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Isatin

An indole-dione that is obtained by oxidation of indigo blue. It is a MONOAMINE OXIDASE INHIBITOR and high levels have been found in urine of PARKINSONISM patients.
Also Known As:
2,3-Dioxoindoline; 2,3 Dioxoindoline; 1H-Indole-2,3-dione
Networked: 72 relevant articles (6 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Hou, Lin: 4 articles (11/2014 - 03/2008)
2. Hamaue, N: 4 articles (01/2006 - 04/2000)
3. Song, Jinlian: 3 articles (11/2014 - 07/2008)
4. Yue, Wang: 3 articles (02/2013 - 03/2008)
5. Ogata, A: 3 articles (01/2006 - 07/2000)
6. Minami, M: 3 articles (01/2006 - 07/2000)
7. Tashiro, K: 3 articles (01/2006 - 07/2000)
8. Sriram, Dharmarajan: 3 articles (05/2005 - 11/2004)
9. Bal, Tanushree Ratan: 3 articles (05/2005 - 11/2004)
10. Yogeeswari, Perumal: 3 articles (05/2005 - 11/2004)

Related Diseases

1. Acquired Immunodeficiency Syndrome (AIDS)
05/01/2005 - "In this paper, we designed aminopyrimidinimino isatin lead compound as a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) with broad-spectrum chemotherapeutic properties for the effective treatment of AIDS and AIDS-related OIs. "
01/01/2005 - "In this paper, we describe an aminopyrimidinimino isatin lead compound as a novel non-nucleoside reverse transcriptase inhibitor with broad-spectrum chemotherapeutic properties for the effective treatment of AIDS and AIDS-related opportunistic infections. "
05/01/2005 - "Newer aminopyrimidinimino isatin analogues as non-nucleoside HIV-1 reverse transcriptase inhibitors for HIV and other opportunistic infections of AIDS: design, synthesis and biological evaluation."
05/01/2005 - "HIV is the most significant risk factor for many opportunistic infections like tuberculosis, bacterial infections etc. In this paper, we designed aminopyrimidinimino isatin lead compound as a novel non-nucleoside reverse transcriptase inhibitor with broad-spectrum chemotherapeutic properties for the effective treatment of AIDS and AIDS-related opportunistic infections. "
11/15/2004 - "HIV is the most significant risk factor for many opportunistic infections like tuberculosis, hepatitis, bacterial infections, etc. In this paper, we designed aminopyrimidinimino isatin lead compound as a novel non-nucleoside reverse transcriptase inhibitor with broad-spectrum chemotherapeutic properties for the effective treatment of AIDS and AIDS-related opportunistic infections. "
2. AIDS-Related Opportunistic Infections
3. Opportunistic Infections (Opportunistic Infection)
4. Tuberculosis (Tuberculoses)
5. Bacterial Infections (Bacterial Infection)

Related Drugs and Biologics

1. RNA-Directed DNA Polymerase (Reverse Transcriptase)
2. Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)
3. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
4. Pentylenetetrazole (Metrazol)
5. Chitosan
6. Urea (Carbamide)
7. Quinazolines
8. Mannich Bases
9. Hydrazones
10. Monoamine Oxidase (MAO)

Related Therapies and Procedures

1. Intraperitoneal Injections
2. Drug Therapy (Chemotherapy)
3. Skin Transplantation (Skin Grafting)
4. Therapeutics