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Intestinal Perforation

Opening or penetration through the wall of the INTESTINES.
Also Known As:
Intestinal Perforations; Perforation, Intestinal; Perforations, Intestinal
Networked: 457 relevant articles (10 outcomes, 13 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Peritonitis
2. Sepsis (Septicemia)
3. Inflammation
4. Septic Shock (Toxic Shock Syndrome)
5. Lymphoma (Lymphomas)

Experts

1. Ehrenkranz, R A: 5 articles (01/2008 - 01/2001)
2. Attridge, J T: 4 articles (05/2009 - 02/2006)
3. Gordon, P V: 4 articles (08/2008 - 02/2006)
4. Halliday, H L: 4 articles (01/2003 - 01/2001)
5. Matsui, Hiroki: 3 articles (12/2015 - 01/2015)
6. Tagami, Takashi: 3 articles (12/2015 - 01/2015)
7. Fushimi, Kiyohide: 3 articles (12/2015 - 01/2015)
8. Yasunaga, Hideo: 3 articles (12/2015 - 01/2015)
9. Walsh, Michele C: 3 articles (11/2014 - 07/2012)
10. Stoll, Barbara J: 3 articles (11/2014 - 04/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Intestinal Perforation:
1. Indomethacin (Indometacin)FDA LinkGeneric
2. Azathioprine (Imuran)FDA LinkGeneric
3. Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
4. Dacarbazine (DIC)FDA LinkGeneric
5. ThrombomodulinIBA
6. Phenobarbital (Luminal)FDA Link
7. Anesthetics (Anesthetic Agents)IBA
8. 5- (benzoylamino)- N- (4- chlorophenyl)- 3- methyl- 4- isothiazolecarboxamide (ITCL)IBA
9. ROPIBA
01/01/2001 - "Data regarding clinical outcomes including mortality, failure to extubate, pulmonary air leak, survival without chronic lung disease, CLD defined at 28 days postnatal age and 36 weeks post menstrual age, patent ductus arteriosus (PDA), severe intraventricular haemorrhage (IVH), periventricular leucomalacia (PVL), infection, hyperglycaemia, hypertension, severe retinopathy of prematurity (ROP), necrotising enterocolitis (NEC), gastrointestinal bleeding, intestinal perforation and long-term outcomes were abstracted and analysed using RevMan 4.1. "
01/01/2008 - "None of the trials reported on outcomes such as requirement for retreatment with indomethacin or surgical ligation, mortality, bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), neurodevelopmental outcome and isolated intestinal perforation. "
01/01/2008 - "There were no statistically significant differences in mortality, reopening of the ductus, need for surgical duct ligation, duration of ventilator support, duration of supplementary oxygen, pulmonary hemorrhage, pulmonary hypertension, CLD, IVH, PVL, NEC, intestinal perforation, gastrointestinal bleed, time to full enteral feeds, time to regain birth weight, ROP, sepsis, duration of hospitalization. "
01/01/2001 - "Data regarding clinical outcomes including mortality before discharge, failure to extubate, infection, hyperglycaemia, hypertension, severe retinopathy of prematurity (ROP), necrotizing enterocolitis (NEC), gastrointestinal bleeding, intestinal perforation, echodensities on ultrasound scan of brain, need for home oxygen, glycosuria, need for late rescue with dexamethasone, cerebral palsy in survivors and blindness in survivors including a study reporting 5 year follow-up were abstracted and analysed using Revman 4.1. "
01/01/2003 - "Data regarding clinical outcomes including mortality, CLD (including need for home oxygen, or need for late rescue with corticosteroids), death or CLD, failure to extubate, complications in the primary hospitalisation (including infection, hyperglycaemia, glycosuria, hypertension, echodensities on ultrasound scan of brain, necrotising enterocolitis (NEC), gastrointestinal bleeding, intestinal perforation, and severe retinopathy of prematurity (ROP)), and long term outcome (including blindness, deafness, cerebral palsy and major neurosensory disability), were abstracted and analysed using RevMan 4.1. "
10. Dexamethasone (Maxidex)FDA LinkGeneric

Therapies and Procedures

1. Laparotomy
2. Enteral Nutrition (Feeding, Tube)
3. Ileostomy
4. Gastrostomy
5. Colectomy