Immunoglobulin Fc Fragments

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
Also Known As:
Immunoglobulin Fc Fragment; Immunoglobulins, Fc; Immunoglobulins, Fc Fragment; Fc Fragment Immunoglobulins; Fc Fragment, Immunoglobulin; Fc Fragments, Immunoglobulin; Fragment Immunoglobulins, Fc; Fc Fragments; Fc Immunoglobulins
Networked: 51 relevant articles (4 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Lünemann, Jan D: 1 article (11/2015)
2. Münz, Christian: 1 article (11/2015)
3. Giddens, John P: 1 article (11/2015)
4. Tackenberg, Björn: 1 article (11/2015)
5. Quast, Isaak: 1 article (11/2015)
6. Dalakas, Marinos C: 1 article (11/2015)
7. Keller, Christian W: 1 article (11/2015)
8. Wang, Lai-Xi: 1 article (11/2015)
9. Maurer, Michael A: 1 article (11/2015)
10. Nimmerjahn, Falk: 1 article (11/2015)

Related Diseases

1. Autoimmune Diseases (Autoimmune Disease)
2. Infection
3. Thrombocytopenic Purpura (Thrombopenic Purpura)
4. Polyneuropathies (Polyneuropathy)
5. Neuritis (Polyneuritis)

Related Drugs and Biologics

1. Immunoglobulin G (IgG)
2. Intravenous Immunoglobulins (IVIG)
3. Immunoglobulins (Immunoglobulin)
4. Monoclonal Antibodies
5. N-Acetylneuraminic Acid (Sialic Acid)
6. Antibodies
7. Immunoglobulin A (IgA)
8. Antigens
9. Proteins (Proteins, Gene)
10. Peptide Hydrolases (Proteases)