|2.||Basal Cell Carcinoma (Rodent Ulcer)
|5.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
|1.||Cohen, Philip R: 4 articles (09/2014 - 11/2005)|
|2.||Robert, Caroline: 4 articles (04/2014 - 08/2009)|
|3.||Batinac, Tanja: 4 articles (03/2013 - 01/2006)|
|4.||Dummer, Reinhard: 3 articles (03/2014 - 04/2011)|
|5.||Li, Tao: 3 articles (02/2014 - 12/2003)|
|6.||Hadzisejdic, Ita: 3 articles (11/2006 - 01/2006)|
|7.||Zamolo, Gordana: 3 articles (11/2006 - 01/2006)|
|8.||Li, Xinmin: 2 articles (06/2015 - 03/2013)|
|9.||Forslund, Ola: 2 articles (06/2015 - 08/2003)|
|10.||Ra, Seong H: 2 articles (06/2015 - 03/2013)|
|1.||Methotrexate (Mexate)FDA LinkGeneric
12/01/1991 - "We report an open, noncontrolled study of nine consecutive patients with unusually large or strategically located solitary keratoacanthomas treated successfully with intralesional methotrexate. "
06/01/1995 - "Two such cases of large keratoacanthoma of the nose were treated successfully with intralesional methotrexate. "
05/01/2012 - "Intralesional methotrexate (IL-MTX) is an effective treatment for keratoacanthoma. "
06/01/2007 - "Intralesional methotrexate (MTX) is an effective treatment for keratoacanthoma (KA). "
02/19/1994 - "[Effective treatment of recurrent keratoacanthoma using methotrexate]."
|2.||Fluorouracil (Carac)FDA LinkGeneric
11/01/2014 - "To determine the efficacy of treating patients with a recent onset, biopsy-proven keratoacanthoma with short-contact topical 5% 5-fluorouracil cream twice daily until resolution. "
12/01/1991 - "Intralesional therapy, particularly with 5-fluorouracil, has been shown to be effective in the treatment of keratoacanthomas. "
05/01/1986 - "Intralesional 5-fluorouracil (5-FU) has been shown to be an effective treatment for keratoacanthoma. "
11/01/2014 - "Clinical efficacy of short contact topical 5-Fluorouracil in the treatment of keratoacanthomas: a retrospective analysis."
11/01/2014 - "The authors performed a retrospective analysis of 10 patients with biopsy-confirmed keratoacanthomas treated with topical 5-fluorouracil. "
11/01/1990 - "Thus oral retinoids are only partially beneficial for the treatment of the Grzybowski type or the Witten and Zak type of multiple eruptive keratoacanthomas."
02/01/2014 - "Clearance of BRAF inhibitor-associated keratoacanthomas by systemic retinoids."
04/01/2002 - "The efficacy of retinoids, previously reported in the treatment of solitary giant keratoacanthoma, multiple keratoacanthoma and keratoacanthoma centrifugum marginatum, was demonstrated even in this handicapping form of keratoacanthoma."
08/16/2013 - "Systemic retinoids for recurrent keratoacanthomas."
11/01/1990 - "Two patients with multiple keratoacanthomas were treated with oral retinoids. "
|4.||Isotretinoin (Accutane)FDA LinkGeneric
08/01/1994 - "Oral isotretinoin (Accutane, Roche Laboratories) has been reported to be an effective treatment of multiple as well as solitary keratoacanthomas. "
11/01/2008 - "The authors report of a man with multiple eruptive keratoacanthomas of Grzybowski who responded favorably to oral isotretinoin therapy. "
11/01/2008 - "Generalized eruptive keratoacanthomas of Grzybowski treated with isotretinoin."
08/01/1994 - "A 45-year-old man with a large keratoacanthoma on the nasal ala, recurrent after surgical excision, was treated with 1 mg/kg/day (80 mg/day) oral isotretinoin (Accutane). "
08/01/1994 - "Treatment of a recurrent keratoacanthoma with oral isotretinoin."
|5.||Tretinoin (Retinoic Acid)FDA LinkGeneric
01/01/2014 - "Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk."
07/01/2011 - "Treatment of keratoacanthoma centrifugum marginatum with topical tretinoin."
10/01/1970 - "The uptake of labeled vitamin A acid in keratoacanthoma. "
08/01/1967 - "The effect of vitamin A acid on hyperkeratinization and the keratoacanthoma."
08/01/1971 - "Modification of the effect of vitamin A acid on the skin tumor keratoacanthoma by applications of actinomcin D."
02/01/2015 - "Acitretin induces remission in generalized eruptive keratoacanthoma of Grzybowski."
07/01/2010 - "The authors report a patient who developed multiple, eruptive keratoacanthomas in the red ink portions of a tattoo and was successfully treated with acitretin."
11/01/2006 - "Multiple palmar keratoacanthomas treated with acitretin."
11/01/2007 - "A case of Ferguson-Smith type multiple keratoacanthomas associated with keratoacanthoma centrifugum marginatum: response to oral acitretin."
08/01/2014 - "Regression of B-RAF inhibitor associated keratoacanthomas by acitretin - how do retinoids act on the RAF/MEK/ERK-signaling pathway?"
|7.||Cyclosporine (Ciclosporin)FDA LinkGeneric
07/07/1990 - "[Multiple keratoacanthoma during cyclosporin therapy]."
11/01/2004 - "We report two patients with explosive basal cell carcinoma and keratoacanthoma development, respectively, within 3 months of initiation of cyclosporine. "
11/01/2004 - "Early and explosive development of nodular basal cell carcinoma and multiple keratoacanthomas in psoriasis patients treated with cyclosporine."
09/01/2013 - "Four patients had an associated eczematous dermatitis and were also treated with cyclosporine with improvement in pruritus and prurigo nodules and no increase in keratoacanthomas. "
07/01/2014 - "Multiple reactive keratoacanthomas in a patient with hypertrophic lichen planus treated with cyclosporine: successful treatment with acitretin."
03/01/2012 - "There is also anecdotal evidence suggesting the efficacy of PDT for the treatment of keratoacanthomas (KA). "
09/01/2006 - "We present a case of a patient developing a keratoacanthoma immediately following PDT for AKs."
08/01/2003 - "PDD and PDT were used for diagnostics and treatment of different dermatoses (basal cell carcinomas, malignant melanoma metastases, verrucae vulgares, keratoacanthomas, solitary lesions of T lymphoma--mycosis fungoides, m. "
|9.||Cyclophosphamide (Cytoxan)FDA LinkGeneric
|1.||Photochemotherapy (Photodynamic Therapy)
03/01/2012 - "Efficacy of topical photodynamic therapy for keratoacanthomas: a case-series of four patients."
11/01/1999 - "Efficacy of topical photodynamic therapy of a giant keratoacanthoma demonstrated by partial irradiation."
12/01/2015 - "Commentary on Eruptive Keratoacanthomas After Photodynamic Therapy."
12/01/2015 - "Eruptive Keratoacanthomas After Photodynamic Therapy."
08/01/2010 - "Keratoacanthoma aggravated after photodynamic therapy."
|2.||Mohs Surgery (Mohs' Micrographic Surgery)
02/01/2012 - "Mohs micrographic surgery appears to be an effective option in the management of this unusual variant of keratoacanthoma, which is often difficult to eradicate."
02/01/2012 - "Recurrent distal digital keratoacanthoma of the periungual region treated with Mohs micrographic surgery."
08/01/2009 - "Mohs micrographic surgery is a logical treatment option for giant keratoacanthomas. "
08/01/2009 - "Giant keratoacanthoma of the upper extremity treated with mohs micrographic surgery: a case report and review of current treatment modalities."
09/01/2007 - "Mohs micrographic surgery for an unusual case of keratoacanthoma arising from a longstanding tattoo."
12/01/2004 - "The objective was to evaluate the efficacy of Er:YAG laser surgery combined with topical 5-fluorouracil treatment in a case of recurrent giant keratoacanthoma. "
12/01/2004 - "Combined 5-fluorouracil and Er:YAG laser treatment in a case of recurrent giant keratoacanthoma of the lower leg."
12/01/2004 - "The combined use of ablative Er:YAG laser and topical 5-fluorouracil chemotherapy may be considered as an effective treatment option in cases of giant keratoacanthoma when conventional surgery is not indicated."
01/01/2014 - "Imiquimod as neoadjuvant treatment for giant keratoacanthoma arising on a background of lupus vulgaris."
10/01/2011 - "[Intralesional infusion of methotrexate as neoadjuvant therapy improves the cosmetic and functional results of surgery to treat keratoacanthoma: results of a randomized trial]."