Language Development Disorders (Semantic-Pragmatic Disorder)

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113 relevant articles (3 outcomes, 16 trials/studies) found for this Disease

Description: Conditions characterized by language abilities (comprehension and expression of speech and writing) that are below the expected level for a given age, generally in the absence of an intellectual impairment. These conditions may be associated with DEAFNESS; BRAIN DISEASES; MENTAL DISORDERS; or environmental factors.

Also Known As:

Semantic-Pragmatic Disorder; Language Delay; Language Delays; Speech Delay; Auditory Processing Disorder, Central; Central Auditory Processing Disorder; Developmental Disorder, Speech or Language; Developmental Language Disorders; Language Disorders, Developmental; Speech or Language, Developmental Disorder; Delay, Speech; Delays, Speech; Development Disorder, Language; Developmental Language Disorder; Language Development Disorder; Language Disorder, Developmental; Semantic Pragmatic Disorder; Semantic-Pragmatic Disorders; Speech Delays

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3422

Neurologic Manifestations: 2879

Neurobehavioral Manifestations: 298

Communication Disorders: 85

Language Disorders: 74

Language Development Disorders: 113

Signs and Symptoms Pathological Conditions

Signs and Symptoms

Neurologic Manifestations: 2879

Neurobehavioral Manifestations: 298

Communication Disorders: 85

Language Disorders: 74

Language Development Disorders: 113

Related Diseases

1.	Cleft Palate (Palate, Cleft)
2.	Seizures (Seizure)
3.	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
4.	Dyslexia (Alexia)
5.	Apraxias (Dyspraxia)

Experts

1.	Nye, C: 2 articles (01/2003 - 03/2000)
2.	Law, J: 2 articles (01/2003 - 03/2000)
3.	Lundy, Claire T: 1 article (07/2007)
4.	Doherty, Gary M: 1 article (07/2007)
5.	Hicks, Elaine M: 1 article (07/2007)
6.	Item, C B: 1 article (06/2007)
7.	Häusler, M: 1 article (06/2007)
8.	Vokral, Jan: 1 article (06/2007)
9.	Dlouha, Olga: 1 article (06/2007)
10.	Vodopiutz, J: 1 article (06/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Language Development Disorders:

1.	amsonic acid (DAS)IBA 04/01/1997 - "Summed across the three studies, 52% of 48 eligible samples from 53 children with suspected DAS had inappropriate stress, compared to 10% of 71 eligible samples from 73 age-matched children with speech delay of unknown origin" 04/01/1997 - "Study I compares speech and prosody-voice profiles of a group of 14 children with suspected DAS to profiles of 73 children with speech delay (SD)" 12/01/1999 - "The lexical metrical patterns of children with SD-DAS were compared to those of a group of children with speech delay (SD) to verify the applicability of metrical constructs to children with disorders while at the same time seeking lexical stress characteristics that might be useful for differential diagnosis" 04/01/1997 - "Two prior studies in this series (Shriberg, Aram, & Kwiatkowski, 1997a, 1997b) address the premise that children with developmental apraxia of speech (DAS) can be differentiated from children with speech delay (SD) on the basis of one or more reliable differences in their speech" 04/01/1997 - "Developmental apraxia of speech (DAS) is a putative diagnostic category for children whose speech errors presumedly (a) differ from the errors of children with developmental speech delay (SD) and (b) resemble the errors of adults with acquired apraxia of speech" Order ALL the reference details at left...
2.	Temazepam (Nocturne)FDA LinkGeneric 11/01/1989 - "Results of CT/MRI studies suggest that in the brains of dyslexics there is an increased incidence of symmetry in the region of the planum temporale and parietooccipital cortex that may be associated with language delay and handedness" 09/01/1998 - "Using high-resolution magnetic resonance morphometry, we studied 21 right-handed children with developmental language disorder of the phonologic-syntactic type, and found normal left-right asymmetry of the planum temporale and planum parietale when compared with 21 matched controls" 12/01/1997 - "Brain morphology studies of individuals with developmental language disorders report reversed asymmetry or symmetry of the planum, although the bulk of this research has been completed on adults with dyslexia" Order ALL the reference details at left...
3.	Methylphenidate (Ritalin)FDA LinkGeneric 08/01/2000 - "A double-blind, placebo-controlled study was used to investigate the effects of methylphenidate (Ritalin) on tests of auditory processing in children diagnosed with both Attention Deficit Hyperactivity Disorder (ADHD) and Central Auditory Processing Disorder (CAPD)" Order ALL the reference details at left...
4.	Glucose (Dextrose)FDA LinkGeneric 06/30/2007 - "PURPOSE: To investigate the general characteristics of glucose metabolism distribution and the functional deficit in the brain of children with developmental language delay (DLD), we compared functional neuroradiological studies such as positron emission tomography (PET) of a patient group of DLD children and a control group of attention- deficit hyperactivity disorder (ADHD) children" Order ALL the reference details at left...
5.	mofezolac (N 22)IBA 09/01/2000 - "This study on children with a Pervasive Developmental Disorder (PDD; N = 32), children with developmental language disorder (N = 22), and normally developing children (N = 28) sought to answer questions concerning attachment and autistic behaviour" Order ALL the reference details at left...
6.	Aligeron (AS 2)IBA 04/01/2007 - "Cut-off scores, calculated as 2 standard deviations below the mean adjusted for age, were calculated for each performance measure for children ages 6 to 11 yr. These scores, which represent the level below which performance on the LISN-S is considered to be outside normal limits, will be used to in future studies with children with suspected central auditory processing disorder." Order ALL the reference details at left...
7.	dicarboxydine (DCD)IBA 05/01/2007 - "AIM: The present study was conducted to determine whether children who had been identified with speech/language delays as toddlers demonstrated characteristics of DCD and/or speech/language problems at kindergarten age" Order ALL the reference details at left...
8.	Carbon MonoxideIBA 11/01/2007 - "Half of the children with language delay had problems on Bus Story Test Information and on the Narrative Memory subtest independently of co-occurrence of neuropsychiatric disorder" 05/01/2007 - "CONCLUSIONS: Young children who are in early intervention programmes for speech/language delays may have significant co-ordination difficulties that will become more evident at kindergarten age when motor deficits begin to impact self-care and academic tasks" 07/01/2004 - "Results suggest that co-occurrence of attention-behavioural, motor-perceptual, and language delays occurring in school-aged children could already be detected at the age of 4 years" 01/01/2000 - "There is a challenge to the view that disorders in the semantic and pragmatic domains necessarily co-occur, as suggested by the diagnostic category semantic-pragmatic disorder." 12/01/1982 - "Two types of interactions are examined: The co-occurrence of speech and language delay and the effects of phonological reduction on the realization of phonetically complex morphophonemes" Order ALL the reference details at left...
9.	CreatineIBA 09/01/2008 - "MATERIALS AND METHODS: Two siblings, a 7-year-old female presenting with mild psychomotor delay, and a 5-year-old male with severe psychomotor retardation, epilepsy and autistic spectrum of problems including speech delay, underwent MR examination because of suspected creatine deficiency" 04/01/2000 - "We describe a new creatine metabolism disorder in 2 young sisters who suffered from mental retardation and severe language delay" 01/01/2007 - "CRT is essential for normal brain function as mutations in the CRT gene (SLC6A8) result in X-linked mental retardation, associated with the almost complete lack of creatine in the brain, severe speech and language delay, epilepsy, and autistic behaviour" 02/01/2006 - "The clinical phenotype was characterized by severe mental retardation, epilepsy, autism, severe speech delay and absence of brain creatine by MRS" 01/01/2004 - "The creatine deficiency syndromes are underdiagnosed, so their possibility should be considered in all children affected by unexplained mental retardation, seizures and speech delay." Order ALL the reference details at left...
10.	Cocaine (Cocaine HCl)IBA 07/01/2005 - "The child with prenatal exposure to cocaine may be considered at increased risk for language delay or disorder" 09/01/2004 - "Children exposed to cocaine had more mild receptive language delays than nonexposed children and were less likely to have higher expressive abilities" 09/01/2001 - "persistent cognitive, motor and language delays of the cocaine-exposed VLBW children, combined with the poorer behavioral interactions of cocaine-using women with their infants in the neonatal period, indicate a need for increased developmental surveillance of cocaine-exposed VLBW infants with a focus on maternal drug treatment and parenting interventions." 03/01/2000 - "To determine the effects of fetal cocaine exposure independent of postnatal environmental effects, cocaine-exposed neonates would ideally be tested within the first few weeks of birth, and to identify early risks for subsequent language delay, well-researched auditory information processing measures could be used" 02/01/1997 - "Physicians caring for cocaine-exposed children with early language delay should not automatically ascribe the delay to cocaine exposure but should initiate a standard evaluation for language delay." Order ALL the reference details at left...

Therapies and Procedures

1.	Speech Therapy (Therapy, Speech) 05/01/2004 - "The developmental delay, the language delay and frequency of the speech therapy influence the therapy effect" 05/01/2004 - "The logistic multiple stepwise regression analysis showed that the history of the positive developmental delay, language delay and the frequency of the speech therapy were related to the therapy effect" 04/25/2002 - "OBJECTIVE: this article discusses the effect of speech therapy on language comprehension, language production and non-verbal functioning in two groups of children with developmental language disorders" 07/02/2001 - "A Fisher exact test demonstrated that the frequency of mothers from the experimental group that modified their style and mode of interaction was significantly greater as compared to the number of mothers from the control group that were able to modify their style and mode of interaction.CONCLUSIONS: Mothers of children with cleft palate and accompanying language delay modify their communicative style and mode of interaction through active participation in speech therapy." 09/01/2000 - "The purpose of this study was to find out if including the mother as an active participant in speech therapy sessions would improve the language development of children with cleft palate who also had additional language delays" Order ALL the reference details at left...
2.	Middle Ear Ventilation (Tympanostomy) 12/01/1999 - "Many children had speech and language delay, but parents thought this improved after grommet insertion" 01/01/1992 - "Referral for insertion of tympanostomy tubes is most appropriate for patients with documented language delay and/or significant medical complications." 05/01/2004 - "The subcommittee also made recommendations that 4) hearing testing be conducted when OME persists for 3 months or longer or at any time that language delay, learning problems, or a significant hearing loss is suspected in a child with OME, 5) children with persistent OME who are not at risk should be reexamined at 3- to 6-month intervals until the effusion is no longer present, significant hearing loss is identified, or structural abnormalities of the eardrum or middle ear are suspected, and 6) when a child becomes a surgical candidate (tympanostomy tube insertion is the preferred initial procedure)" 05/01/2004 - "The subcommittee also made recommendations that (4) hearing testing be conducted when OME persists for 3 months or longer, or at any time that language delay, learning problems, or a significant hearing loss is suspected in a child with OME; (5) children with persistent OME who are not at risk should be reexamined at 3- to 6-month intervals until the effusion is no longer present, significant hearing loss is identified, or structural abnormalities of the eardrum or middle ear are suspected; and (6) when a child becomes a surgical candidate, tympanostomy tube insertion is the preferred initial procedure" Order ALL the reference details at left...
3.	Hemispherectomy 07/01/1998 - "Continuous unilateral epileptiform discharge and language delay: effect of functional hemispherectomy on language acquisition." 07/01/1998 - "PURPOSE: To assess the efficacy of functional hemispherectomy in promoting language acquisition in a child with severe language delay and continuous left hemispheric epileptiform discharge in the absence of clinical seizures" Order ALL the reference details at left...
4.	Language Therapy (Language Training) 07/01/2003 - "METHODS: The study reports data on 69 children under the age of 3.5 years who were referred for speech and language therapy because of early speech and language delay" 01/01/2003 - "SELECTION CRITERIA: The review considered randomised controlled trials of speech and language therapy interventions for children or adolescents with primary speech and language delay/disorder" 11/01/2002 - "OBJECTIVES: The paper presents a research study investigating the effectiveness and acceptability of community speech and language therapy provision for preschool children with early speech/language delays" 04/01/2001 - "The model suggests that most of the children in the study will reach a level of over 90% sentence recognition in the auditory-visual condition when their language becomes equivalent to that of a normally hearing 7-year-old, but they will enter secondary school at age 12 with an average language delay of about 4 or 5 years unless they receive concentrated and effective language training." 01/01/2003 - "Speech and language therapy interventions for children with primary speech and language delay or disorder." Order ALL the reference details at left...
5.	Continuous Ambulatory Peritoneal Dialysis (CAPD) 06/01/1997 - "The purpose of this study was to determine if there were differences between children identified in a clinical setting as having Central Auditory Processing Disorder (CAPD), an age-matched peer group, and young adults when tested using a vocal reaction time (VRT) format" 06/01/2007 - "The aim of this project is to use central auditory tests for diagnosis of central auditory processing disorder (CAPD) in children with specific language impairment (SLI), in order to confirm relationship between speech-language impairment and central auditory processing" 06/01/2007 - "Central auditory processing disorder (CAPD) in children with specific language impairment (SLI)" 01/01/2007 - "In this review paper, the prevalence and characteristics of central auditory processing disorder (CAPD) are reviewed" 12/01/2005 - "For the past 10 years, Cacace and McFarland have contended that current central auditory processing tests are invalid because they cannot disassociate central auditory processing disorder (CAPD) from language, attention, and other problems" Order ALL the reference details at left...

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