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Isoniazid (Ftivazide)

4857  relevant articles (182 outcomes, 381 trials/studies) found for this Drug

Description: Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.

Also Known As:
Ftivazide; Isonicotinic Acid Hydrazide; Isonex; Phthivazide; Tubazide; Hydrazide, Isonicotinic Acid; 4-Pyridinecarboxylic acid, hydrazide

Relationship Network

Drug Context: Research Results

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Experts

1. Vernon, Andrew: 4 articles (05/2005 - 06/2002)
2. Khuller, G K: 4 articles (09/2003 - 02/2001)
3. Chaisson, Richard E: 3 articles (07/2007 - 06/2005)
4. Yoshiyama, Takashi: 3 articles (02/2007 - 11/2006)
5. Ito, Kunihiko: 3 articles (02/2007 - 11/2006)
6. Peloquin, Charles A: 3 articles (12/2006 - 05/2003)
7. Burman, William: 3 articles (05/2005 - 08/2002)
8. Tuberculosis Trials Consortium: 3 articles (05/2005 - 08/2002)
9. Benator, Debra: 3 articles (05/2005 - 08/2002)
10. Khan, Awal: 3 articles (05/2005 - 08/2002)

Related Diseases

1. Tuberculosis
2. Pulmonary Tuberculosis
04/01/1996 - "OBJECTIVES: To compare the pharmacokinetic parameters and the clinical efficacy of isoniazid, administered in 10 mg/kg or 5 mg/kg to children suffering from pulmonary tuberculosis. "
11/15/2004 - "In these studies, the EBA of isoniazid during the first 2 days of treatment was determined for 97 patients with sputum smear-positive pulmonary tuberculosis following isoniazid doses of < or =37.5 mg, 75 mg, 150 mg, 300 mg, and 600 mg. The NAT2 genotype was determined in 70 patients, and the association between EBA and genotype was examined in this subgroup. "
01/01/2003 - "A complex approach to the therapy of patients with destructive pulmonary tuberculosis is suggested, within the study, with regard for the presence of multidrug-resistance of Mycobacterium tuberculosis (MBT), for a degree of inactivation of isoniazid and for a degree of bacterial-static activity of patient's blood, which provides for a higher treatment efficiency."
09/01/2001 - "In light of the study findings, and as per the recommendation of the World Health Organization, we suggest that a 4-drug regimen, as an initial treatment for pulmonary tuberculosis should be maintained, as resistance to isoniazid is still higher than the cut off value of 4%, and susceptibility testing for first line antituberculosis drugs should be carried out whenever possible. "
02/01/1977 - "1. The acetylator phenotype of over 600 pulmonary tuberculosis patients treated with intermittent isoniazid-containing regimens in two controlled clinical trials was determined using either sulphadimidine or a slow-release isoniazid formulation. "
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3. Infection
4. Seizures (Seizure)
5. Meningeal Tuberculosis (Tuberculous Meningitis)

Related Drugs and Biologics

1. Rifampin (Rifampicin)
2. Pyrazinamide
3. Streptomycin (Streptomycin Sulfate)
4. Ethambutol (Myambutol)
5. Tuberculin (PPD)
6. p-Aminosalicylic Acid (PAS)
7. Ofloxacin (Levofloxacin)
8. Rifabutin (Ansamycin)
9. Thioacetazone (Thiacetazone)
10. Pyridoxine (Pyridoxin)

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Chemoprevention
3. Retreatment
4. Aftercare (After-Treatment)
5. Transplantation (Transplant Recipients)

Best Treatments:
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