Darier Disease (Darier's Disease)
An autosomal dominantly inherited skin disorder characterized by warty malodorous papules that coalesce into plaques. It is caused by mutations in the ATP2A2 gene encoding SERCA2 protein, one of the SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. The condition is similar, clinically and histologically, to BENIGN FAMILIAL PEMPHIGUS, another autosomal dominant skin disorder. Both diseases have defective calcium pumps (CALCIUM-TRANSPORTING ATPASES) and unstable desmosomal adhesion junctions (DESMOSOMES) between KERATINOCYTES.
Also Known As:
Darier's Disease; Acantholytic Dyskeratotic Epidermal Nevi; Acantholytic Dyskeratotic Epidermal Nevus; Acrokeratosis Verruciformis; Hopf Disease; Darier White Disease; Darier-White Diseases; Dariers Disease; Disease, Darier; Disease, Darier's; Disease, Darier-White; Disease, Hopf; Diseases, Darier-White; Diseases, Hopf; Hopf Acrokeratosis Verruciformis; Hopf Diseases; Verruciformis, Acrokeratosis; Acrokeratosis Verruciformis of Hopf; Darier-White Disease; Keratosis Follicularis
Networked: 229
relevant articles (21 outcomes,
25 trials/studies)
for this Disease,
Comments
Relationship Network
Disease Context: Research Results
Related Diseases
Experts
| 1. | Hovnanian, Alain: 6 articles (10/2006 - 09/2003) |
| 2. | Shimizu, H: 4 articles (04/2004 - 04/2000) |
| 3. | Hovnanian, A: 3 articles (05/2004 - 12/2000) |
| 4. | Leslie, Natalie: 3 articles (12/2003 - 09/2003) |
| 5. | Dhitavat, Jittima: 3 articles (12/2003 - 09/2003) |
| 6. | Takahashi, H: 2 articles (03/2007 - 07/2003) |
| 7. | Szigeti, Réka: 2 articles (11/2006 - 01/2006) |
| 8. | Kellermayer, Richard: 2 articles (11/2006 - 01/2006) |
| 9. | Yamasaki, Kazuo: 2 articles (08/2006 - 08/2004) |
| 10. | Takahashi, Hidetoshi: 2 articles (08/2006 - 08/2004) |
Drugs and Biologics
Drugs and Important Biological Agents (IBA) related to Darier Disease:Therapies and Procedures
TREATMENT OPTIONS
for Darier Disease,
Ranking and Evidence
for Darier Disease,
Ranking and Evidence
*WARNING* This specific disease subtype has a relatively small
number of significant evidence outcomes. You may proceed to order anyway, or go back to the search field and enter a
more general type of the target illness. Once your report has been ordered, however, we can't refund the purchase.
CureHunter Patient-Physician Summary Reports collect in one document all the
medications ever reported in the US National Library of Medicine—1949 to the present—to
be effective against your target disease.
Analytic charts allow you and your physicians to see at a glance the
treatment options—including new, promising, off-label and experimental.
- Free Updates for 1 Year
- All 21 Outcomes
- Top 109 Key Drugs and Biologics
- Top 17 Key Therapies and Procedures
- Detailed History Charts
- Full Research Evidence References
- Sample PDF Report on Psoriasis >>
| Price: | $8.50 USD
& Delivery via
PDF download
updates for 1 year |
Research Interface PRO
- Two-clicks from Disease to Drug to Evidence: Drill down to full abstract
- Enable Experts: Quickly identify key researchers and their publications
- Enable FDA Link Generic: Two-clicks to FDA Products/Patents/Generics
- Enable Export: All outcome statements and scores exportable to Excel/TSV for automated meta-analysis
- Research Network: Explore drug and disease relationships visually
- Enable Mobile Interface: Access from your cellphone, iPhone or PDA
| Price: | $45.00 USD
access via web interface 1 year subscription |