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Kininogens (Kininogen)

Endogenous peptides present in most body fluids. Certain enzymes convert them to active KININS which are involved in inflammation, blood clotting, complement reactions, etc. Kininogens belong to the cystatin superfamily. They are cysteine proteinase inhibitors. HIGH-MOLECULAR-WEIGHT KININOGEN; (HMWK); is split by plasma kallikrein to produce BRADYKININ. LOW-MOLECULAR-WEIGHT KININOGEN; (LMWK); is split by tissue kallikrein to produce KALLIDIN.
Also Known As:
Kininogen; Prekinins; Prokinins; T-Kininogen; Thiostatin; Kininogen Cystatins; T Kininogen; Cystatins, Kininogen
Networked: 453 relevant articles (3 outcomes, 35 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Colman, Robert W: 8 articles (01/2018 - 07/2002)
2. Bhoola, Kanti D: 6 articles (01/2020 - 04/2004)
3. Isordia-Salas, Irma: 6 articles (06/2007 - 07/2002)
4. Revenko, Alexey S: 5 articles (01/2022 - 01/2018)
5. Figueroa, Carlos D: 5 articles (01/2020 - 07/2003)
6. McCrae, Keith R: 5 articles (01/2019 - 02/2008)
7. Kozik, Andrzej: 5 articles (01/2013 - 05/2005)
8. Pixley, Robin A: 5 articles (07/2006 - 07/2002)
9. Pesquero, João B: 4 articles (01/2019 - 11/2006)
10. Wang, Mengjun: 4 articles (11/2018 - 06/2009)

Related Diseases

1. Pre-Eclampsia (Preeclampsia)
2. Myocardial Infarction
3. Pancreatitis
4. Hyperlipidemias (Hyperlipidemia)
5. Inflammation (Inflammations)

Related Drugs and Biologics

1. Kinins
2. Kallikreins (Kallikrein)
3. Bradykinin
4. Tissue Kallikreins (Tissue Kallikrein)
5. Prekallikrein
6. Proteins (Proteins, Gene)
7. Carrageenan
8. Plasma Kallikrein
9. Factor XII (Hageman Factor)
10. Peptide Hydrolases (Proteases)

Related Therapies and Procedures

1. Cholecystectomy
2. Nephrectomy
3. Intravenous Administration
4. Therapeutics
5. Intravenous Injections