Isoproterenol (Isoprenaline)

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4222 relevant articles (161 outcomes, 405 trials/studies) found for this Drug

Description: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.

Also Known As:

Isoprenaline; Isuprel; Norisodrine; 4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol; Euspiran; Isadrin; Isadrine; Isopropyl Noradrenaline; Isopropylnoradrenaline; Isopropylnorepinephrine; Isoproterenol Hydrochloride; Isoproterenol Sulfate; Izadrin; Novodrin; Hydrochloride, Isoproterenol; Noradrenaline, Isopropyl; Sulfate, Isoproterenol; Isopropylarterenol; 1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-

Relationship Network

Drug Context: Research Results

Organic Chemicals: 42

dichloroisoproterenol: 13

clorprenaline: 5

hydroxybenzylisoproterenol: 5

1-phenyl-2-isopropylaminoethanol

2-(3,4-diacetoxyphenyl)-2-chloro-N-isopropyl-1-ethanamine

3-O,4-O-diacetylisoproterenol

3-O,4-O-dibenzoylisoproterenol

4-chloroisoprenaline

di-4-toluoylisoproterenol

dipivaloylisoproterenol

isolevin

metiprenaline

Experts

1.	Anandan, R: 4 articles (03/2007 - 09/2004)
2.	Rajadurai, M: 4 articles (01/2007 - 02/2005)
3.	Stanely Mainzen Prince, P: 4 articles (01/2007 - 01/2006)
4.	Devi, C S Shyamala: 4 articles (08/2006 - 03/2002)
5.	Sangeetha, T: 3 articles (07/2008 - 01/2006)
6.	Sankar, T V: 3 articles (03/2007 - 09/2004)
7.	Kumar, S Hari Senthil: 3 articles (01/2006 - 09/2004)
8.	Shiny, K S: 3 articles (01/2006 - 09/2004)
9.	Sood, S: 3 articles (11/2005 - 12/2003)
10.	Maulik, S K: 3 articles (11/2005 - 12/2003)

Related Diseases

1.	Tachycardia (Tachyarrhythmias) 01/01/2003 - "In vivo studies indicated significantly improved therapeutic efficacy of MT from Ms with sustained and controlled inhibition of isoprenaline-induced tachycardia as compared with oral and nasal administration of drug solution." 10/01/1984 - "Drugs effective against induction of isoproterenol-facilitated ventricular tachyarrhythmias were identified in 13 of 25 trials. " 02/01/1991 - "An isoproterenol challenge appears to be helpful in predicting late recurrence of tachycardia." 10/01/2009 - "Comparative pharmacokinetic-pharmacodynamic studies with four beta blockers were performed in conscious rats, using heart rate under isoprenaline-induced tachycardia as a pharmacodynamic endpoint. " 12/01/2005 - "METHODS: The study population consists of nine children, age range 6-13 years (median 9) with previously documented SVT who had no tachyarrhythmia inducible during EP study (at baseline and following isoprenaline infusion). " Order ALL the reference details at left...
2.	Necrosis 03/01/1974 - "Biochemical changes of myocardial necrosis induced by isoproterenol and protective effects of beta-blocker and anti-inflammatory drugs." 06/25/2007 - "This study appraised the efficacy of OA and UA in protecting the heart against oxidative damage induced by isoproterenol, since oxidative injury has been investigated as a potential initiator of myocardial necrosis. " 01/01/1998 - "Role of Lipistat in protection against isoproterenol induced myocardial necrosis in rats: a biochemical and histopathological study." 06/01/2009 - "This study investigates the cardioprotective activity of a combined treatment of Ginkgo biloba phytosomes (GBP) and Ocimum sanctum extract (Os) in isoproterenol (ISO)-induced myocardial necrosis in rats. " 03/01/1998 - "CONCLUSIONS: This study demonstrates that isoproterenol-induced myocardial necrosis resulted in progressive hemodynamic dysfunction of the left ventricle which most closely correlated with alterations in LV geometry. " Order ALL the reference details at left...
3.	Asthma (Bronchial Asthma) 09/01/1984 - "There was no significant difference in the unstimulated cAMP levels before exercise in the three groups, but stimulation with isoprenaline caused a significantly greater rise in cAMP in the non-atopic, non-asthmatic subjects when compared to both the atopic asthmatics and the atopic subjects without asthma. " 04/01/1975 - "Notable acute improvement in pulmonary function in the majority of 32 patients with known bronchial asthma followed two inhalations of Isoproterenol. " 06/01/2004 - "Despite the controversy of bronchial responsiveness to beta2-agonist drugs in asthma, in a previous study we have shown increased responsiveness of asthmatic tracheobronchial tree to isoprenaline. " 12/01/2003 - "Despite the controversy of airway responsiveness to beta2-agonist drugs in asthma, in a previous study we showed increased responsiveness of asthmatic airways to isoprenaline. " 05/01/1977 - "Using this as an in vitro cell model to study beta-adrenergic response, granulocyte reaction to isoproterenol was examined in asthma. " Order ALL the reference details at left...
4.	Myocardial Infarction 02/01/2009 - "The present study evaluated cardioprotective effect of lyophilized hydroalcoholic extract of Moringa oleifera in the isoproterenol (ISP)-induced model of myocardial infarction. " 12/01/2008 - "Thus, our study shows that SAC has a protective role in isoproterenol-induced myocardial infarction in rats. " 09/01/2008 - "The results of our study showed the cardioprotective potential of Marutham on isoproterenol induced myocardial infarction in rats." 05/01/2008 - "Thus, this study confirmed the preventive effect of EGCG on isoproterenol-induced mitochondrial damage in experimentally induced myocardial infarction in Wistar rats." 01/01/2008 - "In the present study, cardioprotective effect of aqueous extract of fruits of Embelia ribes Burm (ER) was evaluated in a rat model having acute myocardial infarction, induced by isoproterenol (5.25 and 8.5 mg/kg, sc, for two consecutive days). " Order ALL the reference details at left...
5.	Heart Failure 08/01/2006 - "However, during heart failure, long-term NCX overexpression over 2 wk significantly improved fractional shortening and dP/dt(max) compared with AdGFP-infected rabbits, both without inotropic stimulation and after beta-adrenergic stimulation with isoproterenol. " 06/01/1992 - "Isoproterenol is therefore effective in controlling myocardial failure during acute rejection despite a reduced sensitivity of the sinoatrial node and myocardial tissue." 04/01/2009 - "OBJECTIVE: To explore the effects of transplanted BMSCs (bone marrow mesenchymal stem cells) on cardiac function and ventricular remodeling in rats with isoproterenol (ISO) induced heart failure. " 04/01/2009 - "In vivo, global heart failure was induced in Wistar rats by isoproterenol (ISO) injection. " 02/01/2009 - "In 4-week but not in 2-week models, the increase from baseline in baseline developed tension produced by beta-adrenergic stimulation (isoproterenol, 10(-8) and 10(-7) mol/L) was significantly increased in heart failure-partial unloading compared with heart failure-complete unloading and heart failure (P < .05). " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Epinephrine (Adrenaline)
2.	Norepinephrine (Noradrenaline)
3.	Propranolol (Inderal)
4.	Isoproterenol (Isoprenaline)
5.	Atropine (Hyoscyamine)
6.	Adenylate Cyclase (Adenylyl Cyclase)
7.	Aminophylline (Carine)
8.	Adrenergic Receptors (Adrenergic Receptor)
9.	Calcium
10.	Histamine (Histamine Dihydrochloride)

Related Therapies and Procedures

1.	Intravenous Infusions
2.	Respiratory Therapy (Therapy, Respiratory)
3.	Injections
4.	Oral Administration
5.	Nebulizers and Vaporizers (Inhaler)

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