|1.||Psoriasis (Pustulosis Palmaris et Plantaris)
|4.||Lichen Planus (Lichen Ruber Planus)
|5.||Lamellar Ichthyosis (Harlequin Ichthyosis)
|1.||Fischer, Judith: 15 articles (01/2015 - 03/2006)|
|2.||Akiyama, Masashi: 13 articles (07/2015 - 11/2003)|
|3.||Traupe, Heiko: 12 articles (02/2014 - 02/2003)|
|4.||Vahlquist, Anders: 12 articles (04/2013 - 01/2003)|
|5.||Elias, Peter M: 9 articles (04/2015 - 04/2004)|
|6.||Oji, Vinzenz: 9 articles (02/2014 - 07/2006)|
|7.||Richard, Gabriele: 9 articles (11/2011 - 03/2003)|
|8.||Hausser, Ingrid: 8 articles (01/2015 - 04/2009)|
|9.||Sprecher, Eli: 8 articles (04/2011 - 04/2003)|
|10.||Shimizu, Hiroshi: 8 articles (10/2010 - 11/2003)|
01/01/2013 - "Careful surveillance and management of mucous membrane, laboratory, skeletal, and teratogenic side effects has made systemic retinoids the mainstay of therapy for ichthyosis and related skin types."
01/01/2013 - "Systemic retinoids in the management of ichthyoses and related skin types."
11/01/2007 - "If an ichthyosis cannot be controlled by topical therapy alone, retinoids can be used. "
09/01/1986 - "[Retinoids in the treatment of ichthyosis]."
03/01/1984 - "These results demonstrate that (1) the synthetic retinoids hold promise as topical agents; (2) irritation is not an absolute requirement for topical retinoid activity; and (3) the diazacholesterol-fed mouse offers a new assay of topical retinoid potency in a well-defined animal model of ichthyosis."
|2.||tazarotene (Tazorac)FDA Link
10/01/1999 - "Short-term topical application of tazarotene 0.05% gel is a very effective and well-tolerated treatment modality in different forms of congenital ichthyoses and may be an alternative to systemic retinoid therapy."
01/01/2006 - "[Topical tazarotene for severe congenital ichthyosis]."
10/01/1999 - "The clinical efficacy and tolerability of the topical receptor-selective retinoid tazarotene in the treatment of congenital ichthyoses was investigated. "
10/01/1999 - "Effect of topical tazarotene in the treatment of congenital ichthyoses."
05/01/2013 - "We describe a patient with recessive ichthyosis for whom daily application of topical tazarotene produced rapid and persistent improvement of bilateral lower eyelid ectropion without adverse effects. "
|3.||Urea (Carbamide)FDA LinkGeneric
01/01/1998 - "Efficacy of urea therapy in children with ichthyosis. "
01/01/1998 - "The analysis of the global estimation of severity of ichthyosis showed improvements being stronger in the body areas treated with Laceran 10% urea lotion (from 4.8 to 2.0 points) than in the areas treated with the urea-free Laceran lotion base (from 4.8 to 2.5 points). "
01/01/1989 - "[Urea and urea combinations in ichthyoses]."
04/01/1982 - "The use of 25 percent urea in an emollient lotion appears to relieve the ichthyosis and, consequently, encourages the continued use of this drug."
12/01/1970 - "The treatment of ichthyosis and hyperkeratotic conditions with urea."
01/01/1985 - "The authors show the noteworthy efficacy of the aromatic retinoid Ro 10-9359 in the treatment of ichthyosis linearis circumflexa. "
01/01/1984 - "Light and electron microscopy study of ichthyosis and its evolution with oral etretinate treatment]."
10/01/1992 - "Bone changes and their significance in children with ichthyosis on long-term etretinate therapy."
01/01/1987 - "At 12, treatment with etretinate failed to improve the ichthyosis. "
01/01/1985 - "[Comèl's ichthyosis linearis circumflexa: treatment with Ro 10-9359. "
|5.||Tacrolimus (Prograf)FDA LinkGeneric
03/01/2000 - "A case of ichthyosis linearis circumflexa successfully treated with topical tacrolimus."
05/01/2001 - "Case reports document efficacy in recalcitrant pyoderma gangrenosum, mucosal lichen planus, and ichthyosis linearis trolled trials and case reports indicate oral tacrolimus is effective in recalcitrant plaque psoriasis. "
01/01/2002 - "It has also been suggested that topical tacrolimus is useful in the treatment of alopecia areata, erosive lichen planus, isolated ichthyosis linearis circumflexa, steroid-induced rosacea, and in the prevention of allograft rejection, however more clinical trials need to be performed."
06/01/2003 - "We report a case of acquired ichthyosis with original clinical features and we propose to coin the term "acquired circinated ichthyosis". "
08/01/1995 - "A few cases of acquired ichthyosis associated with SLE has been reported, and ichthyosis developed only in active stage of SLE. "
01/01/2009 - "Pityriasis rotunda is a disorder of keratinization, which is thought to be a form of acquired ichthyosis, a delayed presentation of congenital ichthyosis, or a cutaneous manifestation of systemic disease. "
01/01/2010 - "We report a 45-year-old woman with a several year history of dyspnea on exertion and panuveitis who presented to a county hospital with acquired lower extremity ichthyosis and a biopsy consistent with both acquired ichthyosis and noncaseating, granulomatous sarcoidosis. "
07/01/2010 - "We describe a child with acquired ichthyosis in whom an autoimmune hypothyroidism was detected; furthermore, replacement therapy with L-thyroxine resulted in complete remission of ichthyosis."
08/01/2002 - "At that time he also had widespread mild ichthyosis that cleared completely with the use of emollients. "
11/01/2000 - "The patient was treated with emollients (aquaphor) twice daily with continuing improvement in ichthyosis. "
01/01/2015 - "Like for other congenital ichthyoses, topical treatments (mainly emollients and keratolytics) are symptomatic and offer only temporary relief. "
01/01/2014 - "Controlling symptoms with emollients is the goal of treatment for ichthyosis since it has no cure. "
01/01/2013 - "A newborn with congenital ichthyosis cared for in our clinic failed his initial treatment of topical emollients. "
|8.||calcipotriene (calcipotriol)FDA LinkGeneric
10/01/1994 - "We investigated the clinical efficacy of topically applied calcipotriol in six patients with congenital ichthyosis, using a double-blind, bilaterally paired, comparative approach. "
09/01/1997 - "Recent reports suggest that certain ichthyoses (particularly the hyperproliferative variants) and keratodermas may respond to topical calcipotriene ointment. "
05/01/1995 - "Short-term treatment with calcipotriol ointment (50 micrograms/g) used in amounts up to about 100 g/wk is moderately efficacious, well-tolerated, and safe in adult patients with various ichthyoses."
05/01/1995 - "At the end of the treatment regimen, calcipotriol ointment had an effect on the improvement of the ichthyoses, although to a variable degree. "
10/01/1994 - "Effect of topical calcipotriol on congenital ichthyoses."
05/01/2007 - "The results of this trial warrant further clinical trials to confirm efficacy and safety of liarozole as an orphan drug in ichthyosis."
03/01/2005 - "Topical liarozole in ichthyosis: a double-blind, left-right comparative study followed by a long-term open maintenance study."
01/01/1997 - "This open study showed that oral liarozole treatment was efficacious and well tolerated in the treatment of different types of ichthyosis. "
01/01/1997 - "Twelve male patients with ichthyosis were given oral liarozole, 150 mg twice daily, in an open study for 12 weeks. "
10/01/2001 - "Liarozole has already been found to be effective in the treatment of retinoid-responsive conditions such as chronic plaque psoriasis and ichthyoses. "
|10.||Vitamin A (Retinol)FDA LinkGeneric
11/01/1953 - "[Electroencephalographic study of a case of congenital ichthyosis before and after vitamin A therapy]."
01/01/1990 - "The liver damage in these patients was secondary to chronic ingestion of massive doses of vitamin A for congenital ichthyosis. "
08/01/1980 - "A female patient with congenital ichthyosis took vitamin A in an uncontrolled manner throughout 3 years totalling 60 Mill. "
03/01/1973 - "[Local application of vitamin A in the treatment of congenital ichthyosis and inchtyosis connected to the sex of the patient]."
11/01/1971 - "[Histochemical changes in the skin of patients with ichthyosis during treatment with vitamin A]."
|1.||Homologous Transplantation (Allograft)
|2.||Hydrotherapy (Whirlpool Bath)
11/01/2011 - "To assess the short- and medium-term efficacy of hydrotherapy on QoL and clinical symptoms of patients with inherited ichthyosis. "
11/01/2011 - "Short- and medium-term efficacy of specific hydrotherapy in inherited ichthyosis."
11/01/2011 - "In this 9-month prospective, open-label, multicentre study, 20 children and 24 adults with ichthyosis were enrolled in several French reference and competence centres, 2 months before undergoing a 3-week treatment with specific hydrotherapeutic management at Avène Hydrotherapy Centre. "
11/01/2011 - "A 3-week treatment at Avène Hydrotherapy Centre provided significant and persisting improvement of QoL and clinical symptoms in patients with inherited ichthyoses."
11/01/2011 - "At baseline (2 months before hydrotherapy), beginning (D0) and end of hydrotherapy (D18), and 3 and 6 months later at the reference and competence centres, patients self-assessed QoL using the Dermatology Life Quality Index (DLQI) or its paediatric version (Children's DLQI), and investigators evaluated ichthyosis severity using a specific clinical ichthyosis score. "
01/01/2010 - "Living related hemi-face skin transplant using radial forearm free flap for a xeroderma pigmentosa patient: early outcome."
06/01/2013 - "Owing to cholestasis, severe intractable pruritus, and poor quality of life, he underwent a living-related liver transplant from his mother, and his ichthyosis and pruritus dramatically improved. "
01/01/2008 - "Vitiligo, psoriasis, alopecia areata, contact hypersensitivity, lichen planus, pyoderma gangrenosum, ichthyosis linearis circumflexa, and skin grafting/transplant are a few unapproved indications and uses, in addition to miscellaneous dermatoses. "
02/01/1997 - "We analyzed DNA extracted from 39 keratoacanthomas from 22 "at-risk" patients (nine patients undergoing UV light and/or anthralin therapy for psoriasis, 10 solid organ transplant recipients, one patient with xeroderma pigmentosa, one patient with acquired immunodeficiency syndrome, and one patient undergoing therapy for non-Hodgkin's lymphoma) for the presence of HPV. "
04/01/1986 - "It is recommended that when ichthyosis uteri is detected the uterus should be removed, since the changes cannot be eliminated by curettage and there is a risk of malignant degeneration within a relatively short time."
01/01/2011 - "Here, we present two cases of ichthyosis uteri that were both diagnosed in the curettage material. "
02/01/2012 - "Cochlear implantation in keratitis-ichthyosis-deafness syndrome: 10-year follow-up of two patients."
02/01/2010 - "A novel dominant and a de novo mutation in the GJB2 gene (connexin-26) cause keratitis-ichthyosis-deafness syndrome: implication for cochlear implantation."
06/01/2008 - "Cochlear implantation and connexin expression in the child with keratitis-ichthyosis-deafness syndrome."
02/01/2012 - "The objective of this study was to describe long-term outcomes after cochlear implantation in keratitis-ichthyosis-deafness (KID) syndrome, often caused by GJB2 mutations, in the context of other reported cases. "
09/01/2009 - "Cochlear implantation in children with keratitis-ichthyosis-deafness (KID) syndrome: outcomes in three cases."