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Immunoglobulin Variable Region

That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.
Also Known As:
Framework Region, Immunoglobulin; Ig Framework Region; Ig Variable Region; Immunoglobulin Framework Region; Immunoglobulin V; Framework Region, Ig; Framework Regions, Ig; Framework Regions, Immunoglobulin; Ig Framework Regions; Ig Variable Regions; Immunoglobulin Framework Regions; Immunoglobulin Variable Regions; Regions, Immunoglobulin Variable; Variable Regions, Ig; Variable Regions, Immunoglobulin; Variable Region, Ig; Variable Region, Immunoglobulin
Networked: 137 relevant articles (1 outcomes, 11 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Stevenson, Freda K: 7 articles (10/2015 - 02/2002)
2. Stott, David I: 5 articles (02/2014 - 01/2005)
3. Rosenquist, Richard: 5 articles (07/2005 - 04/2003)
4. Mehr, Ramit: 4 articles (02/2014 - 04/2006)
5. Ottensmeier, Christian H: 4 articles (03/2008 - 04/2002)
6. Thunberg, Ulf: 4 articles (07/2005 - 04/2003)
7. Sundström, Christer: 4 articles (07/2005 - 04/2003)
8. Zuckerman, Neta S: 3 articles (02/2014 - 12/2006)
9. Chiorazzi, Nicholas: 3 articles (01/2013 - 09/2002)
10. Hamblin, Terry J: 3 articles (11/2011 - 02/2002)

Related Diseases

1. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
2. Lymphoma (Lymphomas)
3. Neoplasms (Cancer)
4. B-Cell Lymphoma (Lymphoma, B Cell)
5. Rheumatoid Arthritis

Related Drugs and Biologics

1. Epitopes
2. Myeloma Proteins
3. Antibodies
4. Immunoglobulins (Immunoglobulin)
5. Antigens
6. Immunoglobulin M (IgM)
7. Autoantibodies
8. DNA (Deoxyribonucleic Acid)
9. Vaccines
10. Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)

Related Therapies and Procedures

1. Immunotherapy