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Iduronate Sulfatase

An enzyme that specifically cleaves the ester sulfate of iduronic acid. Its deficiency has been demonstrated in Hunter's syndrome, which is characterized by an excess of dermatan sulfate and heparan sulfate. EC 3.1.6.13.
Also Known As:
Iduronate Sulfate Sulfatase; Corrective Factor, Hunter; Factor, Hunter Corrective; Sulfatase, Iduronate; Sulfatase, Iduronate Sulfate; Sulfatase, Sulfoiduronate; Sulfate Sulfatase, Iduronate; Sulfohydrolase, Iduronatesulfate; Hunter Corrective Factor; Iduronatesulfate Sulfohydrolase; Sulfoiduronate Sulfatase; L-Iduronate-2-sulfate 2-sulfohydrolase
Networked: 28 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Nascu, Ioana: 1 article (01/2013)
2. Grigorescu-Sido, Paula: 1 article (01/2013)
3. Denes, Carmencita: 1 article (01/2013)
4. Bucerzan, Simona: 1 article (01/2013)
5. Al-Khzouz, Camelia: 1 article (01/2013)
6. Lazea, Cecilia: 1 article (01/2013)
7. Beck, Michael: 1 article (09/2011)
8. Schulze-Frenking, Gudrun: 1 article (09/2011)
9. Hoffmann, Björn: 1 article (09/2011)
10. Al-Sawaf, Sulaiman: 1 article (09/2011)

Related Diseases

1. Mucopolysaccharidosis II (Hunter Syndrome)
2. Mucopolysaccharidoses
3. Multiple Sulfatase Deficiency Disease (Mucosulfatidosis)
4. Lysosomal Storage Diseases (Lysosomal Storage Disease)
5. Mucolipidoses (Sialidosis)

Related Drugs and Biologics

1. Complementary DNA (cDNA)
2. Iduronidase (alpha-L-Iduronidase)
3. Sulfates (Sulfates, Inorganic)
4. Staphylococcal Protein A (A, Protein)
5. Heparitin Sulfate (Heparan Sulfate)
6. DNA (Deoxyribonucleic Acid)
7. Disaccharides
8. Arylsulfatases
9. Antibodies
10. O-(alpha-idopyranosyluronic acid)-(1-3)-2,5-anhydroalditol-4-sulfate

Related Therapies and Procedures

1. Plasma Exchange
2. Transplantation (Transplant Recipients)