Iatrogenic Disease

Any adverse condition in a patient occurring as the result of treatment by a physician, surgeon, or other health professional, especially infections acquired by a patient during the course of treatment.

Also Known As:

Hospital-Acquired Condition; Condition, Hospital-Acquired; Conditions, Hospital-Acquired; Disease, Iatrogenic; Diseases, Iatrogenic; Hospital Acquired Condition; Hospital-Acquired Conditions; Iatrogenic Diseases

Networked: 278 relevant articles (4 outcomes, 6 trials/studies)

Relationship Network

Disease Context: Research Results

Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10023
  - Disease Attributes: 18
    - Iatrogenic Disease: 278
      - Cross Infection: 8345

Related Diseases

1.	Infections
2.	Overweight
3.	Vascular Diseases (Vascular Disease)
4.	Sleep Apnea Syndromes (Sleep Apnea)
5.	Hypoglycemia (Reactive Hypoglycemia)

Experts

1.	Naisbitt, Dean J: 4 articles (01/2021 - 02/2013)
2.	Pirmohamed, Munir: 3 articles (01/2021 - 02/2013)
3.	Diebo, Bassel G: 3 articles (06/2020 - 11/2018)
4.	Hassanzadeh, Hamid: 3 articles (06/2020 - 11/2018)
5.	Horn, Samantha R: 3 articles (06/2020 - 11/2018)
6.	Lafage, Renaud: 3 articles (06/2020 - 11/2018)
7.	Lafage, Virginie: 3 articles (06/2020 - 11/2018)
8.	Oh, Cheongeun: 3 articles (06/2020 - 11/2018)
9.	Passias, Peter G: 3 articles (06/2020 - 11/2018)
10.	Segreto, Frank A: 3 articles (06/2020 - 11/2018)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Iatrogenic Disease:

1.	Chloroquine (Aralen)FDA LinkGeneric 06/01/1978 - "To our knowledge very delayed onset of chloroquine retinopathy is a relatively rare phenomenon but the medical and ophthalmic communities must be alerted to the possibly severe complications of this iatrogenic disease entity." 05/01/1965 - "[Chloroquine retinopathy: a serious iatrogenic disease]." 02/01/2007 - "Retinal toxicity due to chloroquine is an uncommon iatrogenic disease. "
2.	Estrogens (Estrogen)FDA Link 03/01/1977 - "Although this iatrogenic disease should be virtually eliminated with the monitoring of daily urinary estrogens, severe hyperstimulation may still occur as a result of laboratory error." 01/01/1991 - "Successively evidence of iatrogenic disease due to estrogens has accumulated but total consensus has not yet been reached. "
3.	Indicators and Reagents (Reagents)IBA 01/01/2021 - "For inpatient procedures, the number and rate of admissions with a hospital-acquired condition (HAC) or patient safety indicator event (PSIs), as well as the unadjusted and adjusted difference in mean LOS and Medicare costs between admissions with and without a HAC/PSI. " 01/01/2020 - "The US Centers for Medicare and Medicaid Services have used Patient Safety Indicator 90 (PSI90), a composite rate of hospital-acquired conditions (HACs), to adjust payments and score hospitals on quality since 2015. " 08/01/2018 - "A descriptive survey design was conducted, with hospital-acquired conditions (HACs) used as an indicator of effectiveness of care. " 02/01/2008 - "Utility and accuracy of claims data for identifying hospital-acquired conditions, including POA indicator variables, requires close attention be paid by clinicians and coders to what is being recorded." 03/01/2004 - "The assessment was based on a medical records indicator that differentiated hospital-acquired conditions from preexisting comorbidities. "
4.	IronIBA 02/01/2017 - "Patients considered unresponsive to iron therapy were those who left the study, were not assessed because the study's timeframe ended, still had an iron deficiency because they did not continuously take the medication, or suffered from somatic diseases which explains their resistance to treat the low iron level (nutritional imbalance, digestive or urinary or gynecological or iatrogenic diseases, sleep apnea). "
5.	Glucose (Dextrose)FDA LinkGeneric 03/01/2017 - "This study evaluated time required to achieve BG control (<180 mg/dL; <140 mg/dL for cardiovascular surgery patients); hypoglycemia incidence (<70 and <40 mg/dL); glucose variability (assessed by SD and coefficient of variation percentage [CV%]); excursions (BG levels >180 mg/dL after control attained); and the impact of eGMS on hospital-acquired condition (HAC)-8 rates. " 03/01/2017 - "BG = blood glucose CMS = Centers for Medicare and Medicaid Services CV = coefficient of variation CV% = coefficient of variation percentage eGMS = electronic glucose management system GV = glycemic variability HAC = Hospital-Acquired Condition ICU = intensive care unit IU = intermediate unit IV = intravenous LOS = length of stay VMC = Vidant Medical Center."
6.	AminorexIBA 01/01/1982 - "This study is concerned with a group of 31 female patients who suffered from a terminal vascular disease (primary vascular pulmonary hypertension)--an iatrogenic disease which with high probability is the consequence of a drug for weight reducing (Menocil), prescribed by their family doctors to these moderate overweight middle aged women. "
7.	SteroidsIBA 02/01/2011 - "Steroid-induced iatrogenic disease after treating for pseudothrombocytopenia." 07/12/1975 - "Thus, chronic treatment with steroids is invariably associated with side effects, but there are a number of therapeutic rules whose strict observance may prevent a patient in chronic need of steroid treatment from developing a second, iatrogenic disease. " 11/01/1998 - "Symptomatic epidural lipomatosis is probably underestimated because physicians concerned by steroid treatment are not fully informed about this potentially severe and usually iatrogenic disease. " 04/01/1979 - "Obstructive uropathy, immobilization, urinary stasis and infection, previously undiagnosed urologic anomalies, steroid therapy, milk-alkali syndrome, iatrogenic disease and endemic disease have contributed to stone formation. " 03/01/1967 - "[Iatrogenic diseases due to hormone preparations--steroids, weight-reducing drugs and oral contraceptives]."
8.	Hormones (Hormone)IBA 03/01/1967 - "[Iatrogenic disease caused by the use of hormones in pediatrics]." 07/01/1964 - "[ADRENOCORTICOSTEROID HORMONES AND IATROGENIC DISEASE]." 09/01/1966 - "[Iatrogenic diseases in hormone therapy]." 05/01/1999 - "Despite these advances, we have seen in recent years 3 potentially preventable outbreaks of disease: iatrogenic Creutzfeldt-Jakob disease due to contaminated pituitary hormone extracts and dura mater grafts, and a new variant of the disease (Will-Ironside syndrome) linked to consumption of beef contaminated by the agent of bovine spongiform encephalopathy, underscoring the disparity between fundamental knowledge and its practical application." 03/01/1967 - "[Iatrogenic diseases due to hormone preparations--steroids, weight-reducing drugs and oral contraceptives]."
9.	Contrast MediaIBA 12/01/2012 - "Contrast-induced nephropathy is an iatrogenic disease caused by the administration of iodinated contrast material to certain at-risk patients. " 10/01/2007 - "Radiological procedures requiring intravascular administration of iodinated contrast media are becoming a common source of an iatrogenic disease known as contrast-induced nephropathy (CIN). " 01/01/2007 - "Radiological procedures require the intravascular administration of iodinated contrast media, which are becoming a great source of an iatrogenic disease known as contrast-induced nephropathy. " 12/01/2014 - "Nephrogenic systemic fibrosis (NSF) is a severe iatrogenic disease that affect patients with impaired renal function exposed to gadolinium-based contrast agents. " 05/01/2008 - "In conclusion, nephrogenic systemic fibrosis is a serious iatrogenic disease of patients with renal insufficiency caused by some Gd-containing contrast agents, in particular gadodiamide. "
10.	Anti-Bacterial Agents (Antibiotics)IBA 04/01/1969 - "[Antibiotics and iatrogenic diseases]." 07/01/1958 - "Antibiotics and iatrogenic disease." 09/01/1966 - "[Iatrogenic diseases in chemotherapy with special reference to antibiotics]." 03/01/1997 - "Pseudomembranous colitis (PMC) is a frequently severe, sometimes fatal iatrogenic disease that is antibiotic-associated in almost all cases. " 02/01/1984 - "Although the records of our case did not specify what medication was placed in the lesion, clinicopathologic features further supported the hypothesis that myospherulosis may be a unique instance of iatrogenic disease caused by petrolatum-based antibiotic ointments."

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 04/01/1972 - " iatrogenic disease due to drug therapy is to be recognized or prevented the communication of information about drugs must be improved." 01/01/1988 - "The analysis suggested high frequency rate for iatrogenic diseases promoted by surgical interventions and chemotherapy. " 12/01/1976 - "Iatrogenic disease: a hazard of multiple drug therapy." 02/01/1968 - "[Problem of current drug therapy and iatrogenic diseases]." 01/01/1968 - "With special reference to iatrogenic diseases caused by drug therapy]."
2.	Surgical Instruments (Clip) 01/01/2004 - "The widespread distribution of infectivity in lymphoid tissues in vCJD has lead to concerns over the possibility of iatrogenic disease transmission by contaminate surgical instruments, or by blood transfusion. " 06/01/2012 - "No new sources of disease have been identified, and current practices, which combine improved recognition of potentially infected persons with new disinfection methods for fragile surgical instruments and biological products, should continue to minimize the risk for iatrogenic disease until a blood screening test for the detection of preclinical infection is validated for human use." 10/15/1991 - "Searches of MEDLINE for articles published from 1980 to 1990 on disinfection, sterilization, cross infection, surgical instruments and iatrogenic disease, bibliographies, standard texts and reference material located in a central processing department. "
3.	Length of Stay 05/17/2023 - "Predicting length of stay (LoS) and understanding its underlying factors is essential to minimizing the risk of hospital-acquired conditions, improving financial, operational, and clinical outcomes, and better managing future pandemics. " 01/01/2021 - "Inpatients with extended length of stay (LOS), referred to as LOS outliers, pose a challenge to health systems by contributing to high costs while assuming all the risks associated with hospital-acquired conditions. " 01/01/2021 - "Outcomes included discharge disposition, hospital length of stay, intensive care unit length of stay, hospital-acquired conditions, and cost (total and per diem). " 01/01/2021 - "The association between SNH status and in-hospital mortality, discharge disposition, complications, hospital-acquired conditions (HACs), length of stay (LOS), and costs were assessed. " 01/01/2021 - "Length of stay beyond medical readiness (LOS-BMR) leads to increased expenses and higher morbidity related to hospital-acquired conditions. "
4.	Therapeutics 07/01/2006 - "Since patients with factitious disease present a false medicalhistory, their physicians prescribe unnecessary procedures and therapies that may result in iatrogenic disease. " 07/01/2004 - "An undetermined but extended life expectancy, afforded by anti-retroviral therapies, is understood against risk of iatrogenic diseases and/or viral drug resistance. " 05/01/1992 - "[Iatrogenic diseases in an intensive therapy unit: a theoretical approach]." 07/01/1991 - "The growing number of drugs used to treat various diseases and the growing number of invasive procedures used for diagnosis and therapy have generated many iatrogenic diseases. " 12/01/1976 - "The term ''iatrogenic disease'' means disease caused by therapy prescribed by doctors. "
5.	Nursing Care 09/08/1982 - "Nursing care study: iatrogenic disease." 04/01/2014 - "Over the past 15 years, the model of medical and nursing care changed from being exclusively oriented to the diagnosis and treatment of acute illness, to the achievement of outcomes by preventing iatrogenic complications (Hospital Acquired Conditions). " 08/01/1982 - "[Iatrogenic disease: implications for nursing care]." 01/01/2021 - "Nonventilator hospital-acquired pneumonia (NV-HAP) is a common hospital-acquired condition that is amenable to basic nursing care interventions. "