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Hypochlorous Acid (Hypochlorite)

An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
Also Known As:
Hypochlorite; Hypochlorous Acids; Hypochlorous acid
Networked: 306 relevant articles (7 outcomes, 18 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Whiteman, Matthew: 7 articles (10/2010 - 11/2003)
2. Kettle, Anthony J: 6 articles (09/2015 - 03/2003)
3. Malle, Ernst: 6 articles (06/2010 - 01/2002)
4. Winterbourn, Christine C: 5 articles (07/2014 - 03/2003)
5. Cheung, Nam Sang: 5 articles (10/2010 - 01/2005)
6. Davies, Michael J: 4 articles (06/2013 - 09/2008)
7. Cheung, Gary S P: 4 articles (08/2010 - 10/2007)
8. Armstrong, Jeffrey S: 4 articles (03/2008 - 01/2005)
9. Hammerschmidt, Stefan: 4 articles (06/2007 - 02/2002)
10. Siau, Jia Ling: 4 articles (04/2007 - 11/2003)

Related Diseases

1. Photosensitivity Disorders (Photodermatitis)
2. Breast Neoplasms (Breast Cancer)
01/01/2012 - "Our study demonstrated that HDL under hypochlorite-induced oxidative stress stimulates breast cancer cell migration, invasion, adhesion to HUVEC and ECM, thereby promoting metastasis of breast cancer. "
01/01/2012 - "The purpose of this study is to determine the different effects of normal and oxidized (caused by hypochlorite-induced oxidative stress) HDL on breast cancer cell metastasis. "
01/01/2012 - "We found hypochlorite-oxidized HDL dramatically promotes breast cancer cell pulmonary metastasis (133.4% increase at P < 0.0 l for MDA-MB-231 by mammary fat pad injection; 164.3% increase at P < 0.01 for MCF7 by tail vein injection) and hepatic metastasis (420% increase at P < 0.0 l for MDA-MB-231 by mammary fat pad injection; 1840% fold increase at P < 0.001 for MCF7 by tail vein injection) in nude mice, and stimulates higher cell invasion (85.1% increase at P < 0.00 l for MDA-MB-231; 88.8% increase at P < 0.00 l for MCF7;), TC-HUVEC adhesion (43.4% increase at P < 0.00 l for MDA-MB-231; 35.2% increase at P < 0.00 l for MCF7), and TC-ECM attachment (41.0% increase at P < 0.00 l for MDA-MB-231; 26.7% increase at P < 0.05 for MCF7) in vitro compared with normal HDL. "
01/01/2012 - "Human breast cancer cell lines were treated with normal and hypochlorite-oxidized HDL, and then cell metastasis potency in vivo and the abilities of migration, invasion, adhesion to HUVEC and ECM in vitro were examined. "
01/01/2012 - "Hypochlorite-induced oxidative stress elevates the capability of HDL in promoting breast cancer metastasis."
3. Shock
4. Hepatitis
5. Skin Diseases

Related Drugs and Biologics

1. Peroxidase (Myeloperoxidase)
2. Superoxides (Superoxide)
3. Catalase
4. Superoxide Dismutase
5. Sodium Hypochlorite (Clorox)
6. Hydrogen Peroxide (Hydroperoxide)
7. Oxidants (Oxidizing Agents)
8. Disinfectants
9. Antigens
10. Lipoproteins (Lipoprotein)

Related Therapies and Procedures

1. Transplantation (Transplant Recipients)
2. Intravenous Injections
3. Lenses
4. Injections
5. Intravenous Infusions