|1.||Seyfried, Thomas N: 9 articles (01/2015 - 08/2003)|
|2.||Sotgia, Federica: 7 articles (04/2014 - 04/2012)|
|3.||Lisanti, Michael P: 7 articles (04/2014 - 04/2012)|
|4.||Mukherjee, Purna: 6 articles (01/2015 - 10/2005)|
|5.||Martinez-Outschoorn, Ubaldo E: 6 articles (04/2014 - 04/2012)|
|6.||Whitaker-Menezes, Diana: 6 articles (05/2013 - 04/2012)|
|7.||Howell, Anthony: 5 articles (03/2013 - 04/2012)|
|8.||Veech, Richard L: 4 articles (10/2014 - 03/2004)|
|9.||Crawford, Peter A: 4 articles (07/2013 - 01/2011)|
|10.||Ala-Korpela, Mika: 3 articles (07/2015 - 10/2013)|
01/01/1994 - "The present study shows that the human brain adapts to the changes in energy supply as early as 3 days following initiation of starvation, at which time ketone bodies account for approximately one-fourth of the cerebral energy requirements."
01/01/2015 - "The metabolism of ketone bodies is an alternative energy source for the brain under conditions of starvation. "
11/01/2013 - "Ketone bodies are usually present in the blood, and their level increases during fasting and starvation. "
02/15/2013 - "Together, these data suggest that, at the tissue level, ketone bodies are not a required energy substrate in the newborn period or during starvation, but rather that integrated ketone body metabolism mediates adaptation to ketogenic nutrient states."
02/15/2013 - "Here, we use novel transgenic and tissue-specific SCOT-KO mice to demonstrate that ketone bodies do not serve an obligate energetic role within highly ketolytic tissues during the ketogenic neonatal period or during starvation in the adult. "
05/01/2011 - "These preliminary results suggest that seizures associated with HH may respond favorably to the KD, and that ketone bodies might directly modulate the intrinsic epileptogenicity of HH tissue. "
12/01/2014 - "Previous studies have shown that the mechanisms underlying seizure control involve ketone bodies, which are produced by fatty acid oxidation. "
08/27/2015 - "Because of problems with compliance to this diet, there is an interest in evaluating alternative pharmacological treatments that can have anti-seizure effects by elevating ketone bodies. "
05/01/2010 - "Yet, a direct role for ketone bodies in limiting seizure and neuronal damage remains poorly understood. "
11/01/2008 - "The major measures used to evaluate dietary effectiveness have been the levels of urinary ketone bodies and the successful reduction of seizure activity. "
03/01/2012 - "In some instances, such as in refractory epilepsy, high levels of ketone bodies can be beneficial-in this instance, by exerting an anticonvulsant effect. "
06/28/2011 - "It also showed that ketone bodies are effective in controlling epilepsy. "
04/01/2012 - "Ketone bodies in epilepsy."
01/01/2010 - "From the bench to the bedside: Breaking down the blood-brain barrier, decoding the habenula, understanding hand choice, and the role of ketone bodies in epilepsy."
09/01/2003 - "Because of the safety record of ketone bodies in the treatment of epilepsy and their ability to penetrate the blood-brain barrier, DbetaHB may be a novel neuroprotective therapy for PD."
03/01/2001 - "The objective of this study was to investigate the relationship between the concentrations of the different ketone bodies in milk and blood and to evaluate these concentrations for the detection of subclinical ketosis. "
02/01/1987 - "The study indicates that the hepatic release of ketone bodies might be auto-limited by ketoacidosis."
05/01/1986 - "This study examines the effects of a 2-h exercise of moderate intensity (50% of VO2 max) on the tracer-determined turnover rate of ketone bodies (KB) in 21 normal subjects fasted for 16 h, 5 days, whose basal ketonemia ranged between 0.09 and 6.16 mM. The KB response observed at the end of exercise is a function of the initial degree of ketosis. "
01/01/1924 - "Studies on Ketosis: II. The Oxidation of Ketone Bodies by the Isolated Liver of the Rat."
09/01/2015 - "Alcoholic ketoacidosis is a medical emergency, which is characterized at first by an elevated level of ketone bodies. "
10/01/2014 - "Previous studies indicate that unlike healthy tissues, cancer cells are unable to effectively use ketone bodies for energy. "
01/01/2009 - "The goal of the current study was to test the hypothesis that ketone bodies can inhibit cell growth in aggressive cancers and that expression of uncoupling protein 2 is a contributing factor. "
01/01/2014 - "We observed reduced glycolytic flux in tumor cells upon treatment with ketone bodies. "
01/01/2014 - "The levels of ketone bodies in cancer tissues with differentiated histology and in intestinal-type cancer tissues were significantly increased. "
11/01/2012 - "We have previously proposed that catabolic fibroblasts generate mitochondrial fuels (such as ketone bodies) to promote the anabolic growth of human cancer cells and their metastasic dissemination. "
|3.||3-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)
|4.||Adenosine Triphosphate (ATP)
|5.||Nonesterified Fatty Acids (NEFA)
|6.||Blood Glucose (Blood Sugar)
|2.||Transjugular Intrahepatic Portasystemic Shunt
|3.||Carbohydrate-Restricted Diet (Low Carbohydrate Diet)