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Immunoglobulin Idiotypes (Idiotype, Immunoglobulin)

Unique, genetically controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
Also Known As:
Idiotype, Immunoglobulin; Immunoglobulin Idiotype; Idiotypes, Immunoglobulin
Networked: 49 relevant articles (5 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Timmerman, John M: 4 articles (03/2009 - 06/2003)
2. Hollander, Nurit: 4 articles (01/2009 - 03/2002)
3. Levy, Ronald: 3 articles (01/2011 - 12/2004)
4. Haimovich, Joseph: 3 articles (03/2008 - 03/2002)
5. Zirlik, Katja: 2 articles (09/2010 - 11/2006)
6. Heining-Mikesch, Kristina: 2 articles (09/2010 - 11/2006)
7. Veelken, Hendrik: 2 articles (09/2010 - 11/2006)
8. Weng, Wen-Kai: 2 articles (01/2009 - 12/2004)
9. Neelapu, Sattva S: 2 articles (06/2008 - 01/2007)
10. Dermime, Said: 2 articles (07/2004 - 05/2004)

Related Diseases

1. Lymphoma (Lymphomas)
2. Neoplasms (Cancer)
3. B-Cell Lymphoma (Lymphoma, B Cell)
4. Non-Hodgkin Lymphoma (Lymphosarcoma)
5. Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular)

Related Drugs and Biologics

1. Vaccines
2. Antigens
3. Antibodies
4. CD20 Antigens
5. Listeria monocytogenes hlyA protein (listeriolysin O)
6. Monoclonal Antibodies
7. Proteins (Proteins, Gene)
8. Peptides
9. Epitopes
10. keyhole-limpet hemocyanin (keyhole limpet hemocyanin)

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Immunotherapy
3. Subcutaneous Injections