Immune System Diseases (Immune Disorders)

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1222 relevant articles (47 outcomes, 85 trials/studies) found for this Disease

Description: Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both.

Also Known As:

Immune Disorders; Immune Disease; Immune Disorder; Immune Diseases; Disease, Immune; Disorders, Immune; Diseases of Immune System; Immunological Diseases; Disease, Immune System; Disease, Immunologic; Disease, Immunological; Diseases, Immune; Diseases, Immune System; Diseases, Immunologic; Diseases, Immunological; Disorder, Immune; Immune System Disease; Immunologic Disease; Immunological Disease; Immunologic Diseases

Relationship Network

Disease Context: Research Results

Immune System Diseases: 1222

Hypersensitivity: 35690

Autoimmune Diseases: 11434

Graft vs Host Disease: 7915

Thrombocytopenic Purpura: 1452

Membranoproliferative Glomerulonephritis: 795

Immune Reconstitution Inflammatory Syndrome: 153

Blood Group Incompatibility: 101

Immunologic Deficiency Syndromes: 67

Immunoproliferative Disorders: 26

Related Diseases

1.	Arthritis (Polyarthritis)
2.	Rheumatoid Arthritis
3.	Inflammation
4.	Systemic Lupus Erythematosus (Libman-Sacks Disease)
5.	Encephalomyelitis (Myeloencephalitis)
276 Diseases and 519 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Immune System Diseases:

1.	AntibodiesIBA 04/01/2006 - "When the biological sample contains heterophilic antibodies (such as in patients with auto-immune diseases), these non-specific antibodies can cause false positive results" 01/01/2003 - "The involvement of CCR1 in immunological diseases now is documented in several preclinical studies with CCR1 deficient mice, anti-CCR1 antibodies and CCR1 antagonists, suggesting that CCR1 may be an attractive therapeutic target for a variety of diseases" 01/01/2008 - "Autoimmune haemolytic anaemia (AIHA) is an immune disorder caused by antibodies directed against unmodified autologous red cells" 10/01/2006 - "Pathogenesis moved more towards an immune disorder, to the production of (auto)antibodies against a component of the lipolytic system" 03/01/2006 - "Auto-antibodies directed against CaSRs, seen in auto-immune diseases, can lead to similar clinical presentations" Get all the results and reference details, order at left...
2.	AutoantibodiesIBA 05/01/1999 - "In contrast, 6 of 53 patients without concurrent immune diseases and no or low-titer autoantibodies had treatment-related remission" 05/01/1999 - "MATERIAL AND METHODS: Patients were selected for study if they had been screened for autoantibodies and concurrent immune diseases and if viral genotyping had been performed or was possible" 05/01/2006 - "Some of these autoantibodies are thought to be closely related to the auto-immune disease whereas for some others their pathogenesis role is still unclear" 06/01/2003 - "2. Demonstration of autoantibodies on wide-scale palette helps to state the diagnosis based on the systematic auto-immune disease connection" 02/01/2002 - "This could interfere with the production of autoantibodies in some immune diseases" Get all the results and reference details, order at left...
3.	Immunoglobulin G (IgG)IBA 01/01/2006 - "The majority of these deficiencies are subtle IgG subclass deficits, whereas more severe humoral immune disorders are a rare finding" 01/01/1999 - "A common variable immune disease was diagnosed in three patients that was characterized by an additional defect in the IgG main class" 01/01/1994 - "High-dosage intravenous human immunoglobulin G (i.v. IgG) has been used with varying degrees of success to treat a variety of auto-immune disorders which are frequently characterized by a predominantly pathogenic auto-antibody" 11/01/1993 - "Additionally, these patients had higher serum immunoglobulin G levels (3300 +/- 216 mg/dL vs. 2732 +/- 192 mg/dL, P = 0.05) and a greater frequency of concurrent immunologic diseases (59% vs. 27%, P = 0.005)" 06/01/1984 - "The most pertinent factors to be considered are i) the heterogeneity of an immune disease investigated; ii) the criteria used to evaluate the effects of the IgG therapy; iii) the IgG preparations used and i.v. dose-fractionation" Get all the results and reference details, order at left...
4.	Immunoglobulins (Immunoglobulin)IBA 09/04/1993 - "Human polyvalent immunoglobulins administered intravenously have shown to be effective in some immune diseases" 06/01/2006 - "BACKGROUND: Intravenous immunoglobulin (IGIV) is used in the treatment of a wide variety of immune disorders" 06/01/2000 - "Laboratory findings were abnormal (immunoglobulins and lymphocyte populations), suggesting an immune disorder" 01/01/1995 - "The examinees with euthyroid condition had immune disorders with an allergic tendency (increased number of B-lymphocytes, immunoglobulins A)" 03/01/1990 - "Serum immunoglobulins from patients with polyclonal immune disorder also showed molecular sized heterogeneity" Get all the results and reference details, order at left...
5.	rituximab (Mabthera)FDA Link 07/01/2005 - "The monoclonal antibody anti-CD20 (rituximab), able to suppress the tumoral cells and change the B-cell repertoire is the most promising treatment to cure immune disorders related to NHL" 08/01/2008 - "Rituximab off-label use for immune diseases: assessing adverse events in a single-centre drug-utilization survey." 02/01/2008 - "Rituximab is increasingly used off label for difficult-to-treat auto-immune diseases" 02/01/2008 - "Rituximab off label use for difficult-to-treat auto-immune diseases: reappraisal of benefits and risks." 08/01/2006 - "Rituximab use in severe auto-immune diseases has recently increased" Get all the results and reference details, order at left...
6.	Interleukin-2 (IL2)IBA 04/01/1997 - "Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor." 06/01/1993 - "This principle can be widely used with those immunological diseases where IL-2 level is decreased through downregulation" 01/01/1990 - "The possible application of PA to the treatment of immune disorders involving deficiency of IL-2 production and/or IL-2 responsiveness of lymphocytes is also considered." 10/01/2001 - "Zinc is essential for human health, and its deficiency in human beings results in growth failure, immune disorders affecting Th1 functions, decreased interleukin-2 (IL-2) production, and cognitive impairment" 09/01/1998 - "To understand the clinical efficacy of traditional anti-rheumatic herbal medicines on acute and severe arthritis or immune diseases, four herbal formulas and one herb were tested in vitro to determine their effects on prostaglandin E2 (PGE2) and interleukin 2 (IL2)" Get all the results and reference details, order at left...
7.	triptolideIBA 01/01/2005 - "Triptolide has been reported to be effective in the treatment of auto-immune diseases" 05/31/2001 - "Triptolide, a traditional Chinese medicine, has been reported to be effective in the treatment of auto-immune diseases, and it can also induce anti-neoplastic activity on several human tumor cell lines" Get all the results and reference details, order at left...
8.	AntigensIBA 09/01/1990 - "Because clinical studies indicate that these antigens are involved in mediating corneal graft rejection and possibly in glaucomatous disease of the eye, the presence of both class I and II HLA in the corneal endothelium and in the trabecular cells has important implications for an understanding of immune disorders in the anterior segment of the eye" 08/01/2008 - "The former is thought not only to function as a mechanism to exclude B cell clones possessing the ability to react with self-antigen, but also to participate as a defense mechanism from auto-immune diseases" 02/01/2007 - "Comprehensive profiling of the humoral and cellular immune responses, including molecular composition, the specificity of the response, the cellular activation, differentiation, and homing status, will aid to improve diagnosis, classification, monitoring, and prognostication of immune disorders driven by antigen-specific B- and T-lymphocytes." 10/01/2005 - "We discuss the skin environment as a privileged anatomical site for therapeutic intervention against pro-inflammatory auto-immune disorders using non-invasive approaches for antigen delivery." 09/01/2003 - "Antigen-specific CD4+ T cells and antigen-presenting dendritic cells (DCs) are important mediators in the pathogenesis of auto-immune disease and thus are ideal candidates for adoptive cellular gene therapy, an ex vivo approach to therapeutic gene transfer" Get all the results and reference details, order at left...
9.	Complement System Proteins (Complement)IBA 07/01/1995 - "We argue that an appreciation of the role of local complement synthesis may help to explain many features of organ- and tissue-specific immunological disease." 12/01/2003 - "Investigation of complement is useful for diagnosis and following of auto-immune diseases" 01/01/1995 - "The involvement of complement in other immunological diseases is an expanding area of clinical research, supported by the development of new assays for the identification of complement activation" 10/01/1990 - "Inherited complement deficiency is rare, but the perspective is widened by the more common occurence of acquired defects in immunological diseases, and the apparent requirement for efficient complement recruitment in host defense" 10/01/1990 - "Inherited complement deficiency states: implications for immunity and immunological disease." Get all the results and reference details, order at left...
10.	InterferonsIBA 02/01/2000 - "It has been clearly demonstrated that interferon may induce or worsen such immunological diseases, but there are very few studies showing improvement of these manifestations under interferon" 01/01/1999 - "Interferon may induce or worsen these immunologic diseases, but there are very few studies showing improvement of these manifestations with interferon." 07/01/1983 - "Further studies on the immunoregulatory effects of the different types of interferons are also necessary to elucidate whether interferon is involved in the pathophysiology of immune disorders." 09/01/2007 - "Side effects of interferon include possible triggering or exacerbation of immune diseases in consequence of immunomodulatory effects" 03/01/2001 - "Interferon (IFN) alpha, a cytokine capable of promoting IFN-gamma synthesis, has been implicated in the development of Th1 mediated immune diseases" Get all the results and reference details, order at left...
554 Drugs and Important Bio-Agents and 1101 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Organ Transplantation 05/01/2002 - "Because this side effect of MMF may also occur after solid organ transplantation and in other immune disorders, pharmacokinetic profiling of MPA and MPA acyl glucuronide is needed in future studies with MMF." 02/01/2005 - "This review discusses the advances in researches on the mechanism of MSCs' immunoregulatory function and potential clinical application in immune disease and organ transplantation." 04/01/2003 - "While its application clearly is efficacious in the inhibition of T-cell proliferation and results in the decrease of inflammatory processes, its side effects in long-term use manifested most prominently through nephrotoxicity have been the main concern against broader use of the drug in inflammatory and immune diseases other than organ transplantation" 03/01/1993 - "An important challenge in the field of auto-immune diseases, bone marrow and organ transplantation is the control of T-lymphocyte activation" 09/29/2005 - "Haematopoietic stem cell transplantation (HSCT) offers promise for the treatment of haematological and immune disorders, solid tumours, and as a tolerance inducing regimen for organ transplantation" Get all the results and reference details, order at left...
2.	Stem Cell Transplantation 03/01/2006 - "The Accreditation Subcommittee of the EBMT regularly publishes special reports on current practice of haemopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders in Europe" 04/01/2002 - "The Accreditation Sub-Committee of the EBMT regularly publishes special reports on current practice of haemopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders" 09/29/2005 - "Haematopoietic stem cell transplantation (HSCT) offers promise for the treatment of haematological and immune disorders, solid tumours, and as a tolerance inducing regimen for organ transplantation" 03/01/2004 - "Recently stem cell transplantation has been suggested like novel treatment in some severe auto-immune diseases, specifically in severe and refractory to conventional treatment in systemic lupus erythematosus patients" Get all the results and reference details, order at left...
3.	Plasma Exchange 07/01/1983 - "Plasma exchange in hemato-immunologic diseases--studies of 205 cases]" 01/01/1992 - "Plasma exchange therapy of maternofetal immune disease]" 01/01/1990 - "Plasma exchange in immunological disease." 07/01/1985 - "11 patients with auto immune diseases and dermatological diseases underwent 230 consecutive plasma exchanges" 04/26/1984 - "So far we have treated 48 patients with 206 plasma exchanges, most ot them because of immune diseases such as systemic lupus erythematodes and immunvascultits ." Get all the results and reference details, order at left...
4.	Drug Therapy (Chemotherapy) 03/01/2008 - "Consequently, we must appreciate the functioning of these molecules as we strive to discover and optimize new GPCR drug therapies for endocrine, metabolic and immune disorders." 12/01/2005 - "Many drug therapies have been developed that aim to alleviate or prevent such immune disorders and restore immune homeostasis" 01/01/2004 - "Besides, it was noted that there were intensifying signs of immune disorders primarily observed during irradiation chemotherapy" 12/01/1991 - "Pharmacotherapy of immune diseases]" 12/01/1981 - "The procedure might thus be extended to a wider number of immunological diseases where drug therapy fails to take effect." Get all the results and reference details, order at left...
5.	Thymectomy 10/01/1987 - "This case emphasizes that thymectomy frequently has little effect on the course of the immunologic disease" 01/01/1986 - "Certain immunological diseases are a relative indication for thymectomy" 01/01/1985 - "Effect of thymectomy in immune diseases other than myasthenia." 02/04/1984 - "Benefit of thymectomy in immune diseases other than myasthenia." 01/01/1985 - "In the course of thymectomy of patients with myasthenia gravis, surprising data concerning the recovery or considerable improvement of other immune disorders have been observed" Get all the results and reference details, order at left...
50 Therapies and Procedures and 185 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Patient-Physician Research Summary Report on Immune System Diseases

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