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Immune Complex Diseases (Immune Complex Disease)

Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
Also Known As:
Immune Complex Disease; Disease, Immune Complex; Diseases, Immune Complex; Hypersensitivities, Type III; Type III Hypersensitivities; Hypersensitivity, Type III; Type III Hypersensitivity
Networked: 369 relevant articles (14 outcomes, 24 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Systemic Lupus Erythematosus (Libman-Sacks Disease)
2. Glomerulonephritis
3. Vasculitis (Vasculitides)
4. Infection
5. Inflammation

Experts

1. Kulkarni, Onkar P: 4 articles (11/2011 - 08/2007)
2. Anders, Hans-Joachim: 4 articles (11/2011 - 08/2007)
3. Lichtnekert, Julia: 3 articles (11/2011 - 08/2007)
4. Anolik, Jennifer H: 3 articles (02/2010 - 01/2006)
5. Fogo, Agnes B: 2 articles (07/2013 - 07/2003)
6. Novak, Jan: 2 articles (05/2013 - 05/2012)
7. Renfrow, Matthew B: 2 articles (05/2013 - 05/2012)
8. Julian, Bruce A: 2 articles (05/2013 - 05/2012)
9. Allam, Ramanjaneyulu: 2 articles (11/2011 - 01/2011)
10. Ryu, Mi: 2 articles (08/2011 - 01/2011)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Immune Complex Diseases:
1. Antigen-Antibody Complex (Immune Complex)IBA
2. Complement System Proteins (Complement)IBA
3. AntibodiesIBA
4. AntigensIBA
5. Monoclonal AntibodiesIBA
6. DNA (Deoxyribonucleic Acid)IBA
7. Immunoglobulin A (IgA)IBA
8. Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
9. Rheumatoid FactorIBA
10. nafamostatIBA

Therapies and Procedures

1. Enzyme Therapy
2. Plasmapheresis
3. Plasma Exchange
4. Immunomodulation
5. Transplants (Transplant)