Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, oligopeptide-|-Xaa-Yaa, when Xaa is not Pro, and Yaa is neither Asp nor Glu. Thus, conversion of ANGIOTENSIN I to ANGIOTENSIN II, with increase in vasoconstrictor activity, but no action on angiotensin II. It is also able to inactivate BRADYKININ, a potent vasodilator; and has a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. (From https://www.uniprot.org April 15, 2020).
Also Known As:
Angiotensin Converting Enzyme; Angiotensin I-Converting Enzyme; Carboxycathepsin; Dipeptidyl Peptidase A; Kininase A; ACE1 Angiotensin Converting Enzyme 1; Angiotensin I Converting Enzyme; Carboxypeptidase I, Dipeptidyl; Peptidyl Dipeptidase A; ACE1 Angiotensin-Converting Enzyme 1; ACE1 Protein; Angiotensin Converting Enzyme 1; Antigens, CD143; CD143 Antigens; Dipeptidyl Carboxypeptidase I; Kininase II; Peptidase P
Networked: 10362
relevant articles (469 outcomes,
1689 trials/studies)
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Bio-Agent Context: Research Results
Experts
1. | Remuzzi, Giuseppe:
24 articles
(10/2019 - 12/2001)
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2. | Yusuf, Salim:
23 articles
(01/2019 - 01/2002)
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3. | Pfeffer, Marc A:
23 articles
(04/2016 - 08/2003)
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4. | Bernstein, Kenneth E:
22 articles
(01/2022 - 09/2004)
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5. | Solomon, Scott D:
21 articles
(01/2022 - 11/2003)
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6. | McMurray, John J V:
18 articles
(01/2022 - 09/2003)
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7. | Sturrock, Edward D:
17 articles
(01/2022 - 01/2003)
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8. | Danilov, Sergei M:
17 articles
(01/2021 - 12/2003)
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9. | Ruggenenti, Piero:
17 articles
(01/2019 - 12/2001)
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10. | Zhou, Tian-Biao:
17 articles
(06/2018 - 01/2011)
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