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Hairy Cell Leukemia

A neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia, little or no lymphadenopathy, and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.
Also Known As:
Leukemia, Hairy Cell; Hairy Cell Leukemias; Leukemias, Hairy Cell; Leukemic Reticuloendothelioses; Reticuloendothelioses, Leukemic; Leukemic Reticuloendotheliosis; Reticuloendotheliosis, Leukemic
Networked: 1329 relevant articles (162 outcomes, 116 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
2. Residual Neoplasm
3. BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
4. Infection
5. Splenomegaly

Experts

1. Kreitman, Robert J: 36 articles (12/2015 - 02/2002)
2. Pastan, Ira: 25 articles (12/2015 - 02/2002)
3. Stetler-Stevenson, Maryalice: 11 articles (12/2013 - 05/2006)
4. Saven, Alan: 10 articles (10/2015 - 03/2003)
5. Forconi, Francesco: 10 articles (01/2014 - 11/2004)
6. Arons, Evgeny: 9 articles (12/2013 - 05/2006)
7. Lauria, Francesco: 9 articles (06/2011 - 11/2004)
8. Ravandi, Farhad: 8 articles (12/2015 - 09/2005)
9. Tallman, Martin S: 8 articles (10/2015 - 04/2002)
10. Grever, Michael R: 7 articles (10/2015 - 03/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Hairy Cell Leukemia:
1. CladribineFDA LinkGeneric
2. Interferon-alpha (Interferon Alfa)FDA Link
3. Pentostatin (Nipent)FDA LinkGeneric
4. InterferonsIBA
5. purineIBA
6. rituximab (Mabthera)FDA Link
7. 2-chloro-3'-deoxyadenosineIBA
8. Immunotoxins (Immunotoxin)IBA
9. Adenosine DeaminaseIBA
10. Granulocyte Colony-Stimulating Factor (G-CSF)IBA

Therapies and Procedures

1. Splenectomy
2. Drug Therapy (Chemotherapy)
3. Aftercare (After-Treatment)
4. Retreatment
5. Transplants (Transplant)