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Interleukin-1 (Interleukin 1)

A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
Also Known As:
Interleukin 1; Lymphocyte Activating Factor; IL-1; Epidermal Cell Derived Thymocyte-Activating Factor; Interleukin I; Macrophage Cell Factor; T Helper Factor; Epidermal Cell Derived Thymocyte Activating Factor; Lymphocyte-Activating Factor
Networked: 10822 relevant articles (390 outcomes, 1162 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Dinarello, Charles A: 81 articles (01/2022 - 01/2002)
2. Iwakura, Yoichiro: 54 articles (01/2019 - 02/2002)
3. Abbate, Antonio: 46 articles (11/2022 - 04/2009)
4. Rothwell, Nancy J: 36 articles (01/2018 - 05/2002)
5. Allan, Stuart M: 30 articles (01/2020 - 10/2003)
6. Joosten, Leo A B: 29 articles (01/2022 - 06/2003)
7. Pinteaux, Emmanuel: 29 articles (07/2021 - 05/2002)
8. Van Tassell, Benjamin W: 28 articles (11/2022 - 02/2010)
9. Apte, Ron N: 27 articles (01/2018 - 08/2002)
10. Goldbach-Mansky, Raphaela: 26 articles (01/2022 - 12/2002)

Related Diseases

1. Inflammation (Inflammations)
2. Neoplasms (Cancer)
3. Infections
4. Rheumatoid Arthritis
5. Necrosis

Related Drugs and Biologics

1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
2. Interleukin-6 (Interleukin 6)
3. Cytokines
4. Interleukin 1 Receptor Antagonist Protein (Anakinra)
5. Interleukin-1 Receptors (Interleukin 1 Receptor)
6. Proteins (Proteins, Gene)
7. Interleukins
8. Interleukin-10 (Interleukin 10)
9. Colchicine
10. Inflammasomes

Related Therapies and Procedures

1. Therapeutics
2. Injections
3. Biological Therapy
4. Immunotherapy
5. Transplantation