|1.||Svanborg, Catharina: 30 articles (05/2015 - 01/2003)|
|2.||Mossberg, Ann-Kristin: 19 articles (01/2011 - 01/2003)|
|3.||Gustafsson, Lotta: 10 articles (03/2009 - 01/2003)|
|4.||Permyakov, Eugene A: 6 articles (09/2013 - 05/2004)|
|5.||Trulsson, Maria: 5 articles (10/2012 - 01/2009)|
|6.||Hallgren, Oskar: 5 articles (03/2009 - 01/2003)|
|7.||Linse, Sara: 5 articles (11/2005 - 01/2003)|
|8.||Nadeem, Aftab: 4 articles (05/2015 - 10/2012)|
|9.||Storm, Petter: 4 articles (01/2014 - 01/2009)|
|10.||Permyakov, Sergei E: 4 articles (09/2013 - 12/2008)|
01/01/2015 - "This view emerges from the extraordinary manner in which HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) kills a wide range of tumor cells in vitro and demonstrates therapeutic efficacy and selectivity in cancer models and clinical studies. "
12/30/2015 - "Therefore, in this study, we prepared self-assembled α-lactalbumin that exhibits strong inherent antiproliferative potential in multiple cancer cells which can be used for efficient therapeutic approach in cancer. "
11/01/2015 - "The HAMLET family of compounds (Human Alpha-lactalbumin Made Lethal to Tumours) was discovered during studies on the properties of human milk, and is a class of protein-lipid complexes having broad spectrum anti-cancer, and some specific anti-bacterial properties. "
05/01/2004 - "This study tested the effect of HAMLET (human alpha-lactalbumin made lethal to tumor cells) on mammary cells. "
12/30/2015 - "When compared with a well-known protein-based anticancer agent BAMLET (bovine α-lactalbumin made lethal against tumor cell), the self-assembled BLA clearly exhibited higher cytotoxicity to cancer cells than BAMLET. "
|2.||Breast Neoplasms (Breast Cancer)
07/01/2010 - "Thus, alpha-lactalbumin vaccination may provide safe and effective protection against the development of breast cancer for women in their post-child-bearing, premenopausal years, when lactation is readily avoidable and risk for developing breast cancer is high."
12/01/2005 - "AdE1aALAE1b showed better breast cancer-restricted replication than AdALAE1a, suggesting that a transcriptional targeting modality with alpha-lactalbumin promoter controlling both E1a and E1b gene expression is superior to alpha-lactalbumin promoter controlling only E1a gene expression. "
10/15/1980 - "These findings suggest that IIF for alpha-lactalbumin may be helpful in ascertaining the site of origin of metastatic breast tumors. "
12/01/2005 - "Alpha-lactalbumin promoter showed significantly higher activity in MDA-MB-435S and T47D breast cancer cells than in normal breast cell lines or other tumor cell lines. "
12/01/2005 - "To evaluate the effect of gene therapy for breast cancer by controlling adenovirus replication with human alpha-lactalbumin promoter, we investigated the activity of a 762-bp human alpha-lactalbumin promoter. "
|3.||Weight Loss (Weight Reduction)
06/01/1997 - "However, the test group regained the weight loss after switching to the lactalbumin diet. "
02/01/2011 - "Efficacy of α-lactalbumin and milk protein on weight loss and body composition during energy restriction."
08/01/2009 - "Weight loss by energy restriction was performed on four different high-Ca diets (1.8 % CaCO3) containing different whey proteins (18 % of energy): alpha-lactalbumin (ALA), beta-lactoglobulin (BLG), lactoferrin (LF) and whey protein isolate (WPI). "
|4.||Milk Hypersensitivity (Milk Allergy)
03/01/1991 - "No correlation was found between concentrations of serum IgE and serum alpha-lactalbumin in the children with cows' milk allergy."
06/01/1996 - "The results of this study demonstrate the existence of an IgE-mediated mare's milk allergy caused by low molecular weight heat-labile proteins, most likely alpha-lactalbumin and beta-lactoglobulin, which do not cross-react with the corresponding whey proteins in cow's milk."
12/23/2015 - "α-Lactalbumin and β-lactoglobulin are two major whey proteins that specifically bind immunoglobulin E and are suspected as major allergens causing cow's milk allergy (CMA). "
07/01/2008 - "To investigate the intrinsic properties (as well as the effect of pasteurization) of the milk proteins alpha-lactalbumin, beta-lactoglobulin and casein that promote the induction of milk allergy. "
01/01/2006 - "Prospectively, 45 infants and toddlers with a positive history of cow's milk allergy confirmed by positive skin prick test and high IgE levels for either alpha-lactalbumin, beta-lactoglobulin, or casein and positive single-blind food challenge received extensively hydrolyzed milk formulas for 1 year. "
07/01/2010 - "We selected alpha-lactalbumin as our target vaccine autoantigen because it is a breast-specific differentiation protein expressed in high amounts in the majority of human breast carcinomas and in mammary epithelial cells only during lactation. "
08/01/1999 - "The influence of the ON on the activity of the cytotoxic fraction of human milk alpha-lactalbumin towards human mammary gland carcinoma MCF-7 cells was studied. "
07/01/1998 - "Lactalbumin-positive mammary carcinoma in a mare."
07/01/1992 - "Immunohistochemical staining showed alpha-lactalbumin (alpha-LA) in the lipid-secreting carcinomas at sites exhibiting active lipid secretion. "
03/01/1989 - "In addition, GCDFP-15 was compared with another putative mammary epithelial marker, alpha-lactalbumin (ALA), with respect to sensitivity and specificity for a diagnosis of breast carcinoma. "
|1.||Oleic Acid (Oleate)
|3.||Milk Proteins (Milk Protein)
|6.||Proteins (Proteins, Gene)
|9.||Immunoglobulin E (IgE)
|10.||Bovine Serum Albumin
|1.||Protein-Restricted Diet (Diet, Protein Restricted)
|2.||Investigational Therapies (Experimental Therapy)
|3.||Heterologous Transplantation (Xenotransplantation)
|4.||Photochemotherapy (Photodynamic Therapy)