Ileitis

01/01/2019 - "SAMP × Fn14-/- showed a marked decrease in ileitis severity at 20 weeks of age compared with SAMP WT controls. "
04/01/2015 - "Administration of R848 to adult SAMP mice increased migration of DC to the MLN and development of regulatory T cells there, and reduced the severity of ileitis. "
01/01/2018 - "In this study, we tested a specific DR3 agonistic antibody (4C12) in SAMP1/YitFc (SAMP) mice with CD-like ileitis. "
01/01/2012 - "The aim of this study was to determine the mechanism(s) of VSL#3-mediated protection on epithelial barrier function and to further investigate the "paradoxical" effects of TNF in preventing SAMP ileitis. "
01/01/2006 - "The aim of the present study was to develop a noninvasive imaging modality to detect and evaluate ileitis in SAMP1/YitFc (SAMP) mice. "

01/01/2017 - "Antibiotic treatment of B27-Tg rats markedly reduced the severity of ileitis, plasma levels of CCL2 and IL-1α, and number of BM and blood Lin-CD172a+CD43low monocytes, a cell subset shown in the present study to have the greatest in vitro osteoclastogenic potential. "
07/01/2007 - "Gnotobiotic mice, in which any cultivable gut bacteria were eradicated by antibiotic treatment, were used to study the role of LPS in ileitis. "
11/01/2002 - "The aim of this study was to determine the effects and elucidate the mechanisms of action of antibiotic treatment in the SAMP1/YitFc mouse model of ileitis. "
11/17/2023 - "Depletion of gut microbiota by broad-spectrum antibiotic treatment in Phb1∆PC or Phb1i∆IEC mice revealed a necessary role of microbiota to cause ileitis. "
10/01/2022 - "In the presence of significant prepouch ileitis or CD-like complications, chronic antibiotics and probiotics are inappropriate. "

10/27/2017 - "GP-1a attenuated murine ileitis, as demonstrated by improved histological scoring and decreased inflammatory cytokine expression. "
01/01/2023 - "All three kinds of PS-NPs triggered Crohn's ileitis-like features, such as ileum structure impairment, increased proinflammatory cytokines and intestinal epithelial cell (IEC) necroptosis, and PS-COOH/PS-NH2 NPs exhibited higher adverse effects on ileum tissues. "
07/15/2022 - "To measure ileitis severity inflammatory cytokines (IL-1β, TNFα, IL-6) levels were assessed. "
01/01/2020 - "The effect of SPL inhibition on circulating and tissue lymphocytes, transcriptional regulation of proinflammatory cytokines, and on the histological severity of ileitis was additionally examined. "
01/01/2019 - "TNF-driven ileitis was also prevented in TNFΔARE/+xDR3-/- mice, in association with decreased expression of the pro-inflammatory cytokines TNF and IFN-γ. "

01/01/2020 - "The efficacy of a novel inactivated intradermal Lawsonia intracellularis vaccine, Porcilis® Lawsonia ID, was evaluated in two experimental vaccination-challenge studies and under field conditions on a farm with a history of recurrent acute ileitis. "
01/01/2019 - "The efficacy of the new vaccine was further tested under field conditions on a farm with a history of acute ileitis. "
07/01/2013 - "This study was conducted to evaluate the efficacy of a commercial oral attenuated Lawsonia intracellularis vaccine (Enterisol Ileitis) against PPE under a commercial pig farm condition in Korea. "
01/01/2019 - "intracellularis, while Porcilis Ileitis (a vaccine) is the least cost-effective strategy. "
10/01/2012 - "Additionally, during fattening the control group displayed higher mortality (6,3 %) than the three vaccinated groups (Ingelvac(®) CircoFLEX(TM) 2,5 %, Enterisol(®) Ileitis 2,3 % and the combination of both vaccines 1,1 %). "

01/01/2018 - " stellen einen 32-jährigen Mann vor, der mit Infliximab, Prednisolon und Azathioprin aufgrund einer schweren Ileitis terminals Crohn behandelt wurde. "
07/06/2021 - "Infliximab is effective as maintenance therapy for recurrent chronic ulcerative ileitis in an isolated ITx patient."
07/06/2021 - "Maintenance treatment with infliximab for ulcerative ileitis after intestinal transplantation: A case report."
08/22/2008 - "The LIR!C-trial is a randomized multicenter trial that will provide evidence whether infliximab treatment or surgery is the best treatment for recurrent distal ileitis in Crohn's disease. "
08/22/2008 - "Laparoscopic ileocolic resection versus infliximab treatment of distal ileitis in Crohn's disease: a randomized multicenter trial (LIR!C-trial)."

04/01/2015 - "Budesonide is used as first-line treatment for a first episode of ileitis. "
10/01/2022 - "Ileal-release budesonide was rated appropriate in 6/16 scenarios including patients with significant prepouch ileitis but no CD-like complications. "
10/01/1995 - "Effects of plain and controlled-ileal-release budesonide formulations in experimental ileitis."
05/23/1998 - "Controlled ileal release budesonide (9 mg daily) induces clinical remission in 60-70% of patients with Crohn's ileitis or right-sided colitis, and continued budesonide treatment has a finite effect on the duration of remission. "
11/01/2007 - "Localized eosinophilic ileitis with mastocytosis successfully treated with oral budesonide."

07/01/2014 - "IL-17A was pathogenic, while IL-22 was protective against ileitis. "
06/01/2008 - "Bovine glycomacropeptide ameliorates experimental rat ileitis by mechanisms involving downregulation of interleukin 17."
10/01/2014 - "In contrast, ileal IL-23 expression, ER stress, lymph node IL-17A production, goblet cell loss, and ileitis development were microbiota-dependent. "
12/21/2009 - "Moreover, IL-23-dependent up-regulation of IL-22 was essential for the development of ileitis, whereas IL-17 was down-regulated and dispensable. "

01/01/2014 - "Pituitary adenylate cyclase-activating polypeptide ameliorates experimental acute ileitis and extra-intestinal sequelae."
01/01/2019 - "Our preclinical intervention study provides strong evidence that synthetic PACAP alleviates subacute ileitis and extra-intestinal including systemic sequelae of T cell-driven immunopathology. "
01/01/2019 - "Notably, ileitis-associated gut microbiota shifts were less distinct in PACAP as compared to placebo treated mice. "
01/01/2019 - "In our present preclinical intervention study we addressed whether PACAP treatment could alleviate experimental subacute ileitis mimicking human gut microbiota conditions. "
01/01/2014 - "So far, potential immune-modulatory properties of PACAP have not been investigated in experimental ileitis. "

09/01/2002 - "In this study, postcapillary submucosal collecting venules located at the junction of mesentery and ileum are introduced and evaluated for IVM in a rat model of indomethacin-induced ileitis. "
01/01/1999 - "The objective of this study was to assess the effect of Gln on leukocyte-endothelial cell interaction in an indomethacin (Indo)-induced long-lasting ileitis in Sprague-Dawley rats. "
05/01/2008 - "During the early stages of indomethacin-induced ileitis, epithelial barrier damage and abnormal bacterial infiltration into the mucosa occurred in conjunction with initial redistribution of CD103+DC. "
08/01/2006 - "Indomethacin-induced acute ileitis led to repression of ASBT in wild-type mice and in the transgenic rat ASBT promoter reporter, while paradoxical activation of ASBT was seen in c-fos-null mice. "
04/01/2005 - "Indomethacin-induced ileitis is associated with tensiometric, vascular and oxidative changes in the experimental rat model."

07/08/2003 - "TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis."
09/01/2010 - "Feeding studies in tumor necrosis factor (TNF)Delta ARE/+ mice, a mouse model for experimental ileitis, revealed that neither VSL#3 nor L. "
12/14/2021 - "Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor."
11/01/2011 - "We studied the roles of RA in mice that overproduce tumor necrosis factor (TNF) and develop chronic ileitis (TNF_ARE mice). "
02/15/2005 - "These L-selectin+ T cells were the main producers of TNF-alpha and the predominant ileitis-inducing subpopulation. "

12/01/2013 - "Magnetic resonance-enteroclysis (MRE) offers excellent imaging of transmural and peri-enteric lesions in Crohn's ileitis and we aimed to study its responsiveness to anti TNF therapy. "
01/01/2022 - "In this review, we aim to critically evaluate the mechanistic underpinnings of murine models of CD-ileitis, discuss their phenotypic similarities to human disease, and envisage their further exploitation for the development of novel targeted and personalized therapeutics."
10/01/2018 - "US Molecular Imaging Sensitively Captures Acute Ileitis Therapy Response."
10/01/2015 - "Antieosinophil therapy was also administered to the Crohn's-like ileitis model (SAMP1/SkuSlc). "
06/01/2010 - "difficile ileitis 12 days later that responded to medical therapy. "

01/01/2003 - "These results indicate that the oral administration of IS-741 inhibits neutrophil infiltration into inflamed lesions, and is effective for attenuating rat TNBS ileitis. "
12/01/2021 - "Oral administration of CN210 significantly reduced the severity of ileitis, normalized both proinflammatory MPO activity and concomitant cytokine expressions induced by indomethacin administration. "
01/01/2020 - "The in vivo effects of the SPL inhibitors 4-deoxypyridoxine hydrochloride (30 mg/L) and 2-acetyl-4 (tetrahydroxybutyl)imidazole (50 mg/L) were assessed through their oral administration to adult TNF∆ARE mice, which spontaneously develop Crohn's-like chronic ileitis. "

01/01/2019 - "Therefore, secondary abioitic mice were subjected to human fecal microbiota transplantation (FMT) and perorally infected with low-dose Toxoplasma gondii to induce subacute ileitis on day 0. "
11/01/2020 - "We conducted a series of single-donor intensive and nonintensive fecal microbiota transplantation (FMT) experiments using feces from IBD patients in remission and healthy non-IBD controls (N = 9 donors) in a mouse model of Crohn's disease (CD)-like ileitis that develops ileitis in germ-free (GF) conditions (SAMP1/YitFC; N = 96 mice). "

02/22/2016 - "Clostridium difficile ileitis in a patient, after total colectomy."
05/01/2004 - "The patient has done fairly well on routine medications, but this case represents ileitis developing post colectomy that did not exist previous to colectomy and raises the questions for the following presentations and discussions in this workshop symposium."
01/01/1991 - "As it prevents coloileal reflux, this assembly may prevent ileitis after right colectomy. "
01/01/1970 - "The natural history of post-colectomy ileitis."
01/01/2021 - "Out of 54 cases, 18 occurred within 1 month since colectomy (early ileitis), 10 later on (late ileitis) and 26 do not involve ileus (nonileitis). "

04/01/2018 - "Prepouch ileitis is associated with a significantly increased risk of pouch failure compared with the overall reported literature for restorative proctocolectomy. "
02/28/2018 - "Prepouch Ileitis After Ileal Pouch-anal Anastomosis: Patterns of Presentation and Risk Factors for Failure of Treatment."
11/01/2011 - "We investigated the impact of backwash ileitis on pouch outcome after restorative proctocolectomy with ileoanal pouch anastomosis. "
07/01/2010 - "The outcome of ileal pouch-anal anastomosis in patients with backwash ileitis is controversial. "
07/01/2010 - "A prospective analysis of clinical variables, serologic factors, and outcome of ileal pouch-anal anastomosis in patients with backwash ileitis."