distinct alpha subunits and the shared common beta subunit of leukocyte adhesion proteins. "
8.	ImmunosorbentsIBA 01/01/1992 - "Levels of serum granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with various leukocyte disorders were estimated by enzyme-linked immunosorbent assay (ELISA). "
9.	EnzymesIBA 01/01/1992 - "Levels of serum granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with various leukocyte disorders were estimated by enzyme-linked immunosorbent assay (ELISA). "
10.	C-Reactive ProteinIBA 12/01/2013 - "The univariate analysis showed that the prognosis of NEC was related to the factors such as sepsis, congenital heart disease, scleredema, peritonitis, metabolic acidosis, hyponatremia, leukocyte disorder, thrombocytopenia, elevated C-reactive protein, and severe abdominal X-ray abnormalities (P<0.05), and the further logistic regression analysis revealed that congenital heart disease, scleredema, and metabolic acidosis were main risk factors for the clinical outcome of NEC (P<0.05). "