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Mast-Cell Leukemia (Leukemia, Mast Cell)

A form of systemic mastocytosis (MASTOCYTOSIS, SYSTEMIC) characterized by the presence of large numbers of tissue MAST CELLS in the peripheral blood without skin lesions. It is a high-grade LEUKEMIA disease with bone marrow smear of >20% MAST CELLS, multi-organ failure and a short survival.
Also Known As:
Leukemia, Mast Cell; Leukemia, Mast-Cell; Leukemias, Mast-Cell; Mast Cell Leukemia; Mast-Cell Leukemias
Networked: 65 relevant articles (3 outcomes, 3 trials/studies) for this Disease, Comments

Relationship Network

Disease Context: Research Results

Related Diseases

1. Mastocytosis (Mast-Cell Disease)
2. Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
3. Myeloid Leukemia (Leukemia, Myelocytic)
4. Testicular Neoplasms (Testicular Cancer)
5. Systemic Mastocytosis

Experts

1. Valent, Peter: 6 articles (10/2013 - 01/2002)
2. Sperr, Wolfgang R: 4 articles (10/2007 - 01/2002)
3. Horny, Hans-Peter: 3 articles (10/2013 - 01/2002)
4. Pardanani, Animesh: 3 articles (04/2012 - 01/2002)
5. Neckers, Len: 3 articles (05/2008 - 02/2004)
6. Sotlar, Karl: 2 articles (10/2013 - 10/2005)
7. Reiter, Andreas: 2 articles (10/2013 - 09/2013)
8. Kajiguchi, Tomohiro: 2 articles (05/2008 - 10/2005)
9. Lechner, Klaus: 2 articles (03/2004 - 01/2002)
10. Metcalfe, Dean D: 2 articles (02/2004 - 08/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Mast-Cell Leukemia:
1. masitinibIBA
2. 17-(allylamino)-17-demethoxygeldanamycin (17AAG)IBA
3. Chemokine CCL5IBA
4. Macrophage Inflammatory ProteinsIBA
5. Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
6. ChemokinesIBA
7. Interleukin-8 (Interleukin 8)IBA
8. CytokinesIBA
9. InterleukinsIBA
10. Protein-Tyrosine Kinases (Tyrosine Kinase)IBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Stem Cell Transplantation
3. Hematopoietic Stem Cell Transplantation
4. Liver Transplantation
5. PUVA Therapy

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