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Leiomyosarcoma

A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)
Also Known As:
Epithelioid Leiomyosarcoma; Epithelioid Leiomyosarcomas; Leiomyosarcomas; Leiomyosarcomas, Epithelioid; Leiomyosarcomas, Myxoid; Myxoid Leiomyosarcoma; Myxoid Leiomyosarcomas; Leiomyosarcoma, Epithelioid; Leiomyosarcoma, Myxoid
Networked: 1737 relevant articles (67 outcomes, 148 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Sarcoma (Soft Tissue Sarcoma)
3. Liposarcoma
4. Neoplasm Metastasis (Metastasis)
5. Myxoid Liposarcoma

Experts

1. Hensley, Martee L: 11 articles (04/2015 - 06/2002)
2. Le Cesne, Axel: 10 articles (04/2015 - 11/2005)
3. Yaegashi, Nobuo: 9 articles (10/2014 - 06/2005)
4. Blessing, John A: 9 articles (10/2014 - 01/2002)
5. van de Rijn, Matt: 8 articles (08/2015 - 10/2003)
6. Lee, Cheng-Han: 7 articles (08/2015 - 06/2009)
7. Blay, Jean-Yves: 7 articles (01/2014 - 08/2006)
8. Pollock, Raphael E: 7 articles (07/2013 - 04/2002)
9. Coindre, Jean-Michel: 7 articles (04/2013 - 08/2006)
10. Espinosa, Inigo: 6 articles (08/2015 - 06/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Leiomyosarcoma:
1. gemcitabineFDA Link
2. trabectedin (ecteinascidin 743)IBA
3. Doxorubicin (Adriamycin)FDA LinkGeneric
4. docetaxel (Taxotere)FDA Link
5. IfosfamideFDA LinkGeneric
6. Paclitaxel (Taxol)FDA LinkGeneric
7. temozolomide (Temodar)FDA LinkGeneric
8. bevacizumabFDA Link
9. TaxoidsIBA
10. Estrogens (Estrogen)FDA Link

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Radiotherapy
3. Heterologous Transplantation (Xenotransplantation)
4. Combination Drug Therapy (Combination Chemotherapy)
5. Adjuvant Chemotherapy