|3.||Knee Injuries (Knee Injury)
|4.||Wounds and Injuries (Trauma)
|1.||Roos, Ewa M: 9 articles (10/2015 - 01/2003)|
|2.||Lohmander, L S: 7 articles (11/2015 - 04/2009)|
|3.||Struglics, A: 6 articles (11/2015 - 04/2009)|
|4.||Larsson, S: 5 articles (11/2015 - 04/2009)|
|5.||Roos, E M: 5 articles (09/2015 - 04/2007)|
|6.||Kaeding, Christopher C: 5 articles (08/2015 - 01/2010)|
|7.||Engebretsen, Lars: 4 articles (08/2015 - 05/2008)|
|8.||Cole, Brian J: 4 articles (10/2012 - 06/2006)|
|9.||Rasmussen, Sten: 3 articles (10/2015 - 01/2012)|
|10.||Arendt-Nielsen, Lars: 3 articles (10/2015 - 01/2012)|
|1.||salicylhydroxamic acid (SHAM)IBA
01/01/2015 - "Non-invasive knee injury via tibial compression overload or sham injury was performed on a total of 90 mice. "
01/01/2015 - "Clinical outcome showed a significantly greater pain subscore on the Knee Injury and Osteoarthritis Outcome Score (KOOS) (indicative of improvement) with verum acupuncture than with sham acupuncture. "
01/01/2014 - "Clinical outcome showed a significantly greater Knee Injury and Osteoarthritis Outcome Score (KOOS) pain score (improvement) with verum acupuncture compared to the sham acupuncture. "
06/01/2010 - "Tissue-engineered cartilage constructs represent a highly promising treatment option for knee injury as they mimic the biomechanical environment of the native cartilage and have superior integration capabilities. "
03/01/2010 - "Medial shelf or "plica" syndrome is a pathological condition of the knee that often follows knee injury in young athletes, the symptoms of which often mimic other internal derangements of the knee. "
01/01/1985 - "Medial shelf or "plica" syndrome is a pathological condition of the knee that often follows knee injury in young athletes, the symptoms of which often mimic other internal derangements of the knee. "
|3.||Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
|4.||Morphine (MS Contin)FDA LinkGeneric
|5.||Calcitonin (Calcitonin, Eel)FDA LinkGeneric
|6.||arginine alpha-ketoisocaproate (AKIC)IBA
02/01/2015 - "The goal of this study is to present an audit of patients seen in a dedicated Acute Knee Injury Clinic (AKIC) to determine the frequency and appropriateness of MRI utilization. "
01/01/2012 - "The combined results from this study show that the C-AKIC is an appropriate, effective, and efficient model of clinical care for patients presenting with acute knee injuries."
01/01/2012 - "Overall, patients receiving care through the C-AKIC incurred 37% of the cost of patients with knee injuries in the comparison group and significantly incurred less costs when compared to the comparison group. "
01/01/2012 - "The goal of this paper is to evaluate and report on the appropriateness, efficiency, and effectiveness of the C-AKIC through healthcare utilization and costs associated with acute knee injuries. "
01/01/2012 - "Therefore, a new inter-disciplinary team-based model of care for managing acute knee injuries was developed in Calgary, Alberta, Canada: the Calgary Acute Knee Injury Clinic (C-AKIC). "
02/01/2014 - "Matched samples of SF, serum, plasma, and urine were obtained from 36 subjects at different time points after knee injury, and analysed for ARGS-aggrecan content. "
03/01/2011 - "Joint fluids from human patients after knee injury showed significantly enhanced levels of ARG-aggrecan compared to uninjured reference subjects. "
12/01/1994 - "The increased concentrations of aggrecan and COMP fragments and stromelysin-1 in the joint fluid of the contralateral, uninjured knee following unilateral knee injury, compared with concentrations in healthy reference knees, suggest changes in joint cartilage metabolism in both knees following unilateral knee injury. "
12/01/2012 - "The pattern and abundance of aggrecan fragments in synovial fluid (SF) aspirates from JIA patients were analyzed and compared with aggrecan fragments in SF from patients with other arthritides, children with knee injury, and a knee-healthy reference group. "
03/01/1999 - "Changes in joint cartilage aggrecan after knee injury and in osteoarthritis."
07/01/2005 - "In short, our data suggest that autologous chondrocyte-seeded type I/III collagen membrane is an effective method for the treatment of focal osteochondral knee injury in rabbits."
07/01/2014 - "In a rabbit model of knee injury, intra-articular injection of HA decreased adhesion formation and collagen content and increased ROM after prolonged immobilization. "
09/01/1998 - "Because of estrogen's direct effect on collagen metabolism and behavior and because neuromuscular performance varies during the menstrual cycle, it is logical to question the menstrual cycle's effect on knee injury rates. "
10/01/1996 - "The increased levels of pCol II-C in SF may reflect an increased rate of synthesis of collagen II in the joint cartilage of patients with knee injury and developing OA. "
10/01/1996 - "To determine in a cross sectional study the concentrations in joint fluid of the C-propeptide of collagen II (pCol II-C) in patients with knee injury and developing osteoarthritis (OA). "
|9.||Interleukin-1 (Interleukin 1)IBA
06/01/2010 - "Meniscal tears are a common knee injury and increased levels of interleukin-1 (IL-1) have been measured in injured and degenerated joints. "
12/01/2011 - "We propose a phase II, randomized, placebo-controlled, double-blinded, clinical trial to treat acute knee injuries with intraarticular injection of an IL-1 inhibitor. "
01/01/2010 - "We collected serum from 11 patients without pre-existing osteoarthritis from a pilot intervention trial (5 placebo and 6 drug treated) using an intra-articular interleukin-1 receptor antagonist (IL-1Ra) therapy, 9 of which also supplied matched synovial fluid samples at presentation to the clinic after acute knee injury (mean 15.2 ± 7.2 days) and at the follow-up visit for reconstructive surgery (mean 47.6 ± 12.4 days). "
01/01/2014 - "Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis."
|10.||Hyaluronic Acid (Hyaluronan)IBA
12/01/2009 - "This study evaluates the effectiveness of hyaluronic acid on cartilage healing after acute knee injury in sheep. "
07/01/2014 - "Intra-articular injection of hyaluronic acid for the reduction in joint adhesion formation in a rabbit model of knee injury."
05/01/2011 - "Intra-articular hyaluronic acid: potential treatment of younger patients with knee injury and/or post-traumatic arthritis."
03/01/2012 - "We asked whether (1) PRP immersed in a cell-free PGA-hyaluronan scaffold improves patient-reported 1-year outcomes for the Knee injury and Osteoarthritis Score (KOOS), and (2) implantation of the scaffold in combination with bone marrow stimulation leads to the formation of hyaline-like cartilage repair tissue. "
|1.||Activities of Daily Living (ADL)
07/18/2014 - "To understand the mechanical consequences of knee injury requires a detailed analysis of the effect of that injury on joint contact mechanics during activities of daily living. "
03/01/2011 - "For the past two decades arthroscopic surgery has revolutionized the treatment of acute traumatic knee injuries with patients returning sooner to activities of daily living. "
06/06/2012 - "The scores on the Short Form-36 (SF-36), Knee Injury and Osteoarthritis Outcome Score (KOOS) activities of daily living (ADL) scale, and International Knee Documentation Committee (IKDC) form improved from baseline (p < 0.05) to two years postoperatively in both treatment groups. "
08/01/2012 - "Health status was measured by three questionnaires: Knee injury and Osteoarthritis Outcome Score (KOOS); Knee Outcome Survey - Activities of Daily Living Scale (KOS-ADLS); and Medical Outcomes Study - 36 item Short Form (SF-36). "
06/01/2015 - "All patients were assessed with the SF-36 Physical Functioning and the Knee injury and Osteoarthritis Outcome Score ADL scores. "
09/01/1991 - "We conclude that the number of knee injuries is high among Swedish ice hockey players, and that the efficacy of functional knee braces to reduce knee injuries is questionable."
05/01/1990 - "The efficacy of a prophylactic knee brace to reduce knee injuries in football. "
03/01/1987 - "These facts lead us to question the efficacy of prophylactic knee braces in preventing knee injuries in college football. "
12/01/2007 - "There has been an increasing use of orthotic knee braces in the management of knee injuries but, to our knowledge, there is no gait analysis study assessing the accuracy of these braces. "
07/01/2000 - "This information will help athletes and coaches decide about knee-brace use during sports; studies are needed regarding whether braces protect against knee injury. "
05/01/2008 - "Static varus and external rotatory stability will be significantly improved in a knee with a grade 3 posterolateral knee injury after a proximal tibial medial opening wedge osteotomy. "
05/01/2008 - "The improved stability observed in some patients with grade 3 posterolateral knee injuries after a proximal tibial medial opening wedge osteotomy appears to at least in part be due to tightening of the superficial medial collateral ligament. "
01/01/2012 - "The 95% osteotomy survival rate in this study is in accordance with the results reported by Coventry et al. and Sprenger et al. With strict adherence to the indication criteria, we did not find any clear relationship between the severity of knee injury before surgery and the subjective evaluation of post-operative clinical outcome. "
05/01/2008 - "Increased stability of posterolateral corner knee injuries has been observed clinically after proximal tibial medial opening wedge osteotomies. "
11/01/2007 - "Patients with low-velocity knee injuries and isolated chronic posterolateral knee injuries may not require a second-stage soft tissue ligament reconstruction after healing the osteotomy and undergoing a program of rehabilitation."
05/01/2012 - "Increased knee flexion angles after resistance training may indicate a reduced risk for knee injury from improved neuromuscular control, resulting in a softer landing."
09/01/2015 - "Men older than age 45, with a history of knee injury or elevated body mass index (BMI), were randomized to low-load resistance training (30% 1RM) either with or without concurrent BFR. "
12/01/2007 - "The FWE appears to be as effective as standard resistance training equipment for improving knee extensor muscle group size and performance after knee injury."
12/01/2007 - "Comparison of conventional resistance training and the fly-wheel ergometer for training the quadriceps muscle group in patients with unilateral knee injury."
09/01/2015 - "However, factors that confer elevated risk of knee OA (eg, sedentary lifestyle, obesity, and knee injury) also contribute to a reduced tolerance of resistance training programs at ≥60% 1-repetition maximum (1RM). "
|5.||Homologous Transplantation (Allograft)
01/01/1999 - "Allografts are particularly helpful in these complex and time consuming knee injuries. "
10/01/2014 - "Combined anterior cruciate ligament and posterolateral reconstruction of the knee using allograft tissue in chronic knee injuries."
12/01/2012 - "Herein, we report the case of a young male who received arthroscopic lateral and medial meniscectomy and ACL tibialis allograft reconstruction performed with the double-tunnel and double-bundle technique approximately 8 months after a knee injury. "