|3.||Bone Diseases (Bone Disease)
|1.||Goswami, Ravinder: 14 articles (10/2015 - 01/2004)|
|2.||Bilezikian, John P: 12 articles (01/2015 - 09/2006)|
|3.||Gupta, Nandita: 11 articles (09/2013 - 01/2004)|
|4.||Thakker, Rajesh V: 11 articles (06/2013 - 05/2004)|
|5.||Rejnmark, Lars: 10 articles (08/2015 - 07/2008)|
|6.||Fukumoto, Seiji: 9 articles (11/2015 - 06/2002)|
|7.||Mosekilde, Leif: 9 articles (07/2015 - 07/2008)|
|8.||Rubin, Mishaela R: 9 articles (01/2015 - 12/2008)|
|9.||Brown, Edward M: 9 articles (06/2012 - 01/2004)|
|10.||Winer, Karen K: 8 articles (09/2014 - 12/2002)|
09/01/2008 - "We conclude that a twice-daily PTH 1-34 regimen provides a more effective treatment of hypoparathyroidism compared with once-daily treatment because it reduces the variation in serum calcium levels and accomplishes this at a lower total daily PTH 1-34 dose. "
12/01/2006 - "These results indicate that PTH therapy could be effective in correcting serum and urine calcium and the phosphate levels in hypoparathyroidism caused by activating mutation of CaR."
10/01/1998 - "We conclude that a twice-daily PTH regimen provides effective treatment of hypoparathyroidism and reduces the variation in serum calcium levels at a lower total daily PTH dose."
06/01/2010 - "We conclude that PTH 1-34 therapy is safe and effective in maintaining stable calcium homeostasis in children with hypoparathyroidism. "
06/01/1990 - "It might be suggested that 1 alpha-OHD3 is effective and safe in treating hypoparathyroidism because calcium absorption in intestine is promoted by 1 alpha-OHD3."
|2.||Vitamin DFDA LinkGeneric
08/01/1982 - "Comparative efficacy of various vitamin D metabolites in the treatment of various types of hypoparathyroidism."
09/01/2012 - "Vitamin D unresponsive hypoparathyroidism maybe safely and effectively controlled at long term by s. "
09/01/2012 - "Vitamin D nonresponsive hypoparathyroidism is uncommonly seen in the clinical practice. "
01/01/2010 - "Hypoparathyroidism is a chronic condition which requires a lifelong substitution with vitamin D analogues and careful monitoring. "
07/01/2008 - "However, in some subjects the PTH response to low vitamin D levels is blunted, which has been termed functional hypoparathyroidism (FHPT). "
|3.||Calcitriol (Calcijex)FDA LinkGeneric
01/18/1980 - "Calcitriol was used successfully to treat a patient with hypoparathyroidism during pregnancy. "
04/01/1981 - "It is suggested that calcitriol is an effective treatment of hypoparathyroidism during pregnancy and produces no ill effects on the baby."
11/01/2005 - "Patient 1 had postsurgical hypoparathyroidism and Munchausen's syndrome and consumed a pharmacologic dose of calcitriol. "
01/01/2001 - "She had been diagnosed as having idiopathic hypoparathyroidism and had been treated with calcitriol. "
11/01/1993 - "Reduced calcitriol requirements for treating hypoparathyroidism during lactation. "
|4.||Parathyroid Hormone (Parathormone)IBA
09/01/2015 - "This is the largest study that demonstrates the effectiveness of PTH(1-34) in the treatment of adult patients with postsurgical hypoparathyroidism, and it shows that PTH(1-34) may improve the mental and physical health in hypoparathyroid subjects."
09/01/2015 - "The objective of the study was to investigate the effects of 6 months of PTH(1-34) treatment in adult subjects with postoperative hypoparathyroidism and to evaluate quality-of-life changes. "
07/01/2014 - "There are no studies regarding the usefulness of intact parathyroid hormone (PTH) as a monitor of postoperative hypoparathyroidism tool in pediatrics. "
05/01/2014 - "Pharmacokinetics and pharmacodynamics of subcutaneous recombinant parathyroid hormone (1-84) in patients with hypoparathyroidism: an open-label, single-dose, phase I study."
12/01/2013 - "Efficacy and safety of recombinant human parathyroid hormone (1-84) in hypoparathyroidism (REPLACE): a double-blind, placebo-controlled, randomised, phase 3 study."
08/01/2012 - "This brings forth the importance of adequate phosphorus control in the management of hypoparathyroidism."
04/01/2005 - "Serum phosphorus level > 4.5 mg/dl on postoperative day 7 resulted the only independent factor predicting permanent hypoparathyroidism. "
09/01/2004 - "However, in the setting of chronic hypoparathyroidism, the degree of elevation of FGF-23 is insufficient to normalize serum phosphorus."
07/01/1964 - "[PROPOSAL OF A TEST FOR THE EVALUATION OF THE URINARY EXCRETION OF PHOSPHORUS IN HYPER- AND HYPOPARATHYROIDISM]."
11/02/1958 - "[Renal excretion of phosphorus in hypoparathyroidism]."
01/01/1986 - "In the second study PTH infusion was followed by a remarkable increase in 1,25(OH)2D serum levels as a result of 1 alpha-hydroxylase stimulation, which was much higher in patients with hypoparathyroidism. "
01/01/2013 - "Incident CD was associated with 25(OH)D and 1,25(OH)2D deficiency and a relative hypoparathyroidism that resolved following diagnosis. "
07/01/2003 - "Hypoparathyroidism in these patients has been managed by 1,25- (OH)(2)D(3) or 1alpha-OHD(3). "
06/01/1990 - "Hypoparathyroidism: practice and theoretical backgrounds for 1 alpha(OH)D3 treatment."
11/01/1988 - "In response to PTE, patients with hypoparathyroidism increased serum 1,25(OH)2D from 17 +/- 5 to 30 +/- 5 (SD) pg/ml (P less than 0.01). "
|7.||Teriparatide (Parathar)FDA Link
09/01/2015 - "In this pilot study, teriparatide therapy in patients with postthyroidectomy hypoparathyroidism was safe, rapidly eliminated hypocalcemic symptoms, and likely reduced the duration of hospitalization. "
09/01/2015 - "Teriparatide Therapy and Reduced Postoperative Hospitalization for Postsurgical Hypoparathyroidism."
08/01/2015 - "Treatment of unresponsive hypoparathyroidism when the oral route administration is not possible: considering subcutaneous teriparatide."
01/01/2014 - "Teriparatide (rhPTH) treatment in children with syndromic hypoparathyroidism."
12/01/2013 - "This review focuses on the use of PTH in the treatment of hypoparathyroidism, in the form of teriparatide [PTH(1-34)] and the full-length molecule, PTH(1-84). "
|8.||Cholecalciferol (Vitamin D3)FDA Link
02/01/2014 - "To assess the efficacy and safety of a single administration of vitamin D3 for postoperative hypoparathyroidism. "
03/01/2003 - "Effective counterbalance was provided by hypoparathyroidism, hypercalcitoninism, and the key regulator 24-hydroxylase, preventing the development of vitamin D(3) toxicosis."
04/01/1998 - "Before vitamin D3 treatment, the sigmoidal curve deviated to the left in both types of hypoparathyroidism. "
12/01/1997 - "Old age, male gender, duration of haemodialysis, hyperphosphataemia associated with hypoparathyroidism and raised Vitamin D3 are predisposing factors."
07/01/1995 - "Basal/maximum ratio of serum PTH, which reflects the basal secretory state of parathyroid glands, was increased in 9 hypoparathyroid patients treated with vitamin D3 (VD3) [7 patients with idiopathic hypoparathyroidism] and in seven of nine parathyroid adenectomized patients. "
|9.||sevelamer (RenaGel)FDA Link
09/01/2010 - "Sevelamer is an effective means of treatment for chronic hyperphosphatemic HD patients, especially those with hypoparathyroidism."
12/01/2007 - "However, it remains unknown whether sevelamer restores bone metabolism in hemodialysis patients with low bone turnover osteodystrophy and hypoparathyroidism. "
06/01/2007 - "However, among patients with relative hypoparathyroidism, sevelamer therapy may be beneficial for the prevention of adynamic bone disease."
01/01/2007 - "This study was conducted to clarify the therapeutic effect of a non-calcemic phosphate binder, sevelamer hydrochloride (sevelamer), for hypoparathyroidism in hemodialysis patients with or without diabetes mellitus. "
09/01/2010 - "In patients with hypoparathyroidism, calcium acetate treatment decreased serum iPTH at the end of the study, while sevelamer did not. "
01/01/2013 - "rhPTH (1-34) is an effective treatment for patients with hypoparathyroidism due to gain-of-function mutations in the calcium-sensing receptor. "
01/01/2015 - "We report the case of a female infant with hypoparathyroidism due to an activating mutation in the calcium-sensing receptor gene. "
05/01/2014 - "Primary hypoparathyroidism can occur due to an activating mutation of calcium sensing receptor (CaSR). "
03/01/2014 - "Analysis of AP2S1, a calcium-sensing receptor regulator, in familial and sporadic isolated hypoparathyroidism."
01/01/2013 - "A congenital cause of her hypoparathyroidism was considered, and genetic testing confirmed heterozygosity for a gain-of-function mutation in the calcium-sensing receptor gene associated with autosomal dominant familial isolated hypoparathyroidism (ADH). "
03/01/1983 - "Total thyroidectomy is best avoided in most cases, considering the price of hypoparathyroidism and the lack of significant improvement in survival compared with lesser ablative techniques. "
01/01/2014 - "Partial thyroidectomy was more cost-effective when the risks of RLN injury and definitive hypoparathyroidism were greater than 8% and 9% in total thyroidectomy, respectively. "
12/01/1984 - "The risk of permanent hypoparathyroidism is higher in patients after total thyroidectomy without apparent improvement in survival rates when compared with less extensive resections. "
10/01/2015 - "ObjectiveThe aim of the present study was to identify a fast, efficient and low-cost method to diagnose hypoparathyroidism after total thyroidectomy.Materials"
07/01/2015 - "The aim of this study was to investigate the rate of recovery from postoperative, permanent hypoparathyroidism in patients undergoing thyroidectomy without parathyroid autotransplantation. "
|2.||Transplantation (Transplant Recipients)
09/01/2000 - "To evaluate the therapeutic efficacy of transplantation of cultured human fetal parathyroid gland (chf-PTG) cells in treating patients with primary or secondary hypoparathyroidism. "
10/01/2014 - "Auto-transplantation protects against permanent hypoparathyroidism, whereas low PTH day 1 is associated with high risk."
06/01/2011 - "Although athymia is corrected by allogeneic thymus transplantation, treatment options for hypoparathyroidism have been unsatisfactory. "
01/01/2011 - "Intraoperative PTH assay may allow intraoperative monitoring of parathyroid function, predicting postoperative outcomes, may identify patients at risk of developing postoperative hypoparathyroidism, guiding surgeons to re-examine removed specimens for inadvertently removed parathyroid tissue with possible auto transplantation, or more practically a guide to early replacement therapy to prevent hypocalcaemia, leading to safe and early hospital discharge. "
01/01/2011 - "to test the sensitivity and specificity of intraoperative rapid PTH assay test in predicting permanent postoperative hypoparathyroidism, and applicability to guide the search for inadvertently removed parathyroid glands for possible auto transplantation. "
01/01/2015 - "Iatrogenic removal of the parathyroid glands increased the risk of permanent hypoparathyroidism compared with those without iatrogenic parathyroidectomy. "
01/01/2014 - "Transient hypoparathyroidism was increased when incidental parathyroidectomy occurred (odds ratio 1.83, 95% confidence interval 1.04 to 3.23, P = 0.036) on multivariate regression analysis, but was not influenced by the actual number of parathyroid glands removed. "
01/01/2014 - "After discharge, two patients (in total parathyroidectomy group) were readmitted because of postoperative hypoparathyroidism. "
11/01/2013 - "While this case is unique for the length of follow-up, the continuous and detailed description of NSHPT after total parathyroidectomy in its adult phenotype, and the treatment of hypoparathyroidism with rhPTH (1-84). "
02/01/2011 - "There was no significant association between incidental parathyroidectomy and the sex of the patient, the age of the patient, the type of thyroid surgery, or transient or permanent hypoparathyroidism. "
11/01/1991 - "Our results demonstrate that replantation of autologous cryopreserved parathyroid tissue is safe and effective therapy for permanent postoperative hypoparathyroidism. "
01/01/2015 - "Replantation with cryopreserved parathyroid for permanent hypoparathyroidism: a case report and review of literatures."
11/01/1997 - "Hypoparathyroidism post-PTX developed in 4/37 patients, but could be overcome by replantation of cryoconserved parathyroid tissue. "
11/01/1988 - "The principal post-operative complication is hypoparathyroidism which can be prevented by cryopreservation of a fragment of the lesion for possible subsequent reimplantation. "
10/08/1988 - "Systematic parathyroid gland dissection and reimplantation account for the absence of late hypoparathyroidism."
09/01/2015 - "We describe a case of RT in which hypoparathyroidism resolved after treatment targeted the mechanical compression and the fibroinflammatory milieu of the patient's thyroidal disease. "
08/01/1983 - "A 22-year-old woman developed hypoparathyroidism in 1970, 10 months after treatment of hyperthyroidism with I-131. "
10/25/2003 - "Hypothyroidism and hypoparathyroidism are common complications after treatment (surgery, radiotherapy and/or chemotherapy) for laryngo-pharyngeal carcinoma and other malignancies in the neck region."
09/01/2013 - "Here, we report a 50-year-old female with DCM, induced by idiopathic hypoparathyroidism, that improved after treatment with calcium. "
04/01/2008 - "Although the incidence of hypoparathyroidism after treatment for head and neck cancer is low, testing of serum calcium is easily performed during thyroid function evaluation. "