|2.||Chronic Obstructive Pulmonary Disease (COPD)
|3.||Asthma (Bronchial Asthma)
|4.||Respiratory Insufficiency (Respiratory Failure)
|5.||Airway Obstruction (Choking)
|1.||Weese-Mayer, Debra E: 14 articles (05/2015 - 11/2005)|
|2.||Berry-Kravis, Elizabeth M: 8 articles (09/2012 - 11/2005)|
|3.||Rand, Casey M: 7 articles (09/2014 - 01/2009)|
|4.||Patwari, Pallavi P: 7 articles (08/2014 - 04/2010)|
|5.||Amiel, Jeanne: 5 articles (01/2016 - 04/2008)|
|6.||Carroll, Michael S: 5 articles (09/2014 - 04/2010)|
|7.||Straus, Christian: 5 articles (05/2014 - 04/2008)|
|8.||Windisch, Wolfram: 5 articles (04/2013 - 04/2003)|
|9.||McNicholas, W T: 4 articles (04/2015 - 10/2002)|
|10.||Fauroux, Brigitte: 4 articles (03/2015 - 06/2009)|
06/01/1990 - "We explained the increase in PaO2 during exercise by three nonmutually exclusive mechanisms: 1) an increase in the respiratory quotient; 2) the exercise induced increase in alveolar ventilation, although inadequate to match the increase in CO2 production, would be redistributed to previously poorly ventilated regions of the lung, these regions therefore receiving enough oxygen to arterialize the blood flowing through the alveolar capillaries; 3) alternatively, perfusion would be redistributed in a more efficient way during exercise, so that even in the presence of hypoventilation, oxygenation would be improved."
12/02/2008 - "During the follow-up for 22 and 12 months respectively after discharge, PSG showed that the alveolar hypoventilation-induced long period oxygen desaturation at sleep had been greatly improved, and echocardiogram showed that the pulmonary pressure was greatly decreased. "
04/01/2013 - "The aim of this study was to measure the masking effect of oxygen supplementation in SpO2 when alveolar hypoventilation develops during sedated endoscopy. "
11/01/2004 - "This two-part study was designed to determine the effect of supplemental oxygen on the detection of hypoventilation, evidenced by a decline in oxygen saturation (Spo(2)) with pulse oximetry. "
01/01/1999 - "This study demonstrates that lung tissue PO2 registrations can be made in a suitable animal (pig) model, and that hypoventilation induced an almost reversible decrease in lung tissue oxygen pressure distributions. "
03/01/2000 - "Study goals were to determine whether transcutaneous carbon dioxide (PtcCO(2)) monitoring during endoscopic retrograde cholangiopancreatography (ERCP) prevents severe hypoventilation and to assess the accuracy of clinical observation and pulse oximetry in detecting hypoventilation. "
10/01/1998 - "However, recent studies using phrenic nerve stimulation to test the force produced by the diaphragm show that carbon dioxide retention (hypoventilation) and voluntary cessation of loading occur before the muscles become overtly fatigued."
04/01/2015 - "Transcutaneous carbon dioxide tension (PtcCO2) rose by 2.56 ± 1.59 kPa overnight (P = 0.001), suggesting hypoventilation. "
03/01/2015 - "The recent scoring rules of the American Academy of Sleep Medicine (AASM) define hypoventilation in children as a carbon dioxide (CO2) level of >50 mmHg for >25 % of total sleep time (partial pressure of CO2 (PCO2) > 50[>25 %]). "
07/01/2014 - "Because undetected hypoventilation is a common pathway for complications, capnographic monitoring of exhaled carbon dioxide has been advocated. "
08/01/2012 - "Central hypoventilation syndrome (CHS) is a rare condition characterized by hypoventilation during sleep, reduced ventilatory responsiveness to CO(2) and O(2), impaired perception of air hunger, and autonomic abnormalities. "
01/01/2012 - "Although it was well tolerated, the BVM was subjectively more difficult to breathe through and was associated with greater mask pressures and a small increase in F(E)CO(2) consistent with hypoventilation or rebreathing. "
04/01/2011 - "Transcutaneous CO(2) monitors (P(tcCO(2))) provide a noninvasive correlate of P(aCO(2)), but their accuracy and stability over extended monitoring have been considered inadequate for the diagnosis of hypoventilation. "
06/01/2009 - "In some patients the first laboratory clue that chronic hypoventilation is present is to note an unexplained elevation in the serum CO (2) (HCO (3)) on routine electrolyte testing. "
06/01/2009 - "HCTs were performed on 19 adult patients with KS and/or NMD (age 22-73 years, forced expiratory volume in 1 s (FEV(1)) 0.76, forced vital capacity (FVC) 0.92, SaO(2) 95%, partial pressure of arterial CO(2) (PaCO(2)) 5.7 kPa) who were at risk for nocturnal hypoventilation. "
|4.||Lactic AcidFDA LinkGeneric
01/01/1988 - "The purpose of the present study was to investigate the blood lactate (LA-) responses to hypoventilation induced by reduced frequency breathing (RFB) during recovery from exercise. "
05/01/1995 - "Hypoventilation while wearing masks caused higher amounts of blood lactate accumulation. "
04/01/2013 - "Lung hyperinflation, deoxygenation, hypoventilation, blood lactate production, dyspnea and the time needed to manage stair climbing were not improved by the application of CPAP (all p > 0.05). "
01/01/2014 - "Hypoventilation, hyperventilation, FiO2 ≥ 0.80, the need for high doses of inotropic support, and high levels of lactic acid were the most important post-return of spontaneous circulation factors associated with in-hospital mortality in children in our population."
12/01/1998 - "Because lactate infusion induces a metabolic alkalosis, one would rather expect a compensatory hypoventilation. "
|5.||Morphine (MS Contin)FDA LinkGeneric
01/01/1997 - "This study was done to determine if chronic intermittent in utero exposure to morphine (MOR) during the last half of gestation results in hypoventilation and decreased ventilatory sensitivity to CO2 in the neonate. "
10/01/2013 - "Morphine (2 mg/kg, i.v.) elicited sustained decreases in arterial blood pH, pO₂ and sO₂, and increases in pCO₂ (all responses indicative of hypoventilation) and alveolar-arterial gradient (indicative of ventilation-perfusion mismatch). "
07/12/2010 - "For example, overdose of morphine causes hypoventilation, an inadequate ventilation to perform gas exchanges in lungs leading to increased CO2 concentration in the blood. "
01/01/2010 - "The main trigger was a morphine overdose with volume contraction due to vomiting and a further aggravation of chronic compensatory elevation of bicarbonate due to hypoventilation leading to MAS; thus, suggesting hypoventilation as a risk factor for MAS."
07/01/1981 - "One patient suffered sudden chest pain shortly after an injection of morphine, and one patient had moderate hypoventilation after buprenorphine; both patients recovered uneventfully. "
02/01/1985 - "Alveolar hypoventilation treated with medroxyprogesterone."
09/01/2002 - "This case documents the treatment of chronic type II respiratory failure secondary to central hypoventilation with medroxyprogesterone, a new treatment option."
07/01/1995 - "Medroxyprogesterone has been shown to be especially useful in patients with an obesity-hypoventilation component to their disease. "
09/01/1998 - "Although more controlled studies would be helpful, relatively clear-cut indications for the use of ventilatory stimulants exist for hypercapnic obesity-hypoventilation patients (medroxyprogesterone), myxedema (thyroid replacement), central apnea (acetazolamide), and periodic breathing in congestive heart failure (theophylline). "
01/01/1983 - "Almitrine bismesylate in congenital central hypoventilation."
01/01/1983 - "Use of almitrine bismesylate to stimulate ventilation in congenital central hypoventilation."
01/01/1980 - "[Importance of almitrine in the management of post-anesthetic hypoventilation]."
01/01/1980 - "At FiO2 = o.22, almitrine partially corrected hypoventilation. "
04/01/1983 - "The findings are consistent with an agonist action of almitrine in the peripheral chemoreceptors and suggest that it may have clinical value in managing respiratory failure due to hypoventilation."
|8.||Halothane (Fluothane)FDA Link
07/01/1988 - "Controlled hypoventilation at 1.2% halothane increased the variables significantly. "
07/01/1988 - "Renal sympathetic nerve activity (rSNA), mean arterial pressure (MAP) and heart rate (HR) were measured in the conscious state and at the inspiratory halothane concentrations of 0.6%, 1.2% and 2.4% in one mechanically normoventilated and one spontaneously breathing group, while a third group was subjected to controlled hypoventilation at 1.2% halothane concentration. "
10/01/1976 - "In 35 patients carotid angiography was performed under general anaesthesia (Halothane or NLA) under hyper- and hypoventilation conditions. "
12/01/1984 - "Methoxyflurane caused significantly greater (P less than 0.05) hypoventilation than halothane only at 2.0 MAC. "
05/01/2002 - "In the immediate post operative period atmospheric oxygen might become inadequate for a number of reasons including hypoventilation due to central pharmacological depression, diffusion hypoxia and increased metabolic rate due to shivering (the so called halothane shakes)."
|9.||Pancuronium (Pavulon)FDA LinkGeneric
11/01/1984 - "Pancuronium administration and immediate hypoventilation."
03/01/1988 - "4 cmH2O) immediately prior to paralysis effectively prevented the hypoventilation previously associated with the administration of the first dose of pancuronium."
01/01/1990 - "In eight anesthetized mongrel dogs with thiopental, diazepam and pancuronium bromide, ECMO with arterio-venous shunt was performed under hypoventilation for 24 hours. "
08/01/1992 - "The risk of intraoperative hypoventilation and hypoxemia was eliminated, yet, due to the lack of adequate monitoring techniques the slow recovery from curare, alcuronium or pancuronium neuromuscular blockade was hardly appreciated.(ABSTRACT TRUNCATED AT 400 WORDS)"
|10.||Narcotics (Narcotic Analgesics)IBA
03/01/2006 - "Hypoventilation due to narcotics with subsequent hypercarbia and blood-brain barrier breaching may be implicated in the pathogenesis of this complication."
02/01/1986 - "Hypoventilation, respiratory acidosis, and hypoxemia in the groups given narcotics improved significantly with time, presumably because of drug clearance. "
02/01/1986 - "Hypoventilation in the groups given narcotics resulted from significant reductions (P less than 0.05) in the respiratory rate and VE and produced significant (P less than 0.05) respiratory acidosis and hypoxemia. "
06/01/1992 - "Although desaturations related to narcotic analgesics and sedatives are most likely due to hypoventilation, the mechanism in women treated with magnesium sulfate is uncertain. "
|1.||Artificial Respiration (Mechanical Ventilation)
01/01/2007 - "To examine the efficacy of nocturnal mechanical ventilation in relieving hypoventilation related symptoms and in prolonging survival in people with neuromuscular or chest wall disorders. "
08/01/2000 - "Mechanical ventilation at home with nasal or tracheal intermittent positive pressure resulted in improved chronic hypoventilation. "
01/01/2000 - "To examine the efficacy of nocturnal mechanical ventilation in relieving hypoventilation related symptoms in patients with neuromuscular or chest wall disorders. "
01/01/2014 - "We searched for quasi-randomised or randomised controlled trials of participants of all ages with neuromuscular or chest wall disorder-related stable chronic hypoventilation of all degrees of severity, receiving any type and any mode of long-term nocturnal mechanical ventilation. "
11/01/2008 - "Randomised trial of inpatient versus outpatient initiation of home mechanical ventilation in patients with nocturnal hypoventilation."
|2.||Mechanical Ventilators (Ventilator)
01/01/2012 - "The Respironics V60 Ventilator, in the average volume-assured pressure support mode, was attached to our patient and improved and stabilized his sleep-related hypoventilation by automatically adjusting force to within an acceptable range. "
07/01/1989 - "Ventilator support produces clinical improvement in late cases with symptomatic hypoventilation. "
05/01/2014 - "In a randomized crossover trial, we tested the hypothesis that iVAPS, with automated selection of ventilator settings, was non-inferior to standard PS ventilation, with settings determined by an experienced health-care professional, for controlling nocturnal hypoventilation in patients naive to NIV. "
06/01/2010 - "The aim of the study was to evaluate the ability of home ventilators to maintain a minimal tidal volume during different conditions associated with alveolar hypoventilation. "
03/01/2009 - "In total, 20 neuromuscular and chest wall disease patients with nocturnal hypoventilation treated with long-term NIV completed a randomised crossover trial comparing two noninvasive pressure support ventilators: a standard bilevel ventilator (VPAP III) and a novel autotitrating bilevel ventilator (AutoVPAP). "
|3.||Positive-Pressure Respiration (PEEP)
12/01/1997 - "To compare the efficacy of positive pressure ventilation applied through a mask versus an endotracheal tube, using anesthetized/paralyzed foals as a model for foals with hypoventilation. "
12/01/2014 - "In conclusion, a single, split-night polysomnogram is frequently inconclusive for the assessment of nocturnal hypoventilation and complete titration of non-invasive positive pressure ventilation in patients with ALS. "
01/01/2011 - "[Possibilities of bi-level positive pressure ventilation in chronic hypoventilation]."
11/01/2010 - "Hypoventilation is typically treated with positive pressure ventilation or, in extreme cases, by phrenic nerve stimulation. "
10/15/2010 - "Noninvasive positive pressure ventilation (NPPV) devices are used during sleep to treat patients with diurnal chronic alveolar hypoventilation (CAH). "
|4.||Continuous Positive Airway Pressure
02/01/2014 - "Hypercapnic hypoventilation due to tracheobroncomalacia: the success of non-invasive respiratory support with continuous positive airway pressure."
08/15/2006 - "Since central hypoventilation progresses in the course of MSA, the choice of NPPV rather than continuous positive airway pressure should be encouraged to treat laryngeal contraction disorder associated with MSA."
02/01/1994 - "[Management of nocturnal nasal mask continuous positive airway pressure in central hypoventilation in patients with respiratory diseases]."
06/01/2007 - "This chapter addresses the use of long-term non-invasive positive pressure ventilation (NIPPV) (to the exclusion of continuous positive airway pressure) in the different clinical settings in which it is currently proposed: principally in diseases responsible for hypoventilation characterized by elevated PaCO(2). "
02/01/2010 - "Non invasive ventilation used during sleep is the most appropriate approach to reverse the consequences of nocturnal hypoventilation, although continuous positive airway pressure (CPAP) may be effective in those individuals where a significant degree of upper airway obstruction is present. "
|5.||Intermittent Positive-Pressure Ventilation
12/01/2015 - "Via a single nasal prong (4-mm internal diameter, 6- to 7-cm depth), positive pressure was delivered from the outset, with nasal intermittent positive pressure ventilation (NIPPV) used until transition to nasal CPAP was attempted, and periodically thereafter for hypoventilation. "
12/01/2000 - "Long-term nocturnal nasal intermittent positive pressure ventilation (NIPPV) has beneficial effects on daytime PaCO2 in patients with chronic alveolar hypoventilation. "
12/01/2000 - "Ventilatory response to CO2 re-breathing before and after nocturnal nasal intermittent positive pressure ventilation in patients with chronic alveolar hypoventilation."
04/01/1999 - "Beside the improvement of life quality and extension of life time the aim of IPPV is a reduction of the secondary effects of chronic hypoventilation in order to stabilize the symptoms. "
03/01/1993 - "A new nasal mask for nocturnal, intermittent positive pressure ventilation was used by patients with symptomatic sleep hypoventilation due to chronic neuromuscular disorders. "