|1.||Kalousová, Marta: 4 articles (03/2015 - 04/2008)|
|2.||Jáchymová, Marie: 4 articles (03/2015 - 04/2008)|
|3.||Antognelli, C: 3 articles (04/2015 - 09/2002)|
|4.||Schalkwijk, Casper G: 3 articles (04/2014 - 01/2011)|
|5.||Zhang, Zhenbo: 3 articles (04/2013 - 02/2011)|
|6.||Zhu, Yaping: 3 articles (04/2013 - 02/2011)|
|7.||Feng, Youji: 3 articles (04/2013 - 02/2011)|
|8.||Dong, Lingling: 3 articles (04/2013 - 02/2011)|
|9.||Antognelli, Cinzia: 3 articles (01/2013 - 03/2006)|
|10.||Miyata, Toshio: 3 articles (01/2013 - 04/2009)|
07/01/1995 - "Thus increased glyoxalase I is associated with the malignant phenotype and may also contribute to protection against the cytotoxicity of certain anti-cancer drugs."
02/26/2015 - "Among these six candidates, GLO1, encoding a detoxifying enzyme glyoxalase I (GLO1), exhibited the strongest tumor-forming activity. "
01/01/2014 - "Glyoxalase I in tumor cell proliferation and survival and as a potential target for anticancer therapy."
02/01/2011 - "Several recent developments suggest that the human glyoxalase I (GLO I) is a potential target for anti-tumor drug development. "
03/01/2005 - "Glyoxalase I activity has been shown to be directly related to cancer and its inhibitors have been used as anti-cancer drugs. "
01/21/2011 - "A significant reduction in both Glyoxalase I and FN3K activity was detected in patients with tumors compared to patients with adenomas and the controls. "
01/21/2011 - "Erythrocyte Glyoxalase I activity in colorectal cancer was approximately 6 times lower than that detected in patients with adenoma (0.022 ± 0.01 mmol/min per milliliter vs 0.128 ± 0.19 mmol/min per milliliter of red blood cells, P = 0.003, Tukey's test). "
01/21/2011 - "To investigate Glyoxalase I and fructosamine-3-kinase (FN3K) activity in red blood cells from patients with colorectal adenomas and cancer. "
12/01/2003 - "Glyoxalase I-mediated drug resistance was found in human leukaemia and lung carcinoma cells. "
01/01/2001 - "Glyoxalase I phenotype as a potential risk factor for prostate carcinoma."
03/15/1993 - "These results suggest induction of the glyoxalase-I gene expression in colon carcinomas."
03/15/1993 - "Examination of colon carcinomas for the amplification of the glyoxalase-I gene by Southern blot analysis revealed no change in gene copy number. "
03/15/1993 - "Northern analysis of the RNA showed an approximately 12-fold increase of the 2.2-kilobase glyoxalase-I transcript in carcinoma when compared to normal colon tissue from the same patient. "
|5.||Genetic Predisposition to Disease (Genetic Predisposition)
04/01/2008 - "In summary, in this study we demonstrate for the first time the association of A419C polymorphism of the glyoxalase I gene with sRAGE levels and show the genetic predisposition to vascular complications in HD patients."
04/27/2005 - "The same phenotype-dependent difference was found in red blood cells with NAB-M and CM-M animals showing intermediate expression profiles of glyoxalase-I. Additional studies will examine whether glyoxalase-I has an impact beyond that of a biomarker to predict the genetic predisposition to anxiety- and depression-like behavior."
07/01/1993 - "With the purpose to study the genetic susceptibility to paracoccidioidomycosis infection we searched for a possible association between glyoxalase I and the intradermic paracoccidioidin reaction. "
|3.||Messenger RNA (mRNA)
|5.||Advanced Glycosylation End Products
|7.||Aldehyde Reductase (Aldose Reductase)
|8.||Complement System Proteins (Complement)
|9.||Pepsinogen A (Pepsinogen)
|10.||Steroid 21-Hydroxylase (21 Hydroxylase)
|1.||Drug Therapy (Chemotherapy)