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Interleukin-1 (Interleukin 1)

A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
Also Known As:
Interleukin 1; Lymphocyte Activating Factor; IL-1; Epidermal Cell Derived Thymocyte-Activating Factor; Interleukin I; Macrophage Cell Factor; T Helper Factor; Epidermal Cell Derived Thymocyte Activating Factor; Lymphocyte-Activating Factor
Networked: 9454 relevant articles (309 outcomes, 1050 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Iwakura, Yoichiro: 63 articles (12/2015 - 02/2002)
2. Dinarello, Charles A: 51 articles (12/2015 - 01/2002)
3. Rothwell, Nancy J: 37 articles (12/2015 - 05/2002)
4. Apte, Ron N: 23 articles (05/2014 - 08/2002)
5. Joosten, Leo A B: 21 articles (01/2015 - 06/2003)
6. Voronov, Elena: 21 articles (04/2014 - 08/2002)
7. Allan, Stuart M: 20 articles (12/2015 - 10/2003)
8. Abbate, Antonio: 20 articles (02/2015 - 10/2002)
9. Goldbach-Mansky, Raphaela: 18 articles (12/2015 - 12/2002)
10. Gabay, Cem: 18 articles (01/2015 - 02/2002)

Related Diseases

1. Inflammation
2. Rheumatoid Arthritis
3. Infection
4. Neoplasms (Cancer)
5. Arthritis (Polyarthritis)

Related Drugs and Biologics

1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
2. Interleukin 1 Receptor Antagonist Protein (Anakinra)
3. Interleukin-6 (Interleukin 6)
4. Cytokines
5. Interleukin-10 (Interleukin 10)
6. Interleukin-1beta (Interleukin 1 beta)
7. Interleukin-1 (Interleukin 1)
8. Interleukins
9. Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
10. Interleukin-1alpha (Interleukin 1 alpha)

Related Therapies and Procedures

1. Injections
2. Transplantation (Transplant Recipients)
3. Drug Therapy (Chemotherapy)
4. Intra-Articular Injections
5. Transplants (Transplant)