|1.||Thomé, Jean-Pierre: 4 articles (06/2015 - 03/2013)|
|2.||Multigner, Luc: 4 articles (07/2014 - 07/2010)|
|3.||Cordier, Sylvaine: 4 articles (07/2014 - 07/2010)|
|4.||Monfort, Christine: 3 articles (07/2014 - 03/2013)|
|5.||Rouget, Florence: 3 articles (07/2014 - 03/2013)|
|6.||Kadhel, Philippe: 3 articles (07/2014 - 03/2013)|
|7.||Sobel, Eric S: 3 articles (09/2007 - 03/2005)|
|8.||Roberts, Stephen M: 3 articles (09/2007 - 03/2005)|
|9.||Costet, Nathalie: 2 articles (07/2014 - 03/2014)|
|10.||Wang, Fei: 2 articles (09/2007 - 02/2006)|
01/01/1986 - "Most such studies, however, have used relatively high doses of chlordecone so it has been difficult to determine if the serotoninergic change preceded or resulted from the tremor. "
01/01/1985 - "Drugs with known pharmacological effects were used to study the possible mechanism of chlordecone-induced tremor. "
01/01/1985 - "Studies on the mechanism of chlordecone-induced tremor in rats."
09/30/1983 - "Studies on the possible sites of chlordecone-induced tremor in rats."
08/01/1991 - "The reduced sexual behavior after chlordecone treatment preceded the onset of marked chlordecone-induced tremor. "
08/01/2008 - "[Chlordecone and cancer in French-West Indies]."
06/01/1989 - "In contrast, none of comparably treated males had malignant liver tumors, even after 44 weeks of 'promotion' with chlordecone. "
06/01/1989 - "Although the toxicity of chlordecone in women has never been studied, we found a dramatic sex difference in the incidence of malignant liver tumors caused by chlordecone promotion in rats. "
06/01/1989 - "Chlordecone acted largely as a liver tumor promoter rather than as a complete hepatic carcinogen in both male and female Sprague-Dawley rats. "
01/01/1987 - "Isolated adrenal cortical cells of a mouse tumor line (Y-1), when incubated in media containing 10(-5) M chlordecone, responded with increased ODC activity. "
|3.||Body Weight (Weight, Body)
01/01/1992 - "In addition, chlordecone treatment inhibited food intake within 2 hr. Consequently, these results suggest that chlordecone suppresses food intake which in turn produces the decline in body weight."
01/01/1992 - "The effects of the chlorinated pesticide chlordecone on food intake, body weight, and water intake were examined in adult male rats. "
01/01/1992 - "Effects of chlordecone on food intake and body weight in the male rat."
01/01/1991 - "Chlordecone also rapidly suppressed food intake and led to a significant decline in body weight; these nutritional factors could have contributed to the disrupted estrous cycle. "
01/01/1990 - "The extent of liver toxicity in rats fed 10 ppm chlordecone (CD) for 15 days prior to the injection of a single low dose of BrCCl3 (15 microL/kg body weight) or after exposure to a high dose of BrCCl3 (80 microL/kg body weight) without CD pretreatment, was similar 6 and 24 hr later as assessed by plasma transaminase levels. "
11/01/1993 - "The present studies were designed to evaluate whether hepatic failure is the cause of the lethality during chlordecone-amplified CCl4 toxicity. "
08/01/1993 - "Exposure to very low levels of chlordecone results in highly exaggerated toxicity of ordinarily nontoxic doses of halomethane because of suppressed hepatocellular regeneration and restoration, permitting the progression of liver injury ultimately resulting in liver failure and animal mortality. "
11/01/1993 - "Hepatic failure leads to lethality of chlordecone-amplified hepatotoxicity of carbon tetrachloride."
|5.||Breast Neoplasms (Breast Cancer)
03/01/2014 - "Activity of the sinusoidal influx transporter OCT1 (organic cation transporter 1) was thus inhibited by endosulfan, chlordane, heptachlor, lindane, and dieldrine, but not by dichlorodiphenyltrichloroethane isomers, whereas those of the canalicular efflux pumps MRP2 (multidrug resistance-associated protein 2) and BCRP (breast cancer resistance protein) were blocked by endosulfan, chlordane, heptachlor, and chlordecone; this latter OC additionally inhibited the multidrug resistance gene 1 (MDR1)/P-glycoprotein (P-gp) activity. "
05/01/2008 - "This study investigated the effects of E2, diethylstilbestrol (DES), antiestrogens, the phytoestrogen resveratrol, and the xenoestrogens octylphenol (OP), nonylphenol (NP), endosulfan, kepone, 2,3,4,5-tetrachlorobiphenyl-4-ol (HO-PCB-Cl(4)), bisphenol-A (BPA), and 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) on induction of luciferase activity in breast cancer cells transfected with a construct (pSp1(3)) containing three tandem GC-rich Sp binding sites linked to luciferase and wild-type or variant ERalpha. "
|1.||Muscarinic Receptors (Muscarinic Acetylcholine Receptor)
|2.||Acetylcholine (Acetylcholine Chloride)
|5.||Serotonin (5 Hydroxytryptamine)
|7.||Estrogen Receptor Modulators (Antiestrogen)
|8.||Neurotransmitter Agents (Neurotransmitter)