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Iduronate Sulfatase

An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13.
Also Known As:
Iduronate Sulfate Sulfatase; Corrective Factor, Hunter; Factor, Hunter Corrective; Sulfatase, Iduronate; Sulfatase, Iduronate Sulfate; Sulfatase, Sulfoiduronate; Sulfate Sulfatase, Iduronate; Sulfohydrolase, Iduronatesulfate; Hunter Corrective Factor; Iduronatesulfate Sulfohydrolase; Sulfoiduronate Sulfatase; L-Iduronate-2-sulfate 2-sulfohydrolase
Networked: 37 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Fujiwara, Masako: 1 article (05/2021)
2. Hirano, Daishi: 1 article (05/2021)
3. Ida, Hiroyuki: 1 article (05/2021)
4. Iijima, Masatoshi: 1 article (05/2021)
5. Kobayashi, Hiroshi: 1 article (05/2021)
6. Oishi, Kimihiko: 1 article (05/2021)
7. Yokoi, Kentaro: 1 article (05/2021)
8. Evenstar, Laura B: 1 article (01/2017)
9. Fairbanks, Carolyn A: 1 article (01/2017)
10. Kitto, Kelley F: 1 article (01/2017)

Related Diseases

1. Mucopolysaccharidosis II (Hunter Syndrome)
2. Mucopolysaccharidoses
3. Multiple Sulfatase Deficiency Disease (Mucosulfatidosis)
4. Lysosomal Storage Diseases (Lysosomal Storage Disease)
5. Neurologic Manifestations (Neurological Manifestations)

Related Drugs and Biologics

1. Enzymes
2. Complementary DNA (cDNA)
3. Iduronidase (alpha-L-Iduronidase)
4. Hydrolases
5. Glycosaminoglycans
6. Arylsulfatases
7. N-sulfoglucosamine sulfohydrolase (sulfamidase)
8. Uronic Acids
9. Sulfates (Sulfates, Inorganic)
10. Proteins (Proteins, Gene)

Related Therapies and Procedures

1. Intravenous Administration
2. Transplantation
3. Plasma Exchange