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Hypochlorous Acid (Hypochlorite)

An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
Also Known As:
Hypochlorite; Hypochlorous Acids; Hypochlorous acid
Networked: 677 relevant articles (34 outcomes, 50 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Hawkins, Clare L: 11 articles (01/2021 - 09/2008)
2. Malle, Ernst: 8 articles (12/2021 - 01/2002)
3. Davies, Michael J: 8 articles (01/2021 - 09/2008)
4. Kettle, Anthony J: 8 articles (01/2020 - 03/2003)
5. Rayner, Benjamin S: 7 articles (10/2020 - 10/2017)
6. Batteux, Frédéric: 6 articles (01/2022 - 05/2009)
7. Whiteman, Matthew: 6 articles (10/2010 - 11/2003)
8. Nakajima, Masatoshi: 5 articles (04/2022 - 03/2014)
9. Bartosz, Grzegorz: 5 articles (02/2022 - 01/2010)
10. Winterbourn, Christine C: 5 articles (07/2014 - 03/2003)

Related Diseases

1. Wounds and Injuries (Trauma)
2. Sinusitis
3. Neoplasms (Cancer)
4. Infections
5. Breast Neoplasms (Breast Cancer)
01/01/2023 - "The probe was used in an application to visualize ClO- in human breast cancer cells which can be helpful for investigating the functions of hypochlorite in living cells. "
01/01/2023 - "A small-molecule fluorogenic probe for the detection of hypochlorite and its application in the bio-imaging of human breast cancer cells."
03/30/2012 - "Our study demonstrated that HDL under hypochlorite-induced oxidative stress stimulates breast cancer cell migration, invasion, adhesion to HUVEC and ECM, thereby promoting metastasis of breast cancer. "
03/30/2012 - "The purpose of this study is to determine the different effects of normal and oxidized (caused by hypochlorite-induced oxidative stress) HDL on breast cancer cell metastasis. "
03/30/2012 - "We found hypochlorite-oxidized HDL dramatically promotes breast cancer cell pulmonary metastasis (133.4% increase at P < 0.0 l for MDA-MB-231 by mammary fat pad injection; 164.3% increase at P < 0.01 for MCF7 by tail vein injection) and hepatic metastasis (420% increase at P < 0.0 l for MDA-MB-231 by mammary fat pad injection; 1840% fold increase at P < 0.001 for MCF7 by tail vein injection) in nude mice, and stimulates higher cell invasion (85.1% increase at P < 0.00 l for MDA-MB-231; 88.8% increase at P < 0.00 l for MCF7;), TC-HUVEC adhesion (43.4% increase at P < 0.00 l for MDA-MB-231; 35.2% increase at P < 0.00 l for MCF7), and TC-ECM attachment (41.0% increase at P < 0.00 l for MDA-MB-231; 26.7% increase at P < 0.05 for MCF7) in vitro compared with normal HDL. "

Related Drugs and Biologics

1. Local Anti-Infective Agents (Antiseptics)
2. octenidine
3. polihexanide
4. Antioxidants
5. Amino Acids
6. 2,2'-azobis(2-amidinopropane) (ABAP)
7. Solutions
8. Oxidants (Oxidizing Agents)
9. Peroxidase (Myeloperoxidase)
10. Sodium Hypochlorite (Clorox)

Related Therapies and Procedures

1. Debridement
2. Plastic Surgery Procedures
3. Topical Administration
4. Radiotherapy
5. Therapeutics