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Kwashiorkor

A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning "displaced child". Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed)
Also Known As:
Kwashiorkors
Networked: 553 relevant articles (15 outcomes, 37 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Protein-Energy Malnutrition (Marasmus)
2. Malaria
3. Body Weight (Weight, Body)
4. Skin Diseases
5. Cholestasis

Experts

1. Woodward, Bill: 4 articles (05/2012 - 03/2006)
2. Monk, Jennifer M: 4 articles (05/2012 - 03/2006)
3. Heikens, Geert Tom: 3 articles (09/2012 - 11/2010)
4. Mendel, Marijke: 3 articles (09/2012 - 11/2010)
5. Spoelstra, Martijn N: 3 articles (09/2012 - 11/2010)
6. Senga, Edward: 3 articles (09/2012 - 11/2010)
7. Bandsma, Robert H J: 3 articles (09/2012 - 11/2010)
8. Manary, M J: 3 articles (09/2000 - 02/2000)
9. Mari, Andrea: 2 articles (09/2012 - 02/2011)
10. Reijngoud, Dirk-Jan: 2 articles (09/2012 - 11/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Kwashiorkor:
1. Insulin (Novolin)FDA Link
2. Chloramphenicol (Chloromycetin)FDA Link
3. AflatoxinsIBA
4. Amino AcidsFDA Link
5. Immunoglobulins (Immunoglobulin)IBA
6. Glutathione (Reduced Glutathione)IBA
7. OsteocalcinIBA
8. Carotenoids (Carotene)IBA
9. Caffeine (No Doz)FDA LinkGeneric
10. Thioctic Acid (Lipoic Acid)IBA

Therapies and Procedures

1. Enteral Nutrition (Feeding, Tube)
2. Nursing Care
3. Aftercare (After-Treatment)
4. Protein-Restricted Diet (Diet, Protein Restricted)
03/01/1988 - "Low protein diet was given and, thus, the full picture of kwashiorkor developed soon as a logical consequence. "
05/01/2012 - "Male and female C57BL/6J mice, initially 19 d old, consumed a complete purified diet either ad libitum (age-matched controls) or in restricted daily quantities (mimicking marasmus), or consumed an isoenergetic low-protein diet ad libitum (mimicking incipient kwashiorkor) for 14 d (six animals per dietary group). "
03/01/2006 - "Male and female C57BL/6J mice, initially 19 days old, and CBA/J mice, initially 23 days old, consumed a complete purified diet either ad libitum (age-matched control) or in restricted daily quantities (mimicking marasmus), or they consumed a purified isocaloric low-protein diet ad libitum (mimicking incipient kwashiorkor). "
06/01/2001 - "We isolated muscles from 3 groups (n = 5) of weanling C57BL/6J mice of both sexes (i) mice at 19 days of age serving as zero-time or baseline controls (CONT) (ii) mice fed for the next 14 days with a low-protein diet that produces features of incipient kwashiorkor (LPD) and (iii) mice fed for the next 14 days with a complete diet (NORM). "
01/01/2011 - "Weanling mice consumed a complete diet ad libitum, a low-protein diet ad libitum (mimicking incipient kwashiorkor), or the complete diet in restricted daily quantities (mimicking marasmus), and their second-tier IL-10 production was determined both in vitro and in vivo using lipopolysaccharide (LPS) and anti-CD3 as stimulants of innate and adaptive defences, respectively. "
5. Gastrectomy